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Related papers: Finding low-complexity DNA sequences with longdust

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Long Context Understanding (LCU) is a critical area for exploration in current large language models (LLMs). However, due to the inherently lengthy nature of long-text data, existing LCU benchmarks for LLMs often result in prohibitively…

Computation and Language · Computer Science 2025-07-31 Zhongzhan Huang , Guoming Ling , Shanshan Zhong , Hefeng Wu , Liang Lin

In this paper, we review the literature on statistical long-range correlation in DNA sequences. We examine the current evidence for these correlations, and conclude that a mixture of many length scales (including some relatively long ones)…

chao-dyn · Physics 2009-10-22 Wentian Li , Thomas G. Marr , Kunihiko Kaneko

A hypercomplex representation of DNA is proposed to facilitate comparison of DNA sequences with fuzzy composition. Using hypercomplex number representation, conventional sequence analysis method, such as, dot matrix analysis, dynamic…

Quantitative Methods · Quantitative Biology 2023-08-03 Jian-Jun Shu , Yajing Li

Bidirectional Long Short-Term Memory (LSTM) is a special kind of Recurrent Neural Network (RNN) architecture which is designed to model sequences and their long-range dependencies more precisely than RNNs. This paper proposes to use deep…

Machine Learning · Computer Science 2020-04-07 Neda Tavakoli

For a set of mulitple sequences, their patterns,Longest Common Subsequences (LCS) and Shortest Common Supersequences (SCS) represent different aspects of these sequences profile, and they can all be used for biological sequence comparisons…

Data Structures and Algorithms · Computer Science 2016-11-17 Kang Ning , Hoong Kee Ng , Hon Wai Leong

The classification of DNA sequences is a key research area in bioinformatics as it enables researchers to conduct genomic analysis and detect possible diseases. In this paper, three state-of-the-art algorithms, namely Convolutional Neural…

Other Quantitative Biology · Quantitative Biology 2020-11-03 Xiangxie Zhang , Ben Beinke , Berlian Al Kindhi , Marco Wiering

Several biological problems require the identification of regions in a sequence where some feature occurs within a target density range: examples including the location of GC-rich regions, identification of CpG islands, and sequence…

Data Structures and Algorithms · Computer Science 2013-08-15 Benjamin A. Burton , Mathias Hiron

Educators evaluate student knowledge using knowledge component (KC) models that map assessment questions to KCs. Still, designing KC models for large question banks remains an insurmountable challenge for instructors who need to analyze…

Artificial Intelligence · Computer Science 2025-09-19 Yumou Wei , Paulo Carvalho , John Stamper

Genome assembly using high throughput data with short reads, arguably, remains an unresolvable task in repetitive genomes, since when the length of a repeat exceeds the read length, it becomes difficult to unambiguously connect the flanking…

Quantitative Methods · Quantitative Biology 2013-07-31 Viraj Deshpande , Eric DK Fung , Son Pham , Vineet Bafna

Clustering high-dimensional data is a critical challenge in machine learning due to the curse of dimensionality and the presence of noise. Traditional clustering algorithms often fail to capture the intrinsic structures in such data. This…

Machine Learning · Computer Science 2025-03-21 Joanikij Chulev , Angela Mladenovska

By using the Jensen-Shannon divergence, genomic DNA can be divided into compositionally distinct domains through a standard recursive segmentation procedure. Each domain, while significantly different from its neighbours, may however share…

Biological Physics · Physics 2009-11-07 Rajeev K. Azad , J. Subba Rao , Wentian Li , Ramakrishna Ramaswamy

Sparse code multiple access (SCMA) is a new multiple access technique which supports massive connectivity. Compared with the current Long Term Evolution (LTE) system, it enables the overloading of active users on limited orthogonal…

Information Theory · Computer Science 2016-11-29 Chenchen Zhang , Yuan Luo , Yan Chen

Motivation: With the development of third-generation sequencing technologies, people are able to obtain DNA sequences with lengths from 10s to 100s of kb. These long reads allow protein domain annotation without assembly, thus can produce…

Genomics · Quantitative Biology 2021-07-09 Du Nan , Jiayu Shang , Yanni Sun

Synthetic datasets constructed from formal languages allow fine-grained examination of the learning and generalization capabilities of machine learning systems for sequence classification. This article presents a new benchmark for machine…

Reconciling gene trees with a species tree is a fundamental problem to understand the evolution of gene families. Many existing approaches reconcile each gene tree independently. However, it is well-known that the evolution of gene families…

Populations and Evolution · Quantitative Biology 2018-06-12 Riccardo Dondi , Manuel Lafond , Celine Scornavacca

We investigate regression for variable length sequential data containing missing samples and introduce a novel tree architecture based on the Long Short-Term Memory (LSTM) networks. In our architecture, we employ a variable number of LSTM…

Machine Learning · Computer Science 2020-05-26 S. Onur Sahin , Suleyman S. Kozat

Code complexity metrics such as cyclomatic complexity have long been used to assess software quality and maintainability. With the rapid advancement of large language models (LLMs) on coding tasks, an important yet underexplored question…

Software Engineering · Computer Science 2026-05-28 Chen Xie , Xiaodong Gu , Yuling Shi , Beijun Shen

Consider two independent random strings having same length and taking values uniformly in a common finite alphabet. We study the order of the variance of the length of the longest common subsequences (LCS) of these strings when long blocks,…

Probability · Mathematics 2016-09-26 S. Amsalu , C. Houdré , H. Matzinger

Kernel segmentation aims at partitioning a data sequence into several non-overlapping segments that may have nonlinear and complex structures. In general, it is formulated as a discrete optimization problem with combinatorial constraints. A…

Machine Learning · Computer Science 2022-06-23 Tung Doan , Atsuhiro Takasu

We consider a novel approach of measuring the homology of DNA sequences based of the variety of optimal alignments in the longest common subsequence sense. The proposed approach is compared with BLAST in measuring the homology of four…

Applications · Statistics 2012-10-16 Erik Hirmo , Jüri Lember , Heinrich Matzinger