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The COVID-19 pandemic has highlighted the importance of in-silico epidemiological modelling in predicting the dynamics of infectious diseases to inform health policy and decision makers about suitable prevention and containment strategies.…

This study demonstrates the implementation of the stochastic ruler discrete simulation optimization method for calibrating an agent-based model (ABM) developed to simulate hepatitis C virus (HCV) transmission. The ABM simulates HCV…

Systems and Control · Electrical Eng. & Systems 2022-03-04 Soham Das , Navonil Mustafee , Varun Ramamohan

Agent-based modelling (ABM) is a widespread approach to simulate complex systems. Advancements in computational processing and storage have facilitated the adoption of ABMs across many fields; however, ABMs face challenges that limit their…

Machine Learning · Computer Science 2026-03-06 M Lopes Alves , Joel Dyer , Doyne Farmer , Michael Wooldridge , Anisoara Calinescu

This paper presents a hybrid modeling approach that couples an Agent-Based Model (ABM) with a partial differential equation (PDE) model in an epidemic setting to simulate the spatial spread of infectious diseases using a compartmental…

Multiagent Systems · Computer Science 2026-01-21 Kristina Kehrer , Tim O. F. Conrad

Running agent-based models (ABMs) is a burdensome computational task, specially so when considering the flexibility ABMs intrinsically provide. This paper uses a bundle of model configuration parameters along with obtained results from a…

Multiagent Systems · Computer Science 2020-01-14 Bernardo Alves Furtado

Agentic artificial intelligence (AI) -- multi-agent systems that combine large language models with external tools and autonomous planning -- are rapidly transitioning from research laboratories into high-stakes domains. Our earlier "Basic"…

Artificial Intelligence · Computer Science 2025-09-16 Manish Shukla

Agent-based simulation is crucial for modeling complex human behavior, yet traditional approaches require extensive domain knowledge and large datasets. In data-scarce healthcare settings where historic and counterfactual data are limited,…

Artificial Intelligence · Computer Science 2025-04-01 Sarah Martinson , Lingkai Kong , Cheol Woo Kim , Aparna Taneja , Milind Tambe

Machine learning and deep learning methods have become essential for computer-assisted prediction in medicine, with a growing number of applications also in the field of mammography. Typically these algorithms are trained for a specific…

Image and Video Processing · Electrical Eng. & Systems 2021-12-03 Maria Wimmer , Gert Sluiter , David Major , Dimitrios Lenis , Astrid Berg , Theresa Neubauer , Katja Bühler

This study presents a neural network-enhanced approach to modeling disease spread dynamics over time and space. Neural networks are used to estimate time-varying parameters, with two calibration methods explored: Approximate Bayesian…

Quantitative Methods · Quantitative Biology 2024-10-29 Randy L. Caga-anan

Intensive care clinicians need reliable clinical practice tools to preempt unexpected critical events that might harm their patients in intensive care units (ICU), to pre-plan timely interventions, and to keep the patient's family well…

We introduce Agentic Economic Modeling (AEM), a framework that aligns synthetic LLM choices with small-sample human evidence for reliable econometric inference. AEM first generates task-conditioned synthetic choices via LLMs, then learns a…

In this paper, we consider the problem of reference tracking in uncertain nonlinear systems. A neural State-Space Model (NSSM) is used to approximate the nonlinear system, where a deep encoder network learns the nonlinearity from data, and…

Systems and Control · Electrical Eng. & Systems 2026-02-26 Jiaqi Yan , Ankush Chakrabarty , Alisa Rupenyan , John Lygeros

Large Language Models (LLMs) offer new opportunities to accelerate complex interdisciplinary research domains. Epidemic modeling, characterized by its complexity and reliance on network science, dynamical systems, epidemiology, and…

Social and Information Networks · Computer Science 2026-02-26 Mohammad Hossein Samaei , Faryad Darabi Sahneh , Lee W. Cohnstaedt , Caterina Scoglio

Deep learning methods based on Convolutional Neural Networks (CNNs) have shown great potential to improve early and accurate diagnosis of Alzheimer's disease (AD) dementia based on imaging data. However, these methods have yet to be widely…

Computer Vision and Pattern Recognition · Computer Science 2025-01-22 Wenjie Kang , Lize Jiskoot , Peter De Deyn , Geert Biessels , Huiberdina Koek , Jurgen Claassen , Huub Middelkoop , Wiesje Flier , Willemijn J. Jansen , Stefan Klein , Esther Bron

The application of artificial intelligence (AI) in medical imaging has revolutionized diagnostic practices, enabling advanced analysis and interpretation of radiological data. This study presents a comprehensive evaluation of…

Image and Video Processing · Electrical Eng. & Systems 2025-07-22 Zhijin He , Alan B. McMillan

Alzheimer's Disease Analysis Model (ADAM) is a multi-agent reasoning large language model (LLM) framework designed to integrate and analyze multimodal data, including microbiome profiles, clinical datasets, and external knowledge bases, to…

Artificial Intelligence · Computer Science 2025-08-22 Ziyuan Huang , Vishaldeep Kaur Sekhon , Roozbeh Sadeghian , Maria L. Vaida , Cynthia Jo , Doyle Ward , Vanni Bucci , John P. Haran

It has been observed that deep neural networks (DNNs) often use both genuine as well as spurious features. In this work, we propose "Amending Inherent Interpretability via Self-Supervised Masking" (AIM), a simple yet interestingly effective…

Computer Vision and Pattern Recognition · Computer Science 2025-08-18 Eyad Alshami , Shashank Agnihotri , Bernt Schiele , Margret Keuper

An increasing number of emerging applications, e.g., internet of things, vehicular communications, augmented reality, and the growing complexity due to the interoperability requirements of these systems, lead to the need to change the tools…

Multiagent Systems · Computer Science 2019-01-16 Merim Dzaferagic , M. Majid Butt , Maria Murphy , Nicholas Kaminski , Nicola Marchetti

Simultaneously optimizing multiple, frequently conflicting, molecular properties is a key bottleneck in the development of novel therapeutics. Although a promising approach, the efficacy of multi-task learning is often compromised by…

Machine Learning · Computer Science 2025-10-01 Mason Minot , Gisbert Schneider

Effective pandemic control requires timely and coordinated policymaking across administrative regions that are intrinsically interdependent. However, human-driven responses are often fragmented and reactive, with policies formulated in…

Artificial Intelligence · Computer Science 2026-01-15 Ziyi Shi , Xusen Guo , Hongliang Lu , Mingxing Peng , Haotian Wang , Zheng Zhu , Zhenning Li , Yuxuan Liang , Xinhu Zheng , Hai Yang