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With the growing use of language models (LMs) in clinical environments, there is an immediate need to evaluate the accuracy and safety of LM-generated medical text. Currently, such evaluation relies solely on manual physician review.…

Large language models (LLMs) are increasingly envisioned as decision-support tools in clinical practice, yet safe clinical reasoning demands integrating heterogeneous knowledge bases -- trials, primary studies, regulatory documents, and…

Computation and Language · Computer Science 2025-05-22 Shan Chen , Pedro Moreira , Yuxin Xiao , Sam Schmidgall , Jeremy Warner , Hugo Aerts , Thomas Hartvigsen , Jack Gallifant , Danielle S. Bitterman

Evaluating the clinical correctness and reasoning fidelity of automatically generated medical imaging reports remains a critical yet unresolved challenge. Existing evaluation methods often fail to capture the structured diagnostic logic…

Artificial Intelligence · Computer Science 2026-01-26 Suzhong Fu , Jingqi Dong , Xuan Ding , Rui Sun , Yiming Yang , Shuguang Cui , Zhen Li

Deploying Large Language Models (LLMs) in medical applications requires fact-checking capabilities to ensure patient safety and regulatory compliance. We introduce MedFact, a challenging Chinese medical fact-checking benchmark with 2,116…

Computation and Language · Computer Science 2025-11-18 Jiayi He , Yangmin Huang , Qianyun Du , Xiangying Zhou , Zhiyang He , Jiaxue Hu , Xiaodong Tao , Lixian Lai

Large language models (LLMs) have excelled across domains, also delivering notable performance on the medical evaluation benchmarks, such as MedQA. However, there still exists a significant gap between the reported performance and the…

Computation and Language · Computer Science 2024-06-06 Yuxuan Zhou , Xien Liu , Chen Ning , Ji Wu

The rapid advancement of Large Language Models (LLMs) has stimulated interest in multi-agent collaboration for addressing complex medical tasks. However, the practical advantages of multi-agent collaboration approaches remain insufficiently…

Artificial Intelligence · Computer Science 2025-10-31 Yinghao Zhu , Ziyi He , Haoran Hu , Xiaochen Zheng , Xichen Zhang , Zixiang Wang , Junyi Gao , Liantao Ma , Lequan Yu

The advent of Large Language Models (LLMs) has significantly transformed the AI landscape, enhancing machine learning and AI capabilities. Factuality issue is a critical concern for LLMs, as they may generate factually incorrect responses.…

Computation and Language · Computer Science 2024-04-02 Xiaoze Liu , Feijie Wu , Tianyang Xu , Zhuo Chen , Yichi Zhang , Xiaoqian Wang , Jing Gao

The reliable evaluation of large language models (LLMs) in medical applications remains an open challenge, particularly in capturing the complexity of multi-turn doctor-patient interactions that unfold in real clinical environments.…

Artificial Intelligence · Computer Science 2025-10-15 Yuechun Yu , Han Ying , Haoan Jin , Wenjian Jiang , Dong Xian , Binghao Wang , Zhou Yang , Mengyue Wu

Large Language Models (LLMs) are increasingly applied to medicine, yet their adoption is limited by concerns over reliability and safety. Existing evaluations either test factual medical knowledge in isolation or assess patient-level…

Computation and Language · Computer Science 2026-05-08 Zhan Qu , Michael Färber

The automatic generation of medical reports utilizing Multimodal Large Language Models (MLLMs) frequently encounters challenges related to factual instability, which may manifest as the omission of findings or the incorporation of…

Computation and Language · Computer Science 2026-03-03 Cunyuan Yang , Dejuan Song , Xiaotao Pang , Qianqian Shen , Wenjie Nie , Yifan Huang , Lei Wu , Wei Han , Haishuai Wang , Jiajun Bu

Evaluating large language models (LLMs) in medicine is crucial because medical applications require high accuracy with little room for error. Current medical benchmarks have three main types: medical exam-based, comprehensive medical, and…

Critical appraisal of scientific literature is an essential skill in the biomedical field. While large language models (LLMs) can offer promising support in this task, their reliability remains limited, particularly for critical reasoning…

Computation and Language · Computer Science 2026-03-05 Doria Bonzi , Alexandre Guiggi , Frédéric Béchet , Carlos Ramisch , Benoit Favre

Despite the utility of Large Language Models (LLMs) across a wide range of tasks and scenarios, developing a method for reliably evaluating LLMs across varied contexts continues to be challenging. Modern evaluation approaches often use LLMs…

Computation and Language · Computer Science 2024-01-31 Steffi Chern , Ethan Chern , Graham Neubig , Pengfei Liu

Large Language Models (LLMs) are increasingly used for clinical decision support, where hallucinations and unsafe suggestions may pose direct risks to patient safety. These risks are hard to assess: subtle clinical errors are often missed…

Computation and Language · Computer Science 2026-05-14 Yinzhu Chen , Abdine Maiga , Hossein A. Rahmani , Emine Yilmaz

Methods to ensure factual accuracy of text generated by large language models (LLM) in clinical medicine are lacking. VeriFact is an artificial intelligence system that combines retrieval-augmented generation and LLM-as-a-Judge to verify…

Medical conversational AI (AI) plays a pivotal role in the development of safer and more effective medical dialogue systems. However, existing benchmarks and evaluation frameworks for assessing the information-gathering and diagnostic…

Computation and Language · Computer Science 2026-01-08 Lecheng Gong , Weimin Fang , Ting Yang , Dongjie Tao , Chunxiao Guo , Peng Wei , Bo Xie , Jinqun Guan , Zixiao Chen , Fang Shi , Jinjie Gu , Junwei Liu

Large language models (LLMs) are widely explored for reasoning-intensive research tasks, yet resources for testing whether they can infer scientific conclusions from structured biomedical evidence remain limited. We introduce…

Computation and Language · Computer Science 2026-04-09 Weiyue Li , Ruizhi Qian , Yi Li , Yongce Li , Yunfan Long , Jiahui Cai , Yan Luo , Mengyu Wang

In the medical domain, numerous scenarios necessitate the long-form generation ability of large language models (LLMs). Specifically, when addressing patients' questions, it is essential that the model's response conveys factual claims,…

Computation and Language · Computer Science 2024-10-16 Minbyul Jeong , Hyeon Hwang , Chanwoong Yoon , Taewhoo Lee , Jaewoo Kang

Evaluating the factuality of long-form generations from Large Language Models (LLMs) remains challenging due to efficiency bottlenecks and reliability concerns. Prior efforts attempt this by decomposing text into claims, searching for…

Computation and Language · Computer Science 2025-11-06 Yingjia Wan , Haochen Tan , Xiao Zhu , Xinyu Zhou , Zhiwei Li , Qingsong Lv , Changxuan Sun , Jiaqi Zeng , Yi Xu , Jianqiao Lu , Yinhong Liu , Zhijiang Guo

As large language models (LLMs) enter the medical domain, most benchmarks evaluate them on question answering or descriptive reasoning, overlooking quantitative reasoning critical to clinical decision-making. Existing datasets like…

Computation and Language · Computer Science 2025-11-03 Kangkun Mao , Jinru Ding , Jiayuan Chen , Mouxiao Bian , Ruiyao Chen , Xinwei Peng , Sijie Ren , Linyang Li , Jie Xu
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