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Discovering genes with similar functions across diverse biomedical contexts poses a significant challenge in gene representation learning due to data heterogeneity. In this study, we resolve this problem by introducing a novel model called…

Machine Learning · Computer Science 2023-10-05 Tianyu Liu , Yuge Wang , Rex Ying , Hongyu Zhao

Multimodal machine learning with missing modalities is an increasingly relevant challenge arising in various applications such as healthcare. This paper extends the current research into missing modalities to the low-data regime, i.e., a…

Machine Learning · Computer Science 2024-03-27 Zhuo Zhi , Ziquan Liu , Moe Elbadawi , Adam Daneshmend , Mine Orlu , Abdul Basit , Andreas Demosthenous , Miguel Rodrigues

Machine learning model bias can arise from dataset composition: correlated sensitive features can distort the downstream classification model's decision boundary and lead to performance differences along these features. Existing de-biasing…

Computer Vision and Pattern Recognition · Computer Science 2025-01-22 Miao Zhang , Zee fryer , Ben Colman , Ali Shahriyari , Gaurav Bharaj

Confounding bias is a key challenge in causal effect estimation from observational data. Double Machine Learning (DML) addresses this issue by estimating treatment and outcome nuisance functions, constructing treatment and outcome…

Machine Learning · Computer Science 2026-05-26 Guodu Xiang , Kui Yu , Yujie Wang , Richang Hong , Fuyuan Cao , Jiye Liang

Causal inference, estimating causal effects from observational data, is a fundamental tool in many disciplines. Of particular importance across a variety of domains is the continuous treatment setting, where the variable of intervention has…

Machine Learning · Computer Science 2026-05-15 Christopher Stith , Medha Barath , Vahid Balazadeh , Jesse C. Cresswell , Rahul G. Krishnan

Developing effective multimodal data fusion strategies has become increasingly essential for improving the predictive power of statistical machine learning methods across a wide range of applications, from autonomous driving to medical…

Machine Learning · Computer Science 2025-07-29 Ziyi Liang , Annie Qu , Babak Shahbaba

Reliably detecting diseases using relevant biological information is crucial for real-world applicability of deep learning techniques in medical imaging. We debias deep learning models during training against unknown bias - without…

Computer Vision and Pattern Recognition · Computer Science 2022-06-09 Simon Langer , Oliver Taubmann , Felix Denzinger , Andreas Maier , Alexander Mühlberg

Accurately measuring discrimination in machine learning-based automated decision systems is required to address the vital issue of fairness between subpopulations and/or individuals. Any bias in measuring discrimination can lead to either…

Machine Learning · Computer Science 2023-10-23 Rūta Binkytė , Sami Zhioua , Yassine Turki

We present a unified framework for studying the identifiability of representations learned from simultaneously observed views, such as different data modalities. We allow a partially observed setting in which each view constitutes a…

In multimodal learning, CLIP has emerged as the de-facto approach for mapping different modalities into a shared latent space by bringing semantically similar representations closer while pushing apart dissimilar ones. However, CLIP-based…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Eleonora Grassucci , Giordano Cicchetti , Danilo Comminiello

Machine learning methods often fail when deployed in the real world. Worse still, they fail in high-stakes situations and across socially sensitive lines. These issues have a chilling effect on the adoption of machine learning methods in…

Machine Learning · Computer Science 2025-09-05 Charles Jones , Ben Glocker

During the diagnostic process, clinicians leverage multimodal information, such as chief complaints, medical images, and laboratory-test results. Deep-learning models for aiding diagnosis have yet to meet this requirement. Here we report a…

Computer Vision and Pattern Recognition · Computer Science 2023-06-02 Hong-Yu Zhou , Yizhou Yu , Chengdi Wang , Shu Zhang , Yuanxu Gao , Jia Pan , Jun Shao , Guangming Lu , Kang Zhang , Weimin Li

We present modality gap, an intriguing geometric phenomenon of the representation space of multi-modal models. Specifically, we show that different data modalities (e.g. images and text) are embedded at arm's length in their shared…

Computation and Language · Computer Science 2022-10-21 Weixin Liang , Yuhui Zhang , Yongchan Kwon , Serena Yeung , James Zou

There are threefold challenges in emotion recognition. First, it is difficult to recognize human's emotional states only considering a single modality. Second, it is expensive to manually annotate the emotional data. Third, emotional data…

Signal Processing · Electrical Eng. & Systems 2018-08-08 Changde Du , Changying Du , Hao Wang , Jinpeng Li , Wei-Long Zheng , Bao-Liang Lu , Huiguang He

Machine learning models achieve state-of-the-art performance on many supervised learning tasks. However, prior evidence suggests that these models may learn to rely on shortcut biases or spurious correlations (intuitively, correlations that…

Machine Learning · Computer Science 2021-08-31 Sindhu C. M. Gowda , Shalmali Joshi , Haoran Zhang , Marzyeh Ghassemi

Multimodal representations and continual learning are two areas closely related to human intelligence. The former considers the learning of shared representation spaces where information from different modalities can be compared and…

Computer Vision and Pattern Recognition · Computer Science 2021-04-20 Kai Wang , Luis Herranz , Joost van de Weijer

Biases in the dataset often enable the model to achieve high performance on in-distribution data, while poorly performing on out-of-distribution data. To mitigate the detrimental effect of the bias on the networks, previous works have…

Computation and Language · Computer Science 2023-12-07 Eojin Jeon , Mingyu Lee , Juhyeong Park , Yeachan Kim , Wing-Lam Mok , SangKeun Lee

Confounding variables are a well known source of nuisance in biomedical studies. They present an even greater challenge when we combine them with black-box machine learning techniques that operate on raw data. This work presents two case…

Visual-language models have advanced the development of universal models, yet their application in medical imaging remains constrained by specific functional requirements and the limited data. Current general-purpose models are typically…

Computer Vision and Pattern Recognition · Computer Science 2024-10-08 Kaini Wang , Ling Yang , Siping Zhou , Guangquan Zhou , Wentao Zhang , Bin Cui , Shuo Li

Accurately predicting molecular properties is a challenging but essential task in drug discovery. Recently, many mono-modal deep learning methods have been successfully applied to molecular property prediction. However, the inherent…

Machine Learning · Computer Science 2024-09-16 Xiaohua Lu , Liangxu Xie , Lei Xu , Rongzhi Mao , Shan Chang , Xiaojun Xu
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