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Accurate medical symptom coding from unstructured clinical text, such as vaccine safety reports, is a critical task with applications in pharmacovigilance and safety monitoring. Symptom coding, as tailored in this study, involves…

Computation and Language · Computer Science 2025-04-07 Chengyang He , Wenlong Zhang , Violet Xinying Chen , Yue Ning , Ping Wang

Large language models (LLMs) have been applied to tasks in healthcare, ranging from medical exam questions to responding to patient questions. With increasing institutional partnerships between companies producing LLMs and healthcare…

Computation and Language · Computer Science 2024-04-10 Jesutofunmi A. Omiye , Haiwen Gui , Shawheen J. Rezaei , James Zou , Roxana Daneshjou

The drug development process necessitates that pharmacologists undertake various tasks, such as reviewing literature, formulating hypotheses, designing experiments, and interpreting results. Each stage requires accessing and querying vast…

Computation and Language · Computer Science 2023-08-01 Hong Lu , Chuan Li , Yinheng Li , Jie Zhao

Codification of free-text clinical narratives have long been recognised to be beneficial for secondary uses such as funding, insurance claim processing and research. The current scenario of assigning codes is a manual process which is very…

Computation and Language · Computer Science 2021-07-23 Rajvir Kaur , Jeewani Anupama Ginige , Oliver Obst

Clinical trial matching is the task of identifying trials for which patients may be potentially eligible. Typically, this task is labor-intensive and requires detailed verification of patient electronic health records (EHRs) against the…

Despite their strong linguistic capabilities, Large Language Models (LLMs) are computationally demanding and require substantial resources for fine-tuning, which is unadapted to privacy and budget constraints of many healthcare settings. To…

Computation and Language · Computer Science 2026-04-30 Pierre Epron , Adrien Coulet , Mehwish Alam

Multimodal Large Language Models (MLLMs) have shown transformative potential in medical applications, yet their performance is hindered by conventional data curation strategies that rely on coarse-grained partitioning by modality or…

Computation and Language · Computer Science 2026-04-29 Jianghang Lin , Haihua Yang , Deli Yu , Kai Wu , Kai Ye , Jinghao Lin , Zihan Wang , Yuhang Wu , Liujuan Cao

Metadata play a crucial role in ensuring the findability, accessibility, interoperability, and reusability of datasets. This paper investigates the potential of large language models (LLMs), specifically GPT-4, to improve adherence to…

Artificial Intelligence · Computer Science 2025-02-24 Sowmya S. Sundaram , Benjamin Solomon , Avani Khatri , Anisha Laumas , Purvesh Khatri , Mark A. Musen

Information extraction from textual documents such as hospital records and healthrelated user discussions has become a topic of intense interest. The task of medical concept coding is to map a variable length text to medical concepts and…

Computation and Language · Computer Science 2018-05-03 Elena Tutubalina , Zulfat Miftahutdinov

LLMs are increasingly explored for malware analysis; however, current LLM-based malware attribution remains limited by unsupported indicators and insufficient code-level grounding for identifying malicious and vulnerable code segments. To…

Cryptography and Security · Computer Science 2026-05-08 Christopher G. Pedraza Pohlenz , Hassan Jalil Hadi , Ali Hassan , Ali Shoker

International Classification of Diseases(ICD) is an authoritative health care classification system of different diseases and conditions for clinical and management purposes. Considering the complicated and dedicated process to assign…

Computation and Language · Computer Science 2022-01-13 Haoran Shi , Pengtao Xie , Zhiting Hu , Ming Zhang , Eric P. Xing

Passively collected behavioral health data from ubiquitous sensors holds significant promise to provide mental health professionals insights from patient's daily lives; however, developing analysis tools to use this data in clinical…

Analyzing vast textual data and summarizing key information from electronic health records imposes a substantial burden on how clinicians allocate their time. Although large language models (LLMs) have shown promise in natural language…

Large Language Models (LLMs) are increasingly adopted for applications in healthcare, reaching the performance of domain experts on tasks such as question answering and document summarisation. Despite their success on these tasks, it is…

Computation and Language · Computer Science 2025-05-20 Aishik Nagar , Viktor Schlegel , Thanh-Tung Nguyen , Hao Li , Yuping Wu , Kuluhan Binici , Stefan Winkler

Pre-trained Large Language Models (LLMs) often struggle on out-of-domain datasets like healthcare focused text. We explore specialized pre-training to adapt smaller LLMs to different healthcare datasets. Three methods are assessed:…

Computation and Language · Computer Science 2024-04-01 Niall Taylor , Dan Schofield , Andrey Kormilitzin , Dan W Joyce , Alejo Nevado-Holgado

It is becoming increasingly emphasis on the importance of LLM participating in clinical diagnosis decision-making. However, the low specialization refers to that current medical LLMs can not provide specific medical advice, which are more…

Computation and Language · Computer Science 2023-12-06 Binbin Li , Tianxin Meng , Xiaoming Shi , Jie Zhai , Tong Ruan

Linking (aligning) biomedical concepts across diverse data sources enables various integrative analyses, but it is challenging due to the discrepancies in concept naming conventions. Various strategies have been developed to overcome this…

Information Retrieval · Computer Science 2024-05-14 Yuzhang Xie , Jiaying Lu , Joyce Ho , Fadi Nahab , Xiao Hu , Carl Yang

The extraction of critical patient information from Electronic Health Records (EHRs) poses significant challenges due to the complexity and unstructured nature of the data. Traditional machine learning approaches often fail to capture…

Computation and Language · Computer Science 2025-09-03 Zhimeng Luo , Abhibha Gupta , Adam Frisch , Daqing He

Large language models (LLMs) have achieved strong performance on medical exam-style tasks, motivating growing interest in their deployment in real-world clinical settings. However, clinical decision-making is inherently safety-critical,…

Computation and Language · Computer Science 2026-04-13 Xiaohan Ren , Chenxiao Fan , Wenyin Ma , Hongliang He , Chongming Gao , Xiaoyan Zhao , Fuli Feng

Recent advances in large language models (LLMs) have demonstrated notable performance in medical licensing exams. However, comprehensive evaluation of LLMs across various healthcare roles, particularly in high-stakes clinical scenarios,…

Computation and Language · Computer Science 2025-06-16 Junyu Liu , Kaiqi Yan , Tianyang Wang , Qian Niu , Momoko Nagai-Tanima , Tomoki Aoyama