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After the tremendous advances of deep learning and other AI methods, more attention is flowing into other properties of modern approaches, such as interpretability, fairness, etc. combined in frameworks like Responsible AI. Two research…

Artificial Intelligence · Computer Science 2021-05-26 Dominik Seuß

AI predictive systems are increasingly embedded in decision making pipelines, shaping high stakes choices once made solely by humans. Yet robust decisions under uncertainty still rely on capabilities that current AI lacks: domain knowledge…

Artificial Intelligence · Computer Science 2025-10-28 Sima Noorani , Shayan Kiyani , George Pappas , Hamed Hassani

This study investigates uncertainty quantification in large language models (LLMs) for medical applications, emphasizing both technical innovations and philosophical implications. As LLMs become integral to clinical decision-making,…

Artificial Intelligence · Computer Science 2025-04-08 Zahra Atf , Seyed Amir Ahmad Safavi-Naini , Peter R. Lewis , Aref Mahjoubfar , Nariman Naderi , Thomas R. Savage , Ali Soroush

This paper addresses the unique challenges associated with uncertainty quantification in AI models when applied to patient-facing contexts within healthcare. Unlike traditional eXplainable Artificial Intelligence (XAI) methods tailored for…

Artificial Intelligence · Computer Science 2024-08-06 Adarsa Sivaprasad , Ehud Reiter

Reliable uncertainty quantification is a first step towards building explainable, transparent, and accountable artificial intelligent systems. Recent progress in Bayesian deep learning has made such quantification realizable. In this paper,…

Computation and Language · Computer Science 2018-11-20 Yijun Xiao , William Yang Wang

Uncertainty quantification (UQ) is a critical aspect of artificial intelligence (AI) systems, particularly in high-risk domains such as healthcare, autonomous systems, and financial technology, where decision-making processes must account…

Artificial intelligence (AI) systems accelerate medical workflows and improve diagnostic accuracy in healthcare, serving as second-opinion systems. However, the unpredictability of AI errors poses a significant challenge, particularly in…

AI has been dealing with uncertainty to have highly accurate results. This becomes even worse with reasonably small data sets or a variation in the data sets. This has far-reaching effects on decision-making, forecasting and learning…

Artificial Intelligence · Computer Science 2024-08-05 Keivan Shariatmadar

The last decade in deep learning has brought on increasingly capable systems that are deployed on a wide variety of applications. In natural language processing, the field has been transformed by a number of breakthroughs including large…

Artificial Intelligence · Computer Science 2024-10-23 Dennis Ulmer

The rapid growth and diversity in service offerings and the ensuing complexity of information technology ecosystems present numerous management challenges (both operational and strategic). Instrumentation and measurement technology is, by…

Software Engineering · Computer Science 2012-06-26 Moises Goldszmidt

Large-language models (LLMs) and chatbot agents are known to provide wrong outputs at times, and it was recently found that this can never be fully prevented. Hence, uncertainty quantification plays a crucial role, aiming to quantify the…

Machine Learning · Computer Science 2025-05-29 Michael Kirchhof , Gjergji Kasneci , Enkelejda Kasneci

AI Uncertainty Quantification (UQ) has the potential to improve human decision-making beyond AI predictions alone by providing additional probabilistic information to users. The majority of past research on AI and human decision-making has…

Artificial Intelligence · Computer Science 2024-02-07 Laura R. Marusich , Jonathan Z. Bakdash , Yan Zhou , Murat Kantarcioglu

AI and ML models have already found many applications in critical domains, such as healthcare and criminal justice. However, fully automating such high-stakes applications can raise ethical or fairness concerns. Instead, in such cases,…

Artificial Intelligence · Computer Science 2023-04-28 Ioannis Papantonis , Vaishak Belle

Despite AI's impressive achievements, including recent advances in generative and large language models, there remains a significant gap in the ability of AI systems to handle uncertainty and generalize beyond their training data. AI models…

Artificial Intelligence · Computer Science 2025-06-30 Shireen Kudukkil Manchingal , Andrew Bradley , Julian F. P. Kooij , Keivan Shariatmadar , Neil Yorke-Smith , Fabio Cuzzolin

Artificial Intelligence (AI) has become an integral part of domains such as security, finance, healthcare, medicine, and criminal justice. Explaining the decisions of AI systems in human terms is a key challenge--due to the high complexity…

Artificial Intelligence · Computer Science 2019-11-25 Sheikh Rabiul Islam , William Eberle , Sheikh K. Ghafoor

_Uncertainty expressions_ such as "probably" or "highly unlikely" are pervasive in human language. While prior work has established that there is population-level agreement in terms of how humans quantitatively interpret these expressions,…

Computation and Language · Computer Science 2024-11-08 Catarina G Belem , Markelle Kelly , Mark Steyvers , Sameer Singh , Padhraic Smyth

While Large Language Models (LLMs) show remarkable capabilities, their unreliability remains a critical barrier to deployment in high-stakes domains. This survey charts a functional evolution in addressing this challenge: the evolution of…

Artificial Intelligence · Computer Science 2026-04-21 Jiaxin Zhang , Wendi Cui , Zhuohang Li , Lifu Huang , Bradley Malin , Caiming Xiong , Chien-Sheng Wu

Estimating uncertainty is at the core of performing scientific measurements in HEP: a measurement is not useful without an estimate of its uncertainty. The goal of uncertainty quantification (UQ) is inextricably linked to the question, "how…

High Energy Physics - Experiment · Physics 2022-11-02 Thomas Y. Chen , Biprateep Dey , Aishik Ghosh , Michael Kagan , Brian Nord , Nesar Ramachandra

Artificial Intelligence (AI) holds the potential to dramatically improve patient care. However, it is not infallible, necessitating human-AI-collaboration to ensure safe implementation. One aspect of AI safety is the models' ability to…

Computer Vision and Pattern Recognition · Computer Science 2025-08-27 Anna M. Wundram , Christian F. Baumgartner

In safety-critical applications, language models should be able to characterize their uncertainty with meaningful probabilities. Many uncertainty quantification approaches require supervised data; however, finding suitable unseen…

Computation and Language · Computer Science 2026-05-14 Sophia Hager , Simon Zeng , Nicholas Andrews
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