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Stimulated Brillouin scattering drives a coherent interaction between optical signals and acoustic phonons and this effect can be used for storing optical information in acoustic waves. An important consideration arises when multiple…

Bright-field microscopy, a cost-effective solution for live-cell culture, is often the only resource available, along with standard CPUs, for many low-budget labs. The inherent challenges of bright-field images -- their noisiness, low…

Quantitative Methods · Quantitative Biology 2025-11-03 Surajit Das , Pavel Zun

Microscopes are vital pieces of equipment in much of biological research and medical diagnostics. However, access to a microscope can represent a bottleneck in research, especially in lower-income countries. `Smart' computer controlled…

Instrumentation and Detectors · Physics 2022-07-08 Samuel McDermott , Filip Ayazi , Joel Collins , Joe Knapper , Julian Stirling , Richard Bowman , Pietro Cicuta

This paper presents a soft-label anonymous gastric X-ray image distillation method based on a gradient descent approach. The sharing of medical data is demanded to construct high-accuracy computer-aided diagnosis (CAD) systems. However, the…

Image and Video Processing · Electrical Eng. & Systems 2024-03-22 Guang Li , Ren Togo , Takahiro Ogawa , Miki Haseyama

Medical data employed in research frequently comprises sensitive patient health information (PHI), which is subject to rigorous legal frameworks such as the General Data Protection Regulation (GDPR) or the Health Insurance Portability and…

Image and Video Processing · Electrical Eng. & Systems 2024-10-17 Moritz Rempe , Lukas Heine , Constantin Seibold , Fabian Hörst , Jens Kleesiek

Imaging data is one of the most important fundamentals in the current life sciences. We aimed to construct an ontology to describe imaging metadata as a data schema of the integrated database for optical and electron microscopy images…

Digital Libraries · Computer Science 2021-11-23 Satoshi Kume , Hiroshi Masuya , Yosky Kataoka , Norio Kobayashi

Image simulation remains under-exploited for the most widely used biological phase microscopy methods, because of difficulties in simulating partially coherent illumination. We describe an open-source toolbox, microlith…

Optics · Physics 2014-05-14 Shalin B. Mehta , Rudolf Oldenbourg

This study investigates the mechanical properties of colon cancer cells through Brillouin microscopy, focusing on the differentiation between wild-type (WT) and CRISPR-modified cells. Brillouin microspectroscopy, a non-invasive technique,…

Biological Physics · Physics 2025-07-09 Mykyta Kizilov , Vsevolod Cheburkanov , Vladislav V. Yakovlev

Distributed optical fiber Brillouin sensors detect the temperature and strain along a fiber according to the local Brillouin frequency shift, which is usually calculated by the measured Brillouin spectrum using Lorentzian curve fitting. In…

Signal Processing · Electrical Eng. & Systems 2020-01-13 Yiqing Chang , Hao Wu , Can Zhao , Li Shen , Songnian Fu , Ming Tang

Most of us are not experts in specific fields, such as ornithology. Nonetheless, we do have general image and language understanding capabilities that we use to match what we see to expert resources. This allows us to expand our knowledge…

Computer Vision and Pattern Recognition · Computer Science 2021-11-08 Subhabrata Choudhury , Iro Laina , Christian Rupprecht , Andrea Vedaldi

Microscopes are essential for biomechanics and hydrodynamical investigation of small aquatic organisms. We report a DIY microscope (GLUBscope) that enables the visualization of organisms from two orthogonal imaging planes (top and side…

Quantitative Methods · Quantitative Biology 2023-07-26 Brian T. Le , Katherine M. Auer , David A. Lopez , Justin P. Shum , Brian Suarsana , Ga-Young Kelly Suh , Per Niklas Hedde , Siavash Ahrar

Stimulated Brillouin interactions mediate nonlinear coupling between photons and acoustic phonons through an optomechanical three-wave interaction. Though these nonlinearities were previously very weak in silicon photonic systems, the…

Optics · Physics 2017-08-02 Eric A. Kittlaus , Nils T. Otterstrom , Peter T. Rakich

Ultra-narrow optical spectral features resulting from highly dispersive light-matter interactions are essential for a broad range of applications such as spectroscopy, slow-light, and high-precision sensing. Features approaching sub-MHz, or…

Optics · Physics 2022-06-10 Neel Choksi , Yi Liu , Rojina Ghasemi , Li Qian

The future of bioimage analysis is increasingly defined by the development and use of tools that rely on deep learning and artificial intelligence (AI). For this trend to continue in a way most useful for stimulating scientific progress, it…

Other Quantitative Biology · Quantitative Biology 2023-08-31 Damian Edward Dalle Nogare , Matthew Hartley , Joran Deschamps , Jan Ellenberg , Florian Jug

Image-based virtual try-on aims to synthesize a naturally dressed person image with a clothing image, which revolutionizes online shopping and inspires related topics within image generation, showing both research significance and…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Dan Song , Xuanpu Zhang , Juan Zhou , Weizhi Nie , Ruofeng Tong , Mohan Kankanhalli , An-An Liu

Imaging dynamical processes at interfaces and on the nanoscale is of great importance throughout science and technology. While light-optical imaging techniques often cannot provide the necessary spatial resolution, electron-optical…

Motivation: Novel machine learning and statistical modeling studies rely on standardized comparisons to existing methods using well-studied benchmark datasets. Few tools exist that provide rapid access to many of these datasets through a…

Load-bearing tissues are typically fortified by networks of protein fibers, often with preferential orientations. This fiber structure imparts the tissues with direction-dependent mechanical properties optimized to support specific external…

Biological Physics · Physics 2022-03-03 Amira M. Eltony , Peng Shao , Seok-Hyun Yun

Raman spectroscopy is a non-destructive and label-free chemical analysis technique, which plays a key role in the analysis and discovery cycle of various branches of science. Nonetheless, progress in Raman spectroscopic analysis is still…