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We study parameter identification problems in a structured population model without mutations. Given measurements of the total population size or critical points of the population, we aim to recover its growth rate, death rate or initial…

Analysis of PDEs · Mathematics 2019-09-04 Alexander Lorz , Jan-Frederik Pietschmann , Matthias Schlottbom

In this paper, we present an approach for modeling bio-tissues that incorporates the variability in properties as part of their characteristics. This is achieved by considering the parameters of the model of a biomaterial to themselves be…

Tissues and Organs · Quantitative Biology 2013-12-11 Srikrishna Doraiswamy , Arun R. Srinivasa

The study of pattern emergence together with exploration of the exemplar Turing model is enjoying a renaissance both from theoretical and experimental perspective. Here, we implement a stability analysis of spatially dependent reaction…

Pattern Formation and Solitons · Physics 2019-11-06 Michal Kozák , Eamonn A Gaffney , Václav Klika

Tethered particle motion experiments are versatile single-molecule techniques enabling one to address in vitro the molecular properties of DNA and its interactions with various partners involved in genetic regulations. These techniques…

Biological Physics · Physics 2019-09-05 Manoel Manghi , Nicolas Destainville , Annaël Brunet

We study a p-adic reaction-diffusion system and the associated Turing patterns. We establish an instability criteria and show that the Turing patterns are not classical patterns consisting of alternating domains. Instead of this, a Turing…

Analysis of PDEs · Mathematics 2021-09-07 W. A. Zúñiga-Galindo

Inferring physical parameters of turbulent flows by assimilation of data measurements is an open challenge with key applications in meteorology, climate modeling and astrophysics. Up to now, spectral nudging was applied for empirical…

Fluid Dynamics · Physics 2018-10-29 P. Clark Di Leoni , A. Mazzino , L. Biferale

The explosion of data throughout the biomedical sciences provides unprecedented opportunities to learn about the dynamics of evolution and disease progression, but harnessing these large and diverse datasets remains challenging. Here, we…

Quantitative Methods · Quantitative Biology 2019-12-03 Sam F. Greenbury , Mauricio Barahona , Iain G. Johnston

This study investigates transient wave dynamics in Turing pattern formation, focusing on waves emerging from localised disturbances. While the traditional focus of diffusion-driven instability has primarily centred on stationary solutions,…

Pattern Formation and Solitons · Physics 2024-03-15 Václav Klika , Eamonn A. Gaffney , Philip K. Maini

Parameter inference and uncertainty quantification are important steps when relating mathematical models to real-world observations, and when estimating uncertainty in model predictions. However, methods for doing this can be…

Quantitative Methods · Quantitative Biology 2025-08-27 Michael J. Plank , Matthew J. Simpson

The advent of novel nonlinear materials has stirred unprecedented interest in exploring the use of temporal inhomogeneities to achieve novel forms of wave control, amidst the greater vision of engineering metamaterials across both space and…

Optics · Physics 2022-11-24 Emanuele Galiffi , Shixiong Yin , Andrea Alù

Temporal causal representation learning is a powerful tool for uncovering complex patterns in observational studies, which are often represented as low-dimensional time series. However, in many real-world applications, data are…

Machine Learning · Computer Science 2025-07-21 Jianhong Chen , Meng Zhao , Mostafa Reisi Gahrooei , Xubo Yue

The dynamics of systems biological processes are usually modeled by a system of ordinary differential equations (ODEs) with many unknown parameters that need to be inferred from noisy and sparse measurements. Here, we introduce…

Quantitative Methods · Quantitative Biology 2022-02-04 Mitchell Daneker , Zhen Zhang , George Em Karniadakis , Lu Lu

Nature is a blossoming of regular structures, signature of self-organization of the underlying microscopic interacting agents. Turing theory of pattern formation is one of the most studied mechanisms to address such phenomena and has been…

Pattern Formation and Solitons · Physics 2025-10-22 Riccardo Muolo , Lorenzo Giambagli , Hiroya Nakao , Duccio Fanelli , Timoteo Carletti

Defects are a ubiquitous feature of ordered media. They have certain universal features, independent of the underlying physical system, reflecting their topological origins. While the topological properties of defects are robust, they…

Soft Condensed Matter · Physics 2021-02-24 Chiqun Zhang , Amit Acharya , Alan C. Newell , Shankar C. Venkataramani

Turing patterns can be observed in reaction-diffusion systems where chemical species have different diffusion constants. In recent years, several studies investigated the effects of noise on Turing patterns and showed that the parameter…

Computational Physics · Physics 2013-10-30 Yang Cao , Radek Erban

The identification and classification of transitions in topological and microstructural regimes in pattern-forming processes are critical for understanding and fabricating microstructurally precise novel materials in many application…

Materials Science · Physics 2022-08-12 Marcin Abram , Keith Burghardt , Greg Ver Steeg , Aram Galstyan , Remi Dingreville

Ordinal Patterns are a time-series data analysis tool used as a preliminary step to construct the Permutation Entropy which itself allows the same characterization of dynamics as chaotic or regular as more theoretical constructs such as the…

Adaptation and Self-Organizing Systems · Physics 2021-02-24 I. Gunther , Arjendu K. Pattanayak , Andrés Aragoneses

In this work we consider the problem of extracting a set of interaction parameters from an high-dimensional dataset describing T independent configurations of a complex system composed of N binary units. This problem is formulated in the…

Statistical Mechanics · Physics 2013-11-04 Iacopo Mastromatteo

For cellular functions like division and polarization, protein pattern formation driven by NTPase cycles is a central spatial control strategy. Operating far from equilibrium, no general theory links microscopic reaction networks and…

Biological Physics · Physics 2024-10-01 Henrik Weyer , Tobias A. Roth , Erwin Frey

Living cells communicate information about physiological conditions by producing signaling molecules in a specific timed manner. Different conditions can result in the same total amount of a signaling molecule, differing only in the pattern…

Molecular Networks · Quantitative Biology 2018-10-09 Jackson O'Brien , Arvind Murugan