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Segment Anything Model 2 (SAM 2), a prompt-driven foundation model extending SAM to both image and video domains, has shown superior zero-shot performance compared to its predecessor. Building on SAM's success in medical image segmentation,…

Computer Vision and Pattern Recognition · Computer Science 2025-02-06 Bin Xie , Hao Tang , Yan Yan , Gady Agam

Following the successful paradigm shift of large language models, leveraging pre-training on a massive corpus of data and fine-tuning on different downstream tasks, generalist models have made their foray into computer vision. The…

Image and Video Processing · Electrical Eng. & Systems 2025-11-21 Andrea Moglia , Matteo Leccardi , Matteo Cavicchioli , Alice Maccarini , Marco Marcon , Luca Mainardi , Pietro Cerveri

The Segment Anything Model (SAM) excels at generating precise object masks from input prompts but lacks semantic awareness, failing to associate its generated masks with specific object categories. To address this limitation, we propose…

Computer Vision and Pattern Recognition · Computer Science 2025-09-04 Rohit Kundu , Sudipta Paul , Arindam Dutta , Amit K. Roy-Chowdhury

Medical image segmentation is inherently uncertain. For a given image, there may be multiple plausible segmentation hypotheses, and physicians will often disagree on lesion and organ boundaries. To be suited to real-world application,…

Computer Vision and Pattern Recognition · Computer Science 2021-09-28 João Lourenço Silva , Arlindo L. Oliveira

With the emergence of the Segment Anything Model (SAM) as a foundational model for image segmentation, its application has been extensively studied across various domains, including the medical field. However, its potential in the context…

Computer Vision and Pattern Recognition · Computer Science 2023-10-17 SeungKyu Kim , Hyun-Jic Oh , Seonghui Min , Won-Ki Jeong

Quantifying aleatoric uncertainty in medical image segmentation is critical since it is a reflection of the natural variability observed among expert annotators. A conventional approach is to model the segmentation distribution using the…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Phi Van Nguyen , Ngoc Huynh Trinh , Duy Minh Lam Nguyen , Phu Loc Nguyen , Quoc Long Tran

Medical image segmentation plays a pivotal role in clinical diagnostics and treatment planning, yet existing models often face challenges in generalization and in handling both 2D and 3D data uniformly. In this paper, we introduce Medical…

Computer Vision and Pattern Recognition · Computer Science 2024-12-06 Jiayuan Zhu , Abdullah Hamdi , Yunli Qi , Yueming Jin , Junde Wu

Prompt-free image segmentation aims to generate accurate masks without manual guidance. Typical pre-trained models, notably Segmentation Anything Model (SAM), generate prompts directly at a single granularity level. However, this approach…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Qiyang Yu , Yu Fang , Tianrui Li , Xuemei Cao , Yan Chen , Jianghao Li , Fan Min , Yi Zhang

Image segmentation remains a pivotal component in medical image analysis, aiding in the extraction of critical information for precise diagnostic practices. With the advent of deep learning, automated image segmentation methods have risen…

Image and Video Processing · Electrical Eng. & Systems 2024-03-07 Nhat-Tan Bui , Dinh-Hieu Hoang , Minh-Triet Tran , Gianfranco Doretto , Donald Adjeroh , Brijesh Patel , Arabinda Choudhary , Ngan Le

The Segment Anything Model (SAM) is the first foundation model for general image segmentation. It has achieved impressive results on various natural image segmentation tasks. However, medical image segmentation (MIS) is more challenging…

Image and Video Processing · Electrical Eng. & Systems 2024-01-18 Yuhao Huang , Xin Yang , Lian Liu , Han Zhou , Ao Chang , Xinrui Zhou , Rusi Chen , Junxuan Yu , Jiongquan Chen , Chaoyu Chen , Sijing Liu , Haozhe Chi , Xindi Hu , Kejuan Yue , Lei Li , Vicente Grau , Deng-Ping Fan , Fajin Dong , Dong Ni

Is Segment Anything Model 3 (SAM3) capable in segmenting Any Pathology Images? Digital pathology segmentation spans tissue-level and nuclei-level scales, where traditional methods often suffer from high annotation costs and poor…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Qiuyu Kong , Shakiba Sharifi , Yiming Wang , Marco Cristani , Zanxi Ruan

Uncertainty quantification in medical images has become an essential addition to segmentation models for practical application in the real world. Although there are valuable developments in accurate uncertainty quantification methods using…

Image and Video Processing · Electrical Eng. & Systems 2023-05-02 Christiaan G. A. Viviers , Amaan M. M. Valiuddin , Peter H. N. de With , Fons van der Sommen

In this paper, we present PRISM, a Promptable and Robust Interactive Segmentation Model, aiming for precise segmentation of 3D medical images. PRISM accepts various visual inputs, including points, boxes, and scribbles as sparse prompts, as…

Computer Vision and Pattern Recognition · Computer Science 2024-04-24 Hao Li , Han Liu , Dewei Hu , Jiacheng Wang , Ipek Oguz

Segment Anything Model (SAM) has made great progress in anomaly segmentation tasks due to its impressive generalization ability. However, existing methods that directly apply SAM through prompting often overlook the domain shift issue,…

Computer Vision and Pattern Recognition · Computer Science 2024-12-30 Hui-Yue Yang , Hui Chen , Ao Wang , Kai Chen , Zijia Lin , Yongliang Tang , Pengcheng Gao , Yuming Quan , Jungong Han , Guiguang Ding

The unprecedented developments in segmentation foundational models have become a dominant force in the field of computer vision, introducing a multitude of previously unexplored capabilities in a wide range of natural images and videos.…

Computer Vision and Pattern Recognition · Computer Science 2024-08-26 Yichi Zhang , Zhenrong Shen

Medical image segmentation is crucial for computer-aided diagnosis, yet privacy constraints hinder data sharing across institutions. Federated learning addresses this limitation, but existing approaches often rely on lightweight…

Computer Vision and Pattern Recognition · Computer Science 2025-09-22 Tong Wang , Xingyue Zhao , Linghao Zhuang , Haoyu Zhao , Jiayi Yin , Yuyang He , Gang Yu , Bo Lin

Foundation models, such as the Segment Anything Model (SAM), have heightened interest in promptable zero-shot segmentation. Although these models perform strongly on natural images, their behavior on medical data remains insufficiently…

Image and Video Processing · Electrical Eng. & Systems 2026-04-07 Satrajit Chakrabarty , Ravi Soni

We propose a straightforward yet highly effective few-shot fine-tuning strategy for adapting the Segment Anything (SAM) to anatomical segmentation tasks in medical images. Our novel approach revolves around reformulating the mask decoder…

Computer Vision and Pattern Recognition · Computer Science 2024-07-08 Weiyi Xie , Nathalie Willems , Shubham Patil , Yang Li , Mayank Kumar

Leveraging the extensive training data from SA-1B, the Segment Anything Model (SAM) demonstrates remarkable generalization and zero-shot capabilities. However, as a category-agnostic instance segmentation method, SAM heavily relies on prior…

Computer Vision and Pattern Recognition · Computer Science 2023-11-30 Keyan Chen , Chenyang Liu , Hao Chen , Haotian Zhang , Wenyuan Li , Zhengxia Zou , Zhenwei Shi

The recent emergence of the Segment Anything Model (SAM) enables various domain-specific segmentation tasks to be tackled cost-effectively by using bounding boxes as prompts. However, in scene text segmentation, SAM can not achieve…

Computer Vision and Pattern Recognition · Computer Science 2024-12-31 Enze Xie , Jiaho Lyu , Daiqing Wu , Huawen Shen , Yu Zhou