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Cerebrovascular diseases (CVD) can lead to stroke and dementia. Stroke is the second leading cause of death world wide and dementia incidence is increasing by the year. There are several markers of CVD that are visible on brain imaging,…

Lung cancer is the leading cause of cancer related mortality by a significant margin. While new technologies, such as image segmentation, have been paramount to improved detection and earlier diagnoses, there are still significant…

Computer Vision and Pattern Recognition · Computer Science 2022-09-20 Marguerite B. Basta , Sarfaraz Hussein , Hsiang Hsu , Flavio P. Calmon

Brain lesion volume measured on T2 weighted MRI images is a clinically important disease marker in multiple sclerosis (MS). Manual delineation of MS lesions is a time-consuming and highly operator-dependent task, which is influenced by…

Image and Video Processing · Electrical Eng. & Systems 2023-11-28 Hang Zhang , Jinwei Zhang , Qihao Zhang , Jeremy Kim , Shun Zhang , Susan A. Gauthier , Pascal Spincemaille , Thanh D. Nguyen , Mert R. Sabuncu , Yi Wang

Stroke is a leading cause of long-term disability and the second most common cause of death worldwide. Although acute treatments have advanced, recovery remains challenging and limited. Brain-computer interfaces (BCIs) have emerged as a…

Neurons and Cognition · Quantitative Biology 2025-10-10 Aniana Cruz , Marko Kuzmanoski , Gabriel Pires

Accurate and interpretable mortality risk prediction in intensive care units (ICUs) remains a critical challenge due to the irregular temporal structure of electronic health records (EHRs), the complexity of longitudinal disease…

Machine Learning · Computer Science 2026-03-10 Zahra Jafari , Azadeh Zamanifar , Amirfarhad Farhadi

Stroke affected millions annually, yet poor symptom recognition often delayed care-seeking. To address risk recognition gap, we developed a passive surveillance system for early stroke risk detection using patient-reported symptoms among…

Alzheimer's disease (AD) affects 50 million people worldwide and is projected to overwhelm 152 million by 2050. AD is characterized by cognitive decline due partly to disruptions in metabolic brain connectivity. Thus, early and accurate…

The segmentation and classification of carotid plaques in ultrasound images play important roles in the treatment of atherosclerosis and assessment for the risk of stroke. Although deep learning methods have been used for carotid plaque…

Image and Video Processing · Electrical Eng. & Systems 2023-11-21 Haitao Gan , Ran Zhou , Yanghan Ou , Furong Wang , Xinyao Cheng , Aaron Fenster

Ischemic stroke is a severe condition caused by the blockage of brain blood vessels, and can lead to the death of brain tissue due to oxygen deprivation. Thrombectomy has become a common treatment choice for ischemic stroke due to its…

Image and Video Processing · Electrical Eng. & Systems 2024-08-05 Caiwen Jiang , Tianyu Wang , Xiaodan Xing , Mianxin Liu , Guang Yang , Zhongxiang Ding , Dinggang Shen

Heart disease remains the leading cause of death in the United States. Compared with risk assessment guidelines that require manual calculation of scores, machine learning-based prediction for disease outcomes such as mortality can be…

Machine Learning · Computer Science 2018-12-13 Laura A. Barrett , Seyedeh Neelufar Payrovnaziri , Jiang Bian , Zhe He

Major Adverse Cardiovascular Events (MACE) remain the leading cause of mortality globally, as reported in the Global Disease Burden Study 2021. Opportunistic screening leverages data collected from routine health check-ups and multimodal…

Computer Vision and Pattern Recognition · Computer Science 2025-06-25 Jialu Pi , Juan Maria Farina , Rimita Lahiri , Jiwoong Jeong , Archana Gurudu , Hyung-Bok Park , Chieh-Ju Chao , Chadi Ayoub , Reza Arsanjani , Imon Banerjee

Stroke is the second leading cause of mortality worldwide. Immediate attention and diagnosis play a crucial role regarding patient prognosis. The key to diagnosis consists in localizing and delineating brain lesions. Standard stroke…

Image and Video Processing · Electrical Eng. & Systems 2024-09-05 Santiago Gómez , Daniel Mantilla , Gustavo Garzón , Edgar Rangel , Andrés Ortiz , Franklin Sierra-Jerez , Fabio Martínez

In an emergency room (ER) setting, stroke triage or screening is a common challenge. A quick CT is usually done instead of MRI due to MRI's slow throughput and high cost. Clinical tests are commonly referred to during the process, but the…

Computer Vision and Pattern Recognition · Computer Science 2022-06-29 Tongan Cai , Haomiao Ni , Mingli Yu , Xiaolei Huang , Kelvin Wong , John Volpi , James Z. Wang , Stephen T. C. Wong

A stroke occurs when an artery in the brain ruptures and bleeds or when the blood supply to the brain is cut off. Blood and oxygen cannot reach the brain's tissues due to the rupture or obstruction resulting in tissue death. The Middle…

Image and Video Processing · Electrical Eng. & Systems 2022-05-10 Ujjwal Upadhyay , Mukul Ranjan , Satish Golla , Swetha Tanamala , Preetham Sreenivas , Sasank Chilamkurthy , Jeyaraj Pandian , Jason Tarpley

Depression has been the leading cause of mental-health illness worldwide. Major depressive disorder (MDD), is a common mental health disorder that affects both psychologically as well as physically which could lead to loss of lives. Due to…

Computer Vision and Pattern Recognition · Computer Science 2019-09-05 Anupama Ray , Siddharth Kumar , Rutvik Reddy , Prerana Mukherjee , Ritu Garg

Deep learning has demonstrated success in many applications; however, their use in healthcare has been limited due to the lack of transparency into how they generate predictions. Algorithms such as Recurrent Neural Networks (RNNs) when…

Machine Learning · Computer Science 2021-01-14 Long V. Ho , Melissa D. Aczon , David Ledbetter , Randall Wetzel

Coronary Artery Disease (CAD) remains a leading cause of morbidity and mortality worldwide. Early detection is critical to recover patient outcomes and decrease healthcare costs. In recent years, machine learning (ML) advancements have…

Artificial Intelligence · Computer Science 2026-03-10 Karan Kumar Singh , Nikita Gajbhiye , Gouri Sankar Mishra

Computer-aided early diagnosis of Alzheimer's disease (AD) and its prodromal form mild cognitive impairment (MCI) based on structure Magnetic Resonance Imaging (sMRI) has provided a cost-effective and objective way for early prevention and…

Image and Video Processing · Electrical Eng. & Systems 2021-11-16 Xin Zhang , Liangxiu Han , Wenyong Zhu , Liang Sun , Daoqiang Zhang

With a mortality rate of 5.4 million lives worldwide every year and a healthcare cost of more than 16 billion dollars in the USA alone, sepsis is one of the leading causes of hospital mortality and an increasing concern in the ageing…

Machine Learning · Computer Science 2021-05-12 Margherita Rosnati , Vincent Fortuin

When the blood supply to the brain is obstructed by a clot, oxygen delivery to brain tissues becomes insufficient, leading to cellular necrosis. In healthcare settings, accurately identifying and delineating ischemic lesion boundaries is…

Image and Video Processing · Electrical Eng. & Systems 2026-05-22 Sayed Amir Mousavi Mobarakeh
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