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This study examines the effect of prompt engineering on the performance of Large Language Models (LLMs) in clinical note generation. We introduce an Automatic Prompt Optimization (APO) framework to refine initial prompts and compare the…

Computation and Language · Computer Science 2024-07-08 Zonghai Yao , Ahmed Jaafar , Beining Wang , Zhichao Yang , Hong Yu

Traditional Korean medicine (TKM) emphasizes individualized diagnosis and treatment. This uniqueness makes AI modeling difficult due to limited data and implicit processes. Large language models (LLMs) have demonstrated impressive medical…

Computation and Language · Computer Science 2023-12-19 Dongyeop Jang , Tae-Rim Yun , Choong-Yeol Lee , Young-Kyu Kwon , Chang-Eop Kim

A medical provider's summary of a patient visit serves several critical purposes, including clinical decision-making, facilitating hand-offs between providers, and as a reference for the patient. An effective summary is required to be…

Computation and Language · Computer Science 2023-05-11 Varun Nair , Elliot Schumacher , Anitha Kannan

This work evaluates FinGPT, a financial domain-specific language model, across six key natural language processing (NLP) tasks: Sentiment Analysis, Text Classification, Named Entity Recognition, Financial Question Answering, Text…

Computation and Language · Computer Science 2025-07-14 Prudence Djagba , Chimezie A. Odinakachukwu

The availability of biomedical text data and advances in natural language processing (NLP) have made new applications in biomedical NLP possible. Language models trained or fine tuned using domain specific corpora can outperform general…

Computation and Language · Computer Science 2021-07-12 Usman Naseem , Adam G. Dunn , Matloob Khushi , Jinman Kim

Large language models (LLMs) have shown great potential in medical question answering (MedQA), yet adapting them to biomedical reasoning remains challenging due to domain-specific complexity and limited supervision. In this work, we study…

Computation and Language · Computer Science 2025-11-12 Chenqian Le , Ziheng Gong , Chihang Wang , Haowei Ni , Panfeng Li , Xupeng Chen

Materials language processing (MLP) is one of the key facilitators of materials science research, as it enables the extraction of structured information from massive materials science literature. Prior works suggested high-performance MLP…

Computation and Language · Computer Science 2023-08-21 Jaewoong Choi , Byungju Lee

Generative pre-trained transformer (GPT) models have shown promise in clinical entity and relation extraction tasks because of their precise extraction and contextual understanding capability. In this work, we further leverage the Unified…

Computation and Language · Computer Science 2024-07-16 Kriti Bhattarai , Inez Y. Oh , Zachary B. Abrams , Albert M. Lai

Objective: Clinical trials are essential for advancing pharmaceutical interventions, but they face a bottleneck in selecting eligible participants. Although leveraging electronic health records (EHR) for recruitment has gained popularity,…

Computation and Language · Computer Science 2026-01-15 Mojdeh Rahmanian , Seyed Mostafa Fakhrahmad , Seyedeh Zahra Mousavi

For years, semantic interoperability standards have sought to streamline the exchange of clinical data, yet their deployment remains time-consuming, resource-intensive, and technically challenging. To address this, we introduce a…

Computation and Language · Computer Science 2025-07-08 Alvaro Riquelme , Pedro Costa , Catalina Martinez

ChatGPT explores a strategic blueprint of question answering (QA) in delivering medical diagnosis, treatment recommendations, and other healthcare support. This is achieved through the increasing incorporation of medical domain data via…

Computation and Language · Computer Science 2024-01-23 Qing Li , Lei Li , Yu Li

In the rapidly evolving field of natural language processing, the translation of linguistic descriptions into mathematical formulation of optimization problems presents a formidable challenge, demanding intricate understanding and…

Computation and Language · Computer Science 2024-03-05 Tasnim Ahmed , Salimur Choudhury

As ChatGPT and GPT-4 spearhead the development of Large Language Models (LLMs), more researchers are investigating their performance across various tasks. But more research needs to be done on the interpretability capabilities of LLMs, that…

Computation and Language · Computer Science 2023-10-27 Dongfang Li , Jindi Yu , Baotian Hu , Zhenran Xu , Min Zhang

Understanding how individuals with Parkinson's disease (PD) describe cognitive experiences in their daily lives can offer valuable insights into disease-related cognitive and emotional changes. However, extracting such information from…

Computation and Language · Computer Science 2025-11-13 Varada Khanna , Nilay Bhatt , Ikgyu Shin , Sule Tinaz , Yang Ren , Hua Xu , Vipina K. Keloth

The strong few-shot in-context learning capability of large pre-trained language models (PLMs) such as GPT-3 is highly appealing for application domains such as biomedicine, which feature high and diverse demands of language technologies…

Computation and Language · Computer Science 2022-11-08 Bernal Jiménez Gutiérrez , Nikolas McNeal , Clay Washington , You Chen , Lang Li , Huan Sun , Yu Su

The clinical adoption of biomedical vision-language models is hindered by prompt optimization techniques that produce either uninterpretable latent vectors or single textual prompts. This lack of transparency and failure to capture the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-20 Kaushitha Silva , Mansitha Eashwara , Sanduni Ubayasiri , Ruwan Tennakoon , Damayanthi Herath

In the past decade a surge in the amount of electronic health record (EHR) data in the United States, attributed to a favorable policy environment created by the Health Information Technology for Economic and Clinical Health (HITECH) Act of…

Computation and Language · Computer Science 2025-12-08 Ivan Makohon , Mohamad Najafi , Jian Wu , Mathias Brochhausen , Yaohang Li

Automated knowledge curation for biomedical ontologies is key to ensure that they remain comprehensive, high-quality and up-to-date. In the era of foundational language models, this study compares and analyzes three NLP paradigms for…

Machine Learning · Computer Science 2023-12-21 Emily Groves , Minhong Wang , Yusuf Abdulle , Holger Kunz , Jason Hoelscher-Obermaier , Ronin Wu , Honghan Wu

Large Language Models (LLMs) demonstrate remarkable versatility in various NLP tasks but encounter distinct challenges in biomedical due to the complexities of language and data scarcity. This paper investigates LLMs application in the…

Computation and Language · Computer Science 2024-07-12 Masoud Monajatipoor , Jiaxin Yang , Joel Stremmel , Melika Emami , Fazlolah Mohaghegh , Mozhdeh Rouhsedaghat , Kai-Wei Chang

Large language models (LLMs) can simulate clinical reasoning based on natural language prompts, but their utility in ophthalmology is largely unexplored. This study evaluated GPT-4's ability to interpret structured textual descriptions of…

Computation and Language · Computer Science 2025-07-03 Cindy Lie Tabuse , David Restepo , Carolina Gracitelli , Fernando Korn Malerbi , Caio Regatieri , Luis Filipe Nakayama