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Life occurs in concentrated `Ringer Solutions' derived from seawater that Lesser Blum studied for most of his life. As we worked together, Lesser and I realized that the questions asked of those solutions were quite different in biology…

Other Quantitative Biology · Quantitative Biology 2021-09-24 Bob Eisenberg

Soft and active condensed matter represent a class of fascinating materials that we encounter in our everyday lives -- and constitute life itself. Control signals interact with the dynamics of these systems, and this influence is formalized…

Soft Condensed Matter · Physics 2025-04-14 José Alvarado , Erin Teich , David Sivak , John Bechhoefer

The current science of cities can provide a useful foundation for future urban policies, provided that these proposals have been validated by correct observations of the diversity of situations in the world. However, international…

Physics and Society · Physics 2020-05-21 Juste Raimbault , Eric Denis , Denise Pumain

Active sensing is traditionally defined as the expenditure of energy, typically in the form of movement, for obtaining information. Here, we propose that the combination of reliance on adaptive sensors, the linkage between movement and…

Neurons and Cognition · Quantitative Biology 2026-05-25 Andrew Lamperski , Debojyoti Biswas , Eric S. Fortune , John Guckenheimer , Kathleen Hoffman , Noah J. Cowan

Mathematical and computational models can assist in gaining an understanding of cell behavior at many levels of organization. Here, we review models in the literature that focus on eukaryotic cell motility at 3 size scales: intracellular…

Cell Behavior · Quantitative Biology 2021-01-27 Andreas Buttenschön , Leah Edelstein-Keshet

Many biological phenomena such as locomotion, circadian cycles, and breathing are rhythmic in nature and can be modeled as rhythmic dynamical systems. Dynamical systems modeling often involves neglecting certain characteristics of a…

Dynamical Systems · Mathematics 2016-01-20 M. Mert Ankaralı , Shahin Sefati , Manu S. Madhav , Andrew Long , Amy J. Bastian , Noah J. Cowan

In this Chapter, we ask questions (1) What is the right way to measure the quality of information processing in a biological system? and (2) What can real-life organisms do in order to improve their performance in information-processing…

Quantitative Methods · Quantitative Biology 2010-11-25 Ilya Nemenman

One of the central aims of neuroscience is to reliably predict the behavioral response of an organism using its neural activity. If possible, this implies we can causally manipulate the neural response and design brain-computer-interface…

Neurons and Cognition · Quantitative Biology 2025-04-01 Jayanth R Taranath

Efficient energy transduction is one driver of evolution; and thus understanding biomolecular energy transduction is crucial to understanding living organisms. As an energy-orientated modelling methodology, bond graphs provide a useful…

Molecular Networks · Quantitative Biology 2018-06-11 Peter J. Gawthrop , Edmund J. Crampin

Plants solve complex problems without centralized control, relying instead on growth-driven dynamics to sense, navigate, and optimize resource acquisition. This review presents a unified physical framework for understanding plant behavior…

Other Condensed Matter · Physics 2026-04-24 Yasmine Meroz

One of the basic frameworks in science views behavioral products as a process within a dynamic system. The mechanism might be seen as a representation of many instances of centralized control in real time. Many real systems, however,…

Dynamical Systems · Mathematics 2019-08-19 Chulwook Park

Statistical mechanics is one of the most powerful and elegant tools in the quantitative sciences. One key virtue of statistical mechanics is that it is designed to examine large systems with many interacting degrees of freedom, providing a…

Quantitative Methods · Quantitative Biology 2007-08-15 Hernan G. Garcia , Jané Kondev , Nigel Orme , Julie A. Theriot , Rob Phillips

Statistical mechanics provides a useful analog for understanding the behavior of complex adaptive systems, including power markets and the power systems they intend to govern. Transaction-based control is founded on the conjecture that the…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 David P. Chassin

The need for high-throughput, precise, and meaningful methods for measuring behavior has been amplified by our recent successes in measuring and manipulating neural circuitry. The largest challenges associated with moving in this direction,…

Biological Physics · Physics 2017-12-18 Gordon J. Berman

Evolution has fascinated quantitative and physical scientists for decades: how can the random process of mutation, recombination, and duplication of genetic information generate the diversity of life? What determines the rate of evolution?…

Populations and Evolution · Quantitative Biology 2018-04-23 Richard A. Neher , Aleksandra M. Walczak

Many biological regulatory systems process signals out of steady state and respond with a physiological delay. A simple model of regulation which respects these features shows how the ability of a delayed output to transmit information is…

Molecular Networks · Quantitative Biology 2013-08-13 Francesca Mancini , Chris H. Wiggins , Matteo Marsili , Aleksandra M. Walczak

This paper is a preliminary work to address the problem of dynamical systems with parameters varying in time. An idea to predict their behaviour is proposed. These systems are called \emph{transient systems}, and are distinguished from…

Dynamical Systems · Mathematics 2014-11-04 Ugo Galvanetto , Luca Magri

Biological and robotic grasp and manipulation are undeniably similar at the level of mechanical task performance. However, their underlying fundamental biological vs. engineering mechanisms are, by definition, dramatically different and can…

Robotics · Computer Science 2017-10-25 Francisco J Valero-Cuevas , Marco Santello

Cognitive control is a suite of processes that helps individuals pursue goals despite resistance or uncertainty about what to do. Although cognitive control has been extensively studied as a dynamic feedback loop of perception, valuation,…

Active biological flow networks pervade nature and span a wide range of scales, from arterial blood vessels and bronchial mucus transport in humans to bacterial flow through porous media or plasmodial shuttle streaming in slime molds.…

Biological Physics · Physics 2016-07-28 Francis G. Woodhouse , Aden Forrow , Joanna B. Fawcett , Jörn Dunkel
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