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Due to their chemical and structural diversity, nanoporous materials can be used in a wide variety of applications, including fluid separation, gas storage, heterogeneous catalysis, drug delivery, etc. Given the large and rapidly increasing…

Materials Science · Physics 2022-06-20 Emmanuel Ren , Philippe Guilbaud , François-Xavier Coudert

There is an ongoing debate on personalization, adapting results to the unique user exploiting a user's personal history, versus customization, adapting results to a group profile sharing one or more characteristics with the user at hand.…

Information Retrieval · Computer Science 2016-09-05 Mostafa Dehghani , Hosein Azarbonyad , Jaap Kamps , Maarten Marx

We introduce a combinatorial optimization-enriched machine learning pipeline and a novel learning paradigm to solve inventory routing problems with stochastic demand and dynamic inventory updates. After each inventory update, our approach…

Optimization and Control · Mathematics 2024-02-08 Toni Greif , Louis Bouvier , Christoph M. Flath , Axel Parmentier , Sonja U. K. Rohmer , Thibaut Vidal

We propose a major revision of the format XCSP 2.1, called XCSP3, to build integrated representations of combinatorial constrained problems. This new format is able to deal with mono/multi optimization, many types of variables, cost…

Artificial Intelligence · Computer Science 2024-08-30 Frederic Boussemart , Christophe Lecoutre , Gilles Audemard , Cédric Piette

Long reads produced by third-generation sequencing technologies are used to construct an assembly (i.e., the subject's genome), which is further used in downstream genome analysis. Unfortunately, long reads have high sequencing error rates…

Genomics · Quantitative Biology 2020-10-29 Can Firtina , Jeremie S. Kim , Mohammed Alser , Damla Senol Cali , A. Ercument Cicek , Can Alkan , Onur Mutlu

We present Ecole, a new library to simplify machine learning research for combinatorial optimization. Ecole exposes several key decision tasks arising in general-purpose combinatorial optimization solvers as control problems over Markov…

Machine Learning · Computer Science 2020-11-26 Antoine Prouvost , Justin Dumouchelle , Lara Scavuzzo , Maxime Gasse , Didier Chételat , Andrea Lodi

Choosing an optimal strategy for hierarchical group testing is an important problem for practitioners who are interested in disease screening with limited resources. For example, when screening for infectious diseases in large populations,…

Methodology · Statistics 2020-02-27 Yaakov Malinovsky , Gregory Haber , Paul S. Albert

Peer reviews, evaluations, and selections are a fundamental aspect of modern science. Funding bodies the world over employ experts to review and select the best proposals from those submitted for funding. The problem of peer selection,…

Computer Science and Game Theory · Computer Science 2019-05-01 Haris Aziz , Omer Lev , Nicholas Mattei , Jeffrey S. Rosenschein , Toby Walsh

Agile software teams are expected to follow a number of specific Team Practices (TPs) during each iteration, such as estimating the effort ("points") required to complete user stories and coordinating the management of the codebase with the…

Software Engineering · Computer Science 2021-03-12 Cesar Garcia , Alejandro Guerrero , Joshua Zeitsoff , Srujay Korlakunta , Pablo Fernandez , Armando Fox , Antonio Ruiz-Cortes

For large libraries of small molecules, exhaustive combinatorial chemical screens become infeasible to perform when considering a range of disease models, assay conditions, and dose ranges. Deep learning models have achieved state of the…

In recent years, much of the research on clustering algorithms has primarily focused on enhancing their accuracy and efficiency, frequently at the expense of interpretability. However, as these methods are increasingly being applied in…

Machine Learning · Computer Science 2026-01-21 Lianyu Hu , Mudi Jiang , Junjie Dong , Xinying Liu , Zengyou He

In this paper, we present pomdp_py, a general purpose Partially Observable Markov Decision Process (POMDP) library written in Python and Cython. Existing POMDP libraries often hinder accessibility and efficient prototyping due to the…

Artificial Intelligence · Computer Science 2020-04-22 Kaiyu Zheng , Stefanie Tellex

Molecular docking is a key task in computational biology that has attracted increasing interest from the machine learning community. While existing methods have achieved success, they generally treat each protein-ligand pair in isolation.…

Biomolecules · Quantitative Biology 2025-01-28 Jiaqi Guan , Jiahan Li , Xiangxin Zhou , Xingang Peng , Sheng Wang , Yunan Luo , Jian Peng , Jianzhu Ma

The current bulk materials discovery cycle has several inefficiencies from initial computational predictions through fabrication and analyses. Materials are generally evaluated in a singular fashion, relying largely on human-driven…

Materials Science · Physics 2021-02-12 Olivia F. Dippo , Kevin R. Kaufmann , Kenneth S. Vecchio

Concolic testing is a popular dynamic validation technique that can be used for both model checking and automatic test case generation. We have recently introduced concolic testing in the context of logic programming. In contrast to…

Logic in Computer Science · Computer Science 2016-08-11 Fred Mesnard , Etienne Payet , German Vidal

Information-theoretic quantities like entropy and mutual information have found numerous uses in machine learning. It is well known that there is a strong connection between these entropic quantities and submodularity since entropy over a…

Machine Learning · Computer Science 2021-03-04 Rishabh Iyer , Ninad Khargonkar , Jeff Bilmes , Himanshu Asnani

Combinatorial optimization augmented machine learning (COAML) has recently emerged as a powerful paradigm for integrating predictive models with combinatorial decision-making. By embedding combinatorial optimization oracles into learning…

Machine Learning · Computer Science 2026-01-16 Maximilian Schiffer , Heiko Hoppe , Yue Su , Louis Bouvier , Axel Parmentier

Disordered proteins play essential roles in myriad cellular processes, yet their structural characterization remains a major challenge due to their dynamic and heterogeneous nature. We here present a community-driven initiative to address…

We propose the QHyper library, which is aimed at researchers working on computational experiments with a variety of quantum combinatorial optimization solvers. The library offers a simple and extensible interface for formulating…

Mathematical Software · Computer Science 2024-09-25 Tomasz Lamża , Justyna Zawalska , Kacper Jurek , Mariusz Sterzel , Katarzyna Rycerz

Determining the physicochemical properties of a protein can reveal important insights in their structure, biological functions, stability, and interactions with other molecules. Although tools for computing properties of proteins already…

Biomolecules · Quantitative Biology 2023-12-05 Gustavo Sganzerla Martinez , Mansi Dutt , Anuj Kumar , David J Kelvin