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To improve the performance of Intensive Care Units (ICUs), the field of bio-statistics has developed scores which try to predict the likelihood of negative outcomes. These help evaluate the effectiveness of treatments and clinical practice,…

Machine Learning · Computer Science 2019-08-23 William Caicedo-Torres , Jairo Gutierrez

The rapid progress in clinical data management systems and artificial intelligence approaches enable the era of personalized medicine. Intensive care units (ICUs) are the ideal clinical research environment for such development because they…

Computation and Language · Computer Science 2022-09-28 Thanh-Dung Le , Rita Noumeir , Jerome Rambaud , Guillaume Sans , Philippe Jouvet

Early prediction of patients at risk of clinical deterioration can help physicians intervene and alter their clinical course towards better outcomes. In addition to the accuracy requirement, early warning systems must make the predictions…

Machine Learning · Computer Science 2021-02-16 Ibrahim Hammoud , Prateek Prasanna , IV Ramakrishnan , Adam Singer , Mark Henry , Henry Thode

Background. Chronic pain afflicts 20 % of the global population. A strictly biomedical mind-set leaves many sufferers chasing somatic cures and has fuelled the opioid crisis. The biopsychosocial model recognises pain subjective,…

Neurons and Cognition · Quantitative Biology 2025-06-27 Saar Draznin Shiran , Boris Boltyansky , Alexandra Zhuravleva , Dmitry Scherbakov , Pavel Goldstein

Electronic health records (EHRs) are designed to synthesize diverse data types, including unstructured clinical notes, structured lab tests, and time-series visit data. Physicians draw on these multimodal and temporal sources of EHR data to…

Clinical text provides essential information to estimate the acuity of a patient during hospital stays in addition to structured clinical data. In this study, we explore how clinical text can complement a clinical predictive learning task.…

We present a new Hebrew medical language model designed to extract structured clinical timelines from electronic health records, enabling the construction of patient journeys. Our model is based on DictaBERT 2.0 and continually pre-trained…

The large amount of time clinicians spend sifting through patient notes and documenting in electronic health records (EHRs) is a leading cause of clinician burnout. By proactively and dynamically retrieving relevant notes during the…

Information Retrieval · Computer Science 2023-08-17 Sharon Jiang , Shannon Shen , Monica Agrawal , Barbara Lam , Nicholas Kurtzman , Steven Horng , David Karger , David Sontag

Accurately labeling biomedical data presents a challenge. Traditional semi-supervised learning methods often under-utilize available unlabeled data. To address this, we propose a novel reliability-based training data cleaning method…

Machine Learning · Computer Science 2023-09-15 Xianghao Zhan , Qinmei Xu , Yuanning Zheng , Guangming Lu , Olivier Gevaert

Intensive care units (ICU) generate long, dense and evolving streams of clinical information, where physicians must repeatedly reassess patient states under time pressure, underscoring a clear need for reliable AI decision support. Existing…

Artificial Intelligence · Computer Science 2026-05-14 Chengzhi Shen , Weixiang Shen , Tobias Susetzky , Chen , Chen , Jun Li , Yuyuan Liu , Xuepeng Zhang , Zhenyu Gong , Daniel Rueckert , Jiazhen Pan

Predicting patient mortality is an important and challenging problem in the healthcare domain, especially for intensive care unit (ICU) patients. Electronic health notes serve as a rich source for learning patient representations, that can…

Computation and Language · Computer Science 2019-10-16 Shaika Chowdhury , Chenwei Zhang , Philip S. Yu , Yuan Luo

Viewing the trajectory of a patient as a dynamical system, a recurrent neural network was developed to learn the course of patient encounters in the Pediatric Intensive Care Unit (PICU) of a major tertiary care center. Data extracted from…

Machine Learning · Statistics 2017-01-25 M Aczon , D Ledbetter , L Ho , A Gunny , A Flynn , J Williams , R Wetzel

Heart failure affects millions of people worldwide, significantly reducing quality of life and leading to high mortality rates. Despite extensive research, the relationship between heart failure and mortality rates among ICU patients is not…

Machine Learning · Computer Science 2024-09-04 Negin Ashrafi , Armin Abdollahi , Jiahong Zhang , Maryam Pishgar

Time series data are prevalent in electronic health records, mostly in the form of physiological parameters such as vital signs and lab tests. The patterns of these values may be significant indicators of patients' clinical states and there…

Machine Learning · Computer Science 2019-11-18 Kun Zhang , Yuan Xue , Gerardo Flores , Alvin Rajkomar , Claire Cui , Andrew M. Dai

Intensive Care Units (ICU) require comprehensive patient data integration for enhanced clinical outcome predictions, crucial for assessing patient conditions. Recent deep learning advances have utilized patient time series data, and fusion…

Machine Learning · Computer Science 2023-11-14 Samyak Jain , Manuel Burger , Gunnar Rätsch , Rita Kuznetsova

Diagnosis of a clinical condition is a challenging task, which often requires significant medical investigation. Previous work related to diagnostic inferencing problems mostly consider multivariate observational data (e.g. physiological…

Computation and Language · Computer Science 2017-01-05 Aaditya Prakash , Siyuan Zhao , Sadid A. Hasan , Vivek Datla , Kathy Lee , Ashequl Qadir , Joey Liu , Oladimeji Farri

Clinical information extraction, which involves structuring clinical concepts from unstructured medical text, remains a challenging problem that could benefit from the inclusion of tabular background information available in electronic…

Artificial Intelligence · Computer Science 2025-12-10 Paloma Rabaey , Stefan Heytens , Thomas Demeester

This paper presents a reproducible and process-aware pipeline for predictive monitoring of clinical pathways. The approach integrates data lifting, temporal reconstruction, event log construction, prefix-based representations, and…

Machine Learning · Computer Science 2026-05-13 Pasquale Ardimento , Mario Luca Bernardi , Marta Cimitile , Samuele Latorre

Accurate mortality prediction allows Intensive Care Units (ICUs) to adequately benchmark clinical practice and identify patients with unexpected outcomes. Traditionally, simple statistical models have been used to assess patient death risk,…

Machine Learning · Computer Science 2020-05-20 William Caicedo-Torres , Jairo Gutierrez

Advances in data collection enable the capture of rich patient-generated data: from passive sensing (e.g., wearables and smartphones) to active self-reports (e.g., cross-sectional surveys and ecological momentary assessments). Although…