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Quantification of anatomical shape changes currently relies on scalar global indexes which are largely insensitive to regional or asymmetric modifications. Accurate assessment of pathology-driven anatomical remodeling is a crucial step for…

Adversarial training (AT) is widely considered the state-of-the-art technique for improving the robustness of deep neural networks (DNNs) against adversarial examples (AE). Nevertheless, recent studies have revealed that adversarially…

Machine Learning · Computer Science 2023-08-04 Chenhao Lin , Xiang Ji , Yulong Yang , Qian Li , Chao Shen , Run Wang , Liming Fang

Accurate and interpretable mortality risk prediction in intensive care units (ICUs) remains a critical challenge due to the irregular temporal structure of electronic health records (EHRs), the complexity of longitudinal disease…

Machine Learning · Computer Science 2026-03-10 Zahra Jafari , Azadeh Zamanifar , Amirfarhad Farhadi

With an increasing focus on precision medicine in medical research, numerous studies have been conducted in recent years to clarify the relationship between treatment effects and patient characteristics. The treatment effects for patients…

Methodology · Statistics 2023-09-22 Ke Wan , Kensuke Tanioka , Toshio Shimokawa

Alzheimer's disease (AD) has a complex and multifactorial etiology, which requires integrating information about neuroanatomy, genetics, and cerebrospinal fluid biomarkers for accurate diagnosis. Hence, recent deep learning approaches…

Machine Learning · Computer Science 2023-03-15 Tom Nuno Wolf , Sebastian Pölsterl , Christian Wachinger

Early detection of Alzheimer's disease (AD) is crucial because its neurodegenerative effects are irreversible, and neuropathologic and social-behavioral risk factors accumulate years before diagnosis. Identifying higher-risk individuals…

Machine Learning · Computer Science 2025-10-14 Xi Mao , Zhendong Wang , Jingyu Li , Lingchao Mao , Utibe Essien , Hairong Wang , Xuelei Sherry Ni

In the context of human-in-the-loop Machine Learning applications, like Decision Support Systems, interpretability approaches should provide actionable insights without making the users wait. In this paper, we propose Accelerated…

Machine Learning · Computer Science 2021-12-24 David Dandolo , Chiara Masiero , Mattia Carletti , Davide Dalle Pezze , Gian Antonio Susto

Hereby we propose a Bayesian method of estimation for the semiparametric Additive Hazards Model (AHM) from Survival Analysis under right-censoring. With this aim, we review the AHM revisiting the likelihood function, so as to comment on the…

Methodology · Statistics 2025-05-28 Enrique Ernesto Álvarez , Maximiliano Luis Riddick

Deep learning excels in the analysis of unstructured data and recent advancements allow to extend these techniques to survival analysis. In the context of clinical radiology, this enables, e.g., to relate unstructured volumetric images to a…

Machine Learning · Computer Science 2021-11-04 Tobias Weber , Michael Ingrisch , Matthias Fabritius , Bernd Bischl , David Rügamer

It has been observed that deep neural networks (DNNs) often use both genuine as well as spurious features. In this work, we propose "Amending Inherent Interpretability via Self-Supervised Masking" (AIM), a simple yet interestingly effective…

Computer Vision and Pattern Recognition · Computer Science 2025-08-18 Eyad Alshami , Shashank Agnihotri , Bernt Schiele , Margret Keuper

Survival analysis is a cornerstone of clinical research by modeling time-to-event outcomes such as metastasis, disease relapse, or patient death. Unlike standard tabular data, survival data often come with incomplete event information due…

Machine Learning · Computer Science 2026-02-06 Marie Brockschmidt , Maresa Schröder , Stefan Feuerriegel

Sparse additive models have attracted much attention in high-dimensional data analysis due to their flexible representation and strong interpretability. However, most existing models are limited to single-level learning under the…

Machine Learning · Computer Science 2026-04-23 Xuelin Zhang , Xinyue Liu , Lingjuan Wu , Hong Chen

Mediation analysis is a useful tool to evaluate surrogate endpoints in clinical trials. We propose a novel method, the M-survival learner, for estimating heterogeneous indirect treatment effects in the presence of censored outcomes. The…

Methodology · Statistics 2026-04-16 Xingyu Li , Qing Liu , Xun Jiang , Hong Amy Xia , Brian P. Hobbs , Peng Wei

As in many fields of medical research, survival analysis has witnessed a growing interest in the application of deep learning techniques to model complex, high-dimensional, heterogeneous, incomplete, and censored medical data. Current…

Machine Learning · Computer Science 2023-12-25 Patricia A. Apellániz , Juan Parras , Santiago Zazo

Interpretability is one of the considerations when applying machine learning to high-stakes fields such as healthcare that involve matters of life safety. Generalized Additive Models (GAMs) enhance interpretability by visualizing shape…

Machine Learning · Computer Science 2025-10-06 Fumin Wang

We study explained variation under the additive hazards regression model for right-censored data. We consider different approaches for developing such a measure, and focus on one that estimates the proportion of variation in the failure…

Applications · Statistics 2020-09-02 Denise Rava , Ronghui Xu

Non-homogeneous hidden Markov models (NHHMM) are a subclass of dependent mixture models used for semi-supervised learning, where both transition probabilities between the latent states and mean parameter of the probability distribution of…

Machine Learning · Statistics 2019-12-23 Aliaksandr Hubin

Accurate short-range prediction of extreme air temperature events remains a fundamental challenge in operational climate-risk management. We present Multi-Modal Weather State Transition Model with Anomaly-Driven Recurrent Attention Network…

Machine Learning · Computer Science 2025-11-18 Shaheen Mohammed Saleh Ahmed , Hakan Hakan Guneyli

Random effect models for time-to-event data, also known as frailty models, provide a conceptually appealing way of quantifying association between survival times and of representing heterogeneities resulting from factors which may be…

Methodology · Statistics 2024-06-04 Maximilian Bardo , Niel Hens , Steffen Unkel

Survival analysis is a critical tool for the modelling of time-to-event data, such as life expectancy after a cancer diagnosis or optimal maintenance scheduling for complex machinery. However, current neural network models provide an…

Machine Learning · Statistics 2021-12-06 Fabio Luis de Mello , J Mark Wilkinson , Visakan Kadirkamanathan
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