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Large Language Model (LLM)-based scientific agents have accelerated scientific discovery, yet they often suffer from significant inefficiencies due to adherence to fixed initial priors. Existing approaches predominantly operate within a…

Machine Learning · Computer Science 2026-02-09 Yingming Pu , Tao Lin , Hongyu Chen

We develop Structured-Knowledge-Informed Neural Networks (SKINNs), a unified estimation framework that embeds theoretical, simulated, previously learned, or cross-domain insights as differentiable constraints within flexible neural function…

Machine Learning · Statistics 2026-04-02 Yi Cao , Zexun Chen , Lin William Cong , Heqing Shi

As data-driven modeling of physical dynamical systems becomes more prevalent, a new challenge is emerging: making these models more compatible and aligned with existing human knowledge. AI-driven scientific modeling processes typically…

Machine Learning · Computer Science 2024-10-11 Kevin Zhang , Hod Lipson

Data is a critical element in any discovery process. In the last decades, we observed exponential growth in the volume of available data and the technology to manipulate it. However, data is only practical when one can structure it for a…

In recent years, the researches about solving partial differential equations (PDEs) based on artificial neural network have attracted considerable attention. In these researches, the neural network models are usually designed depend on…

Neural and Evolutionary Computing · Computer Science 2024-05-21 Bo Zhang , Chao Yang

In this work, we demonstrate how physical principles -- such as symmetries, invariances, and conservation laws -- can be integrated into the dynamic mode decomposition (DMD). DMD is a widely-used data analysis technique that extracts…

Dynamical Systems · Mathematics 2021-12-09 Peter J. Baddoo , Benjamin Herrmann , Beverley J. McKeon , J. Nathan Kutz , Steven L. Brunton

The prevailing model for disseminating scientific knowledge relies on individual publications dispersed across numerous journals and archives. This legacy system is ill suited to the recent exponential proliferation of publications,…

The advent of big data has vast potential for discovery in natural phenomena ranging from climate science to medicine, but overwhelming complexity stymies insight. Existing theory is often not able to succinctly describe salient phenomena,…

Machine Learning · Computer Science 2021-06-25 Bryan E. Kaiser , Juan A. Saenz , Maike Sonnewald , Daniel Livescu

Pharmacometric models are pivotal across drug discovery and development, playing a decisive role in determining the progression of candidate molecules. However, the derivation of mathematical equations governing the system is a…

Machine Learning · Computer Science 2024-05-02 Imran Nasim , Adam Nasim

With the expansion of scientific research, the number of scientific research is increasing. A new urgent problem is raised that how to keep these researches in a proper way. Therefore, knowledge mapping methods come into being, providing a…

Digital Libraries · Computer Science 2022-02-22 Fan Shen

Physics-informed neural networks (PINNs), rooted in deep learning, have emerged as a promising approach for solving partial differential equations (PDEs). By embedding the physical information described by PDEs into feedforward neural…

Machine Learning · Computer Science 2024-01-26 Yanzhi Liu , Ruifan Wu , Ying Jiang

High-dimensional design spaces underpin a wide range of physics-based modeling and computational design tasks in science and engineering. These problems are commonly formulated as constrained black-box searches over rugged objective…

Machine Learning · Computer Science 2026-01-13 Suvo Banik , Troy D. Loeffler , Henry Chan , Sukriti Manna , Orcun Yildiz , Tom Peterka , Subramanian Sankaranarayanan

Form-finding of unilateral membrane structures is commonly addressed by solving equilibrium equations with Finite Element Methods (FEMs). This paper investigates Physics-Informed Neural Networks (PINNs) as an alternative, where the…

Computational Engineering, Finance, and Science · Computer Science 2026-05-05 Luigi Sibille , Sigrid Adriaenssens , Carlo Olivieri

Discovering governing equations from observational data remains a fundamental challenge in scientific modeling, particularly when the underlying mathematical structure is unknown. Traditional sparse identification methods like SINDy excel…

Machine Learning · Computer Science 2026-05-12 Mohammad Amin Basiri , Charles Nicholson

Machine learning has emerged as a transformative tool for solving differential equations (DEs), yet prevailing methodologies remain constrained by dual limitations: data-driven methods demand costly labeled datasets while model-driven…

Machine Learning · Computer Science 2026-01-01 Heng Wu , Benzhuo Lu

A complete understanding of physical systems requires models that are accurate and obeys natural conservation laws. Recent trends in representation learning involve learning Lagrangian from data rather than the direct discovery of governing…

Machine Learning · Statistics 2023-02-10 Tapas Tripura , Souvik Chakraborty

This work addresses the development of a physics-informed neural network (PINN) with a loss term derived from a discretized time-dependent reduced-order system. In this work, first, the governing equations are discretized using a finite…

Numerical Analysis · Mathematics 2024-01-30 Rahul Halder , Giovanni Stabile , Gianluigi Rozza

Despite the fact that our physical observations can often be described by derived physical laws, such as the wave equation, in many cases, we observe data that do not match the laws or have not been described physically yet. Therefore…

Geophysics · Physics 2023-09-26 Shijun Cheng , Tariq Alkhalifah

We propose an efficient thermodynamics-informed latent space dynamics identification (tLaSDI) framework for the reduced-order modeling of parametric nonlinear dynamical systems. This framework integrates autoencoders for dimensionality…

Machine Learning · Computer Science 2025-06-11 Xiaolong He , Yeonjong Shin , Anthony Gruber , Sohyeon Jung , Kookjin Lee , Youngsoo Choi

A quantum algorithm for general combinatorial search that uses the underlying structure of the search space to increase the probability of finding a solution is presented. This algorithm shows how coherent quantum systems can be matched to…

Quantum Physics · Physics 2009-10-30 Tad Hogg
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