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Transformers have become methods of choice in many applications thanks to their ability to represent complex interactions between elements. However, extending the Transformer architecture to non-sequential data such as molecules and…

Machine Learning · Computer Science 2022-04-27 Yoni Choukroun , Lior Wolf

Quantum computing has demonstrated potential for solving complex optimization problems; however, its application to spatial regionalization remains underexplored. Spatial contiguity, a fundamental constraint requiring spatial entities to…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-06-03 Yunhan Chang , Amr Magdy , Federico M. Spedalieri

Quantum computers can be used to address molecular structure, materials science and condensed matter physics problems, which currently stretch the limits of existing high-performance computing resources. Finding exact numerical solutions to…

Quantum machines are among the most promising technologies expected to provide significant improvements in the following years. However, bridging the gap between real-world applications and their implementation on quantum hardware is still…

The electronic structure problem is one of the main problems in modern theoretical chemistry. While there are many already-established methods both for the problem itself and its applications like semi-classical or quantum dynamics, it…

Quantum Physics · Physics 2024-10-25 Martin Beseda , Silvie Illésová , Saad Yalouz , Bruno Senjean

We explore the industrial and scientific applicability of the VQE-LSTM framework by integrating meta-learning with GPU accelerated quantum simulation using NVIDIA's CUDA-Q (CUDAQ) platform. This work demonstrates how an LSTM-FC…

Quantum Physics · Physics 2026-02-18 Yun-Hsuan Chen , Jen-Yu Chang , Tsung-Wei Huang , En-Jui Kuo

Geometric quantum computation offers a practical strategy toward robust quantum computation due to its inherently error tolerance. However, the rigorous geometric conditions lead to complex and/or error-disturbed quantum controls,…

Quantum Physics · Physics 2022-07-28 Tao Chen , Zheng-Yuan Xue , Z. D. Wang

While quantum computers are a very promising tool for the far future, in their current state of the art they remain limited both in size and quality. This has given rise to hybrid quantum-classical algorithms, where the quantum device…

Quantum Physics · Physics 2026-01-26 Yury Chernyak , Ijaz Ahamed Mohammad , Martin Plesch

The ADAPT-VQE algorithm is a promising method for generating a compact ansatz based on derivatives of the underlying cost function, and it yields accurate predictions of electronic energies for molecules. In this work we report the…

Quantum computing is moving beyond its early stage and seeking for commercial applications in chemical and biomedical sciences. In the current noisy intermediate-scale quantum computing era, quantum resource is too scarce to support these…

Quantum Physics · Physics 2023-03-08 Honghui Shang , Yi Fan , Li Shen , Chu Guo , Jie Liu , Xiaohui Duan , Fang Li , Zhenyu Li

The integration of quantum machine learning with classical deep learning offers promising avenues for medical image analysis by mapping data into high-dimensional Hilbert spaces. However, effectively unifying these distinct paradigms…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Yasmin Rodrigues Sobrinho , João Renato Ribeiro Manesco , João Paulo Papa

Over the last decade, researchers have been working to improve a crucial aspect of quantum computing to predict Hamiltonian energy of solids. Quantum algorithms such as Variational Quantum Eigensolver (VQE) and Variational Quantum Deflation…

Materials Science · Physics 2025-09-03 Naman Khandelwal , Nidhi Verma , Pooja Jamdagni , Ashok Kumar

Molecular docking (MD) is a crucial task in drug design, which predicts the position, orientation, and conformation of the ligand when bound to a target protein. It can be interpreted as a combinatorial optimization problem, where quantum…

Chemical Physics · Physics 2024-04-15 Yunting Li , Xiaopeng Cui , Zhaoping Xiong , Bowen Liu , Bi-Ying Wang , Runqiu Shu , Nan Qiao , Man-Hong Yung

The geometric formulation of quantum mechanics is a very interesting field of research which has many applications in the emerging field of quantum computation and quantum information, such as schemes for optimal quantum computers. In this…

Quantum Physics · Physics 2014-04-24 Ole Andersson , Hoshang Heydari

Efficiently embedding high-dimensional datasets onto noisy and low-qubit quantum systems is a significant barrier to practical Quantum Machine Learning (QML). Approaches such as quantum autoencoders can be constrained by current hardware…

Quantum Physics · Physics 2025-06-25 Hevish Cowlessur , Tansu Alpcan , Chandra Thapa , Seyit Camtepe , Neel Kanth Kundu

Quantum chemistry calculations of large, strongly correlated systems are typically limited by the computation cost that scales exponentially with the size of the system. Quantum algorithms, designed specifically for quantum computers, can…

The QED-C suite of Application-Oriented Benchmarks provides the ability to gauge performance characteristics of quantum computers as applied to real-world applications. Its benchmark programs sweep over a range of problem sizes and inputs,…

The variational quantum eigensolver (VQE) is a promising method for simulating molecular systems on near-term quantum computers. This approach employs energy estimation; however, other relevant molecular properties can be extracted from the…

Accurate molecular geometries are a prerequisite for reliable quantum-chemical predictions, yet density functional theory (DFT) optimization remains a major bottleneck for high-throughput molecular screening. Here we present GeoOpt-Net, a…

Chemical Physics · Physics 2026-02-02 Chengchun Liu , Wendi Cai , Boxuan Zhao , Fanyang Mo

The Variational Quantum Eigensolver (VQE) is a hybrid quantum-classical algorithm for computing ground state energies of molecular systems. We implement VQE to calculate the potential energy surface of the hydrogen molecule (H$_2$) across…

Quantum Physics · Physics 2026-01-16 Rylan Malarchick , Ashton Steed
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