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Diffusion models are important in tissue engineering as they enable an understanding of molecular delivery to cells in tissue constructs. As three-dimensional (3D) tissue constructs become larger, more intricate, and more clinically…

Tissues and Organs · Quantitative Biology 2015-12-22 Richard J. McMurtrey

In the paper, we present an approach for learning a single model that universally segments 33 anatomical structures, including vertebrae, pelvic bones, and abdominal organs. Our model building has to address the following challenges.…

Image and Video Processing · Electrical Eng. & Systems 2022-03-07 Pengbo Liu , Yang Deng , Ce Wang , Yuan Hui , Qian Li , Jun Li , Shiwei Luo , Mengke Sun , Quan Quan , Shuxin Yang , You Hao , Honghu Xiao , Chunpeng Zhao , Xinbao Wu , S. Kevin Zhou

Machine learning has significantly advanced healthcare by aiding in disease prevention and treatment identification. However, accessing patient data can be challenging due to privacy concerns and strict regulations. Generating synthetic,…

Purpose: Accurate 3D hand pose estimation supports surgical applications such as skill assessment, robot-assisted interventions, and geometry-aware workflow analysis. However, surgical environments pose severe challenges, including intense…

Recent synthetic 3D human datasets for the face, body, and hands have pushed the limits on photorealism. Face recognition and body pose estimation have achieved state-of-the-art performance using synthetic training data alone, but for the…

Computer Vision and Pattern Recognition · Computer Science 2025-03-26 Zhuoran Zhao , Linlin Yang , Pengzhan Sun , Pan Hui , Angela Yao

In recent years, human in silico trials have gained significant traction as a powerful approach to evaluate the effects of drugs, clinical interventions, and medical devices. In silico trials not only minimise patient risks but also reduce…

Computational Engineering, Finance, and Science · Computer Science 2025-03-06 Ruben Doste , Julia Camps , Zhinuo Jenny Wang , Lucas Arantes Berg , Maxx Holmes , Hannah Smith , Marcel Beetz , Lei Li , Abhirup Banerjee , Vicente Grau , Blanca Rodriguez

Peritoneal dialysis (PD) is becoming more popular as a result of a rising interest in home dialysis, lower intrusion in social life and longer preservation of residual kidney function. However, PD has several important drawbacks: small…

Quantitative Methods · Quantitative Biology 2025-02-20 Sangita Swapnasrita , Joost C de Vries , Carl M Öberg , Aurélie MF Carlier , Karin GF Gerritsen

Progress in anatomical 3D shape classification is limited by the complexity of mesh data and the lack of standardized benchmarks, highlighting the need for robust learning methods and reproducible evaluation. We introduce two key steps…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Tomáš Krsička , Tibor Kubík

We present 2 statistical models of the skull and mandible built upon an elastic registration method of 3D meshes. The aim of this work is to relate degrees of freedom of skull anatomy, as static relations are of main interest for…

Medical Physics · Physics 2016-08-16 Maxime Berar , Michel Desvignes , Gérard Bailly , Yohan Payan

To treat Trochlear Dysplasia (TD), current approaches rely mainly on low-resolution clinical Magnetic Resonance (MR) scans and surgical intuition. The surgeries are planned based on surgeons experience, have limited adoption of minimally…

Computer Vision and Pattern Recognition · Computer Science 2025-08-11 Michael Wehrli , Alicia Durrer , Paul Friedrich , Sidaty El Hadramy , Edwin Li , Luana Brahaj , Carol C. Hasler , Philippe C. Cattin

Unsafe surgical care is a critical health concern, often linked to limitations in surgeon experience, skills, and situational awareness. Integrating patient-specific 3D models into the surgical field can enhance visualization, provide…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Alberto Neri , Veronica Penza , Nazim Haouchine , Leonardo S. Mattos

Ultrasound computed tomography (USCT) is an emerging imaging modality for breast imaging that can produce quantitative images that depict the acoustic properties of tissues. Computer-simulation studies, also known as virtual imaging trials,…

Medical Physics · Physics 2022-06-24 Fu Li , Umberto Villa , Seonyeong Park , Mark A. Anastasio

One of the key impediments for developing and assessing robust medical imaging algorithms is limited access to large-scale datasets with suitable annotations. Synthetic data generated with plausible physical and biological constraints may…

Computer Vision and Pattern Recognition · Computer Science 2025-09-19 Christopher Wiedeman , Anastasiia Sarmakeeva , Elena Sizikova , Daniil Filienko , Miguel Lago , Jana G. Delfino , Aldo Badano

Deep generative models and synthetic medical data have shown significant promise in addressing key challenges in healthcare, such as privacy concerns, data bias, and the scarcity of realistic datasets. While research in this area has grown…

Machine Learning · Computer Science 2025-02-05 Krishan Agyakari Raja Babu , Supriti Mulay , Om Prabhu , Mohanasankar Sivaprakasam

We present a semi-parametric generative model for predicting anatomy of a patient in subsequent scans following a single baseline image. Such predictive modeling promises to facilitate novel analyses in both voxel-level studies and…

Computer Vision and Pattern Recognition · Computer Science 2020-10-13 Adrian V. Dalca , Ramesh Sridharan , Mert R. Sabuncu , Polina Golland

Although various 3D datasets with different functions and scales have been proposed recently, it remains challenging for individuals to complete the whole pipeline of large-scale data collection, sanitization, and annotation. Moreover, the…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Meida Chen , Qingyong Hu , Zifan Yu , Hugues Thomas , Andrew Feng , Yu Hou , Kyle McCullough , Fengbo Ren , Lucio Soibelman

The available reference data for the mandible and mandibular growth consists primarily of two-dimensional linear or angular measurements. The aim of this study was to create the first open-source, three-dimensional statistical shape model…

Our ability to produce human-scale bio-manufactured organs is critically limited by the need for vascularization and perfusion. For tissues of variable size and shape, including arbitrarily complex geometries, designing and printing…

Acquiring labeled datasets for 3D human mesh estimation is challenging due to depth ambiguities and the inherent difficulty of annotating 3D geometry from monocular images. Existing datasets are either real, with manually annotated 3D…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Lorenza Prospero , Orest Kupyn , Ostap Viniavskyi , João F. Henriques , Christian Rupprecht

In this paper, we define and study a new Cloth2Body problem which has a goal of generating 3D human body meshes from a 2D clothing image. Unlike the existing human mesh recovery problem, Cloth2Body needs to address new and emerging…

Computer Vision and Pattern Recognition · Computer Science 2023-09-29 Lu Dai , Liqian Ma , Shenhan Qian , Hao Liu , Ziwei Liu , Hui Xiong