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Existing deep learning models for defining pathology from clinical imaging data rely on expert annotations and lack generalization capabilities in open clinical environments. Here, we present a generalizable vision-language model for…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Hao Yang , Hong-Yu Zhou , Jiarun Liu , Weijian Huang , Cheng Li , Zhihuan Li , Yuanxu Gao , Qiegen Liu , Yong Liang , Qi Yang , Song Wu , Tao Tan , Hairong Zheng , Kang Zhang , Shanshan Wang

Causal representation learning (CRL) seeks to recover latent variables with identifiability guarantees, typically up to permutation and component-wise reparameterization under appropriate assumptions. However, identifiability does not imply…

Machine Learning · Computer Science 2026-05-08 Shicheng Fan , Nour Elhendawy , Jianle Sun , Ke Fang , Kun Zhang , Yihang Wang , Lu Cheng

Multimodal data provides heterogeneous information for a holistic understanding of the tumor microenvironment. However, existing AI models often struggle to harness the rich information within multimodal data and extract poorly…

Machine Learning · Computer Science 2025-09-17 Huajun Zhou , Fengtao Zhou , Jiabo Ma , Yingxue Xu , Xi Wang , Xiuming Zhang , Li Liang , Zhenhui Li , Hao Chen

The emergence of Large Language Models (LLMs) presents unprecedented opportunities to revolutionize medical contrastive vision-language pre-training. In this paper, we show how LLMs can facilitate large-scale supervised pre-training,…

Computer Vision and Pattern Recognition · Computer Science 2025-09-17 Yingtai Li , Haoran Lai , Xiaoqian Zhou , Shuai Ming , Wenxin Ma , Wei Wei , Shaohua Kevin Zhou

Large Language Models (LLMs) are increasingly deployed in sensitive applications including psychological support, healthcare, and high-stakes decision-making. This expansion has motivated growing research into the ethical and moral…

Computers and Society · Computer Science 2026-03-03 Erica Coppolillo , Emilio Ferrara

This study evaluates how well large language models (LLMs) can classify ICD-10 codes from hospital discharge summaries, a critical but error-prone task in healthcare. Using 1,500 summaries from the MIMIC-IV dataset and focusing on the 10…

Computation and Language · Computer Science 2025-07-08 Akram Mustafa , Usman Naseem , Mostafa Rahimi Azghadi

Large-language models have recently demonstrated impressive zero-shot capabilities in a variety of natural language tasks such as summarization, dialogue generation, and question-answering. Despite many promising applications in clinical…

This technical report presents MOSaiC 3.6.2, a web-based collaborative platform designed for the annotation and evaluation of medical videos. MOSaiC is engineered to facilitate video-based assessment and accelerate surgical data science…

Computer Vision and Pattern Recognition · Computer Science 2023-12-15 Jean-Paul Mazellier , Antoine Boujon , Méline Bour-Lang , Maël Erharhd , Julien Waechter , Emilie Wernert , Pietro Mascagni , Nicolas Padoy

An important objective in computational biology is the efficient integration of multi-omics data. The task of integration comes with challenges: multi-omics data are most often unpaired (requiring diagonal integration), partially labeled…

Machine Learning · Computer Science 2025-09-16 Daniel Lepe-Soltero , Thierry Artières , Anaïs Baudot , Paul Villoutreix

Conversational AI tools that can generate and discuss clinically correct radiology reports for a given medical image have the potential to transform radiology. Such a human-in-the-loop radiology assistant could facilitate a collaborative…

Computer Vision and Pattern Recognition · Computer Science 2025-05-08 Chantal Pellegrini , Ege Özsoy , Benjamin Busam , Nassir Navab , Matthias Keicher

This study presents DiagCoT, a multi-stage framework that applies supervised fine-tuning to general-purpose vision-language models (VLMs) to emulate radiologists' stepwise diagnostic reasoning using only free-text reports. DiagCoT combines…

Artificial Intelligence · Computer Science 2025-09-09 Yihong Luo , Wenwu He , Zhuo-Xu Cui , Dong Liang

A ubiquitous task in processing electronic medical data is the assignment of standardized codes representing diagnoses and/or procedures to free-text documents such as medical reports. This is a difficult natural language processing task…

Deep learning models have achieved remarkable accuracy in chest X-ray diagnosis, yet their widespread clinical adoption remains limited by the black-box nature of their predictions. Clinicians require transparent, verifiable explanations to…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Yiming Tang , Wenjia Zhong , Rushi Shah , Dianbo Liu

In recent years, accurately and quickly deploying medical large language models (LLMs) has become a trend. Among these, retrieval-augmented generation (RAG) has garnered attention due to rapid deployment and privacy protection. However, the…

Computation and Language · Computer Science 2025-08-06 Penglei Sun , Yixiang Chen , Xiang Li , Xiaowen Chu

Automated radiology report generation (RRG) aims to produce detailed textual reports from clinical imaging, such as computed tomography (CT) scans, to improve the accuracy and efficiency of diagnosis and provision of management advice. RRG…

Machine Learning · Computer Science 2025-07-03 Siyou Li , Pengyao Qin , Huanan Wu , Dong Nie , Arun J. Thirunavukarasu , Juntao Yu , Le Zhang

We present a cost-effective method to integrate speech into a large language model (LLM), resulting in a Contextual Speech Model with Instruction-following/in-context-learning Capabilities (COSMIC) multi-modal LLM. Using GPT-3.5, we…

Computation and Language · Computer Science 2024-06-17 Jing Pan , Jian Wu , Yashesh Gaur , Sunit Sivasankaran , Zhuo Chen , Shujie Liu , Jinyu Li

The integration of medical images with clinical context is essential for generating accurate and clinically interpretable radiology reports. However, current automated methods often rely on resource-heavy Large Language Models (LLMs) or…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Nagur Shareef Shaik , Teja Krishna Cherukuri , Adnan Masood , Dong Hye Ye

While Large Language Models (LLMs) are emerging as a promising direction in computational pathology, the substantial computational cost of giga-pixel Whole Slide Images (WSIs) necessitates the use of Multi-Instance Learning (MIL) to enable…

Computer Vision and Pattern Recognition · Computer Science 2025-11-12 Zhenfeng Zhuang , Fangyu Zhou , Liansheng Wang

Purpose: We investigated the utilization of privacy-preserving, locally-deployed, open-source Large Language Models (LLMs) to extract diagnostic information from free-text cardiovascular magnetic resonance (CMR) reports. Materials and…

Computers and Society · Computer Science 2025-06-03 Sina Amirrajab , Volker Vehof , Michael Bietenbeck , Ali Yilmaz

Medical report generation from imaging data remains a challenging task in clinical practice. While large language models (LLMs) show great promise in addressing this challenge, their effective integration with medical imaging data still…

Computer Vision and Pattern Recognition · Computer Science 2025-06-19 Chunlei Li , Jingyang Hou , Yilei Shi , Jingliang Hu , Xiao Xiang Zhu , Lichao Mou