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Hypertension and atrial fibrillation (AF) often coexist in critically ill patients, significantly increasing mortality rates in the ICU. Early identification of high-risk individuals is crucial for targeted interventions. However, limited…

Applications · Statistics 2025-06-19 Shuheng Chen , Yong Si , Junyi Fan , Li Sun , Greg Placencia , Elham Pishgar , Kamiar Alaei , Maryam Pishgar

Agent-Based Models are a powerful class of computational models widely used to simulate complex phenomena in many different application areas. However, one of the most critical aspects, poorly investigated in the literature, regards an…

Quantitative Methods · Quantitative Biology 2021-03-02 Cristina Curreli , Francesco Pappalardo , Giulia Russo , Marzio Pennisi , Dimitrios Kiagias , Miguel Juarez , Marco Viceconti , .

Agent-based models (ABMs) are proliferating as decision-making tools across policy areas in transportation, economics, and epidemiology. In these models, a central object of interest is the discrete origin-destination matrix which captures…

Machine Learning · Computer Science 2025-05-12 Ioannis Zachos , Mark Girolami , Theodoros Damoulas

The integration of Large Language Models (LLMs) into healthcare is constrained by knowledge limitations, hallucinations, and a disconnect from Evidence-Based Medicine (EBM). While Retrieval-Augmented Generation (RAG) offers a solution,…

Computation and Language · Computer Science 2026-02-03 Qiaoyu Zheng , Yuze Sun , Chaoyi Wu , Weike Zhao , Pengcheng Qiu , Yongguo Yu , Kun Sun , Jian Zhang , Yanfeng Wang , Ya Zhang , Weidi Xie

The rise of Large Language Models (LLMs) has enabled the development of specialized AI agents with domain-specific reasoning and interaction capabilities, particularly in healthcare. While recent frameworks simulate medical decision-making,…

Artificial Intelligence · Computer Science 2025-07-04 Tianqi Shang , Weiqing He , Charles Zheng , Lingyao Li , Li Shen , Bingxin Zhao

Non-pharmaceutical interventions (NPIs) are commonly used tools for controlling infectious disease transmission when pharmaceutical options are unavailable. Yet, identifying effective interventions that minimize societal disruption remains…

Multiagent Systems · Computer Science 2026-04-03 Anja Wolpers , Johannes Ponge , Adelinde M. Uhrmacher

Detecting complex interactions among risk factors in case-control studies is a fundamental task in clinical and population research. However, though hypothesis testing using logistic regression (LR) is a convenient solution, the LR…

Methodology · Statistics 2015-02-11 Guoqiang Yu , David J. Miller , Carl D. Langefeld , David M. Herrington , Yue Wang

Multimodal Large Language Models (MLLMs) are evolving from passive observers into active agents, solving problems through Visual Expansion (invoking visual tools) and Knowledge Expansion (open-web search). However, existing evaluations fall…

Artificial Intelligence · Computer Science 2026-04-06 Qianshan Wei , Yishan Yang , Siyi Wang , Jinglin Chen , Binyu Wang , Jiaming Wang , Shuang Chen , Zechen Li , Yang Shi , Yuqi Tang , Weining Wang , Yi Yu , Chaoyou Fu , Qi Li , Yi-Fan Zhang

This paper presents an innovative large language model (LLM) agent framework for enhancing diagnostic accuracy in simulated clinical environments using the AgentClinic benchmark. The proposed automatic correction enables doctor agents to…

Artificial Intelligence · Computer Science 2024-10-15 Abhishek Dutta , Yen-Che Hsiao

Globally, the outbreaks of infectious diseases have exerted an extremely profound and severe influence on health security and the economy. During the critical phases of epidemics, devising effective intervention measures poses a significant…

Machine Learning · Computer Science 2025-05-08 Baida Zhang , Yakai Chen , Huichun Li , Zhenghu Zu

Real-world image restoration (IR) is inherently complex and often requires combining multiple specialized models to address diverse degradations. Inspired by human problem-solving, we propose AgenticIR, an agentic system that mimics the…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Kaiwen Zhu , Jinjin Gu , Zhiyuan You , Yu Qiao , Chao Dong

Large transformer models, trained on diverse datasets, have demonstrated impressive few-shot performance on previously unseen tasks without requiring parameter updates. This capability has also been explored in Reinforcement Learning (RL),…

Multiagent Systems · Computer Science 2026-04-02 Tao Jiang , Zichuan Lin , Lihe Li , Yi-Chen Li , Cong Guan , Lei Yuan , Zongzhang Zhang , Yang Yu , Deheng Ye

Advances in deep learning (DL)-based models for brain image analysis have significantly enhanced the accuracy of Alzheimer's disease (AD) diagnosis, allowing for more timely interventions. Despite these advancements, most current DL models…

Image and Video Processing · Electrical Eng. & Systems 2024-10-18 Yooseung Shin , Kwanseok Oh , Heung-Il Suk

Agentic AI require persistent memory to store user-specific histories beyond the limited context window of LLMs. Existing memory systems use dense vector databases or knowledge-graph traversal (or hybrid), incurring high retrieval latency…

Artificial Intelligence · Computer Science 2026-02-17 Yi Li , Lianjie Cao , Faraz Ahmed , Puneet Sharma , Bingzhe Li

Alzheimer's Disease (AD) is characterized by a cascade of biomarkers becoming abnormal, the pathophysiology of which is very complex and largely unknown. Event-based modeling (EBM) is a data-driven technique to estimate the sequence in…

Machine Learning · Computer Science 2019-08-14 Vikram Venkatraghavan , Esther E. Bron , Wiro J. Niessen , Stefan Klein

Edge-based multimodal medical monitoring requires models that balance diagnostic accuracy with severe energy constraints. Continuous acquisition of ECG, PPG, EMG, and IMU streams rapidly drains wearable batteries, often limiting operation…

Emerging Technologies · Computer Science 2026-04-14 Chengwei Zhou , Zhaoyan Jia , Haotian Yu , Xuming Chen , Brandon Lee , Christopher Pulliam , Steve Majerus , Massoud Pedram , Gourav Datta

Agent-Based Models (ABMs) are used in several fields to study the evolution of complex systems from micro-level assumptions. However, ABMs typically can not estimate agent-specific (or "micro") variables: this is a major limitation which…

Physics and Society · Physics 2022-11-24 Corrado Monti , Marco Pangallo , Gianmarco De Francisci Morales , Francesco Bonchi

Network models are increasingly used to study infectious disease spread. Exponential Random Graph models have a history in this area, with scalable inference methods now available. An alternative approach uses mechanistic network models.…

Methodology · Statistics 2024-01-11 Octavious Smiley , Till Hoffmann , Jukka-Pekka Onnela

Artificial intelligence(AI)-assisted method had received much attention in the risk field such as disease diagnosis. Different from the classification of disease types, it is a fine-grained task to classify the medical images as benign or…

Computer Vision and Pattern Recognition · Computer Science 2022-06-10 Shuang Ge , Kehong Yuan , Maokun Han , Desheng Sun , Huabin Zhang , Qiongyu Ye

Agentic AI is rapidly advancing in healthcare and biomedical research. However, in medical image analysis, their performance and adoption remain limited due to the lack of a robust ecosystem, insufficient toolsets, and the absence of…

Computer Vision and Pattern Recognition · Computer Science 2025-09-25 Songhao Li , Jonathan Xu , Tiancheng Bao , Yuxuan Liu , Yuchen Liu , Yihang Liu , Lilin Wang , Wenhui Lei , Sheng Wang , Yinuo Xu , Yan Cui , Jialu Yao , Shunsuke Koga , Zhi Huang