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Automated methods for breast cancer detection have focused on 2D mammography and have largely ignored 3D digital breast tomosynthesis (DBT), which is frequently used in clinical practice. The two key challenges in developing automated…

Computer Vision and Pattern Recognition · Computer Science 2020-02-28 Yu Zhang , Xiaoqin Wang , Hunter Blanton , Gongbo Liang , Xin Xing , Nathan Jacobs

This work introduces a new latent diffusion model to generate high-quality 3D chest CT scans conditioned on 3D anatomical masks. The method synthesizes volumetric images of size 256x256x256 at 1 mm isotropic resolution using a single…

Computer Vision and Pattern Recognition · Computer Science 2025-10-22 Anna Oliveras , Roger Marí , Rafael Redondo , Oriol Guardià , Ana Tost , Bhalaji Nagarajan , Carolina Migliorelli , Vicent Ribas , Petia Radeva

Medical imaging analysis faces challenges such as data scarcity, high annotation costs, and privacy concerns. This paper introduces the Medical AI for Synthetic Imaging (MAISI), an innovative approach using the diffusion model to generate…

Image and Video Processing · Electrical Eng. & Systems 2025-12-16 Pengfei Guo , Can Zhao , Dong Yang , Ziyue Xu , Vishwesh Nath , Yucheng Tang , Benjamin Simon , Mason Belue , Stephanie Harmon , Baris Turkbey , Daguang Xu

Denoising diffusion models have recently achieved state-of-the-art performance in many image-generation tasks. They do, however, require a large amount of computational resources. This limits their application to medical tasks, where we…

Computer Vision and Pattern Recognition · Computer Science 2024-09-13 Florentin Bieder , Julia Wolleb , Alicia Durrer , Robin Sandkühler , Philippe C. Cattin

Breast MRI provides high-resolution volumetric imaging critical for tumor assessment and treatment planning, yet manual interpretation of 3D scans remains labor-intensive and subjective. While AI-powered tools hold promise for accelerating…

Computer Vision and Pattern Recognition · Computer Science 2025-08-01 Solha Kang , Eugene Kim , Joris Vankerschaver , Utku Ozbulak

Due to the three-dimensional nature of CT- or MR-scans, generative modeling of medical images is a particularly challenging task. Existing approaches mostly apply patch-wise, slice-wise, or cascaded generation techniques to fit the…

Image and Video Processing · Electrical Eng. & Systems 2024-10-15 Paul Friedrich , Julia Wolleb , Florentin Bieder , Alicia Durrer , Philippe C. Cattin

We propose a cascaded 3D diffusion model framework to synthesize high-fidelity 3D PET/CT volumes directly from demographic variables, addressing the growing need for realistic digital twins in oncologic imaging, virtual trials, and…

Image and Video Processing · Electrical Eng. & Systems 2025-05-29 Siyeop Yoon , Sifan Song , Pengfei Jin , Matthew Tivnan , Yujin Oh , Sekeun Kim , Dufan Wu , Xiang Li , Quanzheng Li

Magnetic Resonance Imaging (MRI) is a crucial diagnostic tool, but high-resolution scans are often slow and expensive due to extensive data acquisition requirements. Traditional MRI reconstruction methods aim to expedite this process by…

Image and Video Processing · Electrical Eng. & Systems 2025-11-11 Emmanuelle Bourigault , Abdullah Hamdi , Amir Jamaludin

Deep neural networks have brought remarkable breakthroughs in medical image analysis. However, due to their data-hungry nature, the modest dataset sizes in medical imaging projects might be hindering their full potential. Generating…

Accurate brain tumor segmentation is crucial for neuro-oncology diagnosis and treatment planning. Deep learning methods have made significant progress, but automatic segmentation still faces challenges, including tumor morphological…

Image and Video Processing · Electrical Eng. & Systems 2025-10-21 Mingda Zhang

Breast cancer is one of the most serious disease affecting women's health. Due to low cost, portable, no radiation, and high efficiency, breast ultrasound (BUS) imaging is the most popular approach for diagnosing early breast cancer.…

Computer Vision and Pattern Recognition · Computer Science 2019-10-24 Kuan Huang , Yingtao Zhang , H. D. Cheng , Ping Xing , Boyu Zhang

The clinical management of breast cancer depends on an accurate understanding of the tumor and its anatomical context to adjacent tissues and landmark structures. This context may be provided by semantic segmentation methods; however,…

Image and Video Processing · Electrical Eng. & Systems 2023-11-29 Arda Pekis , Vignesh Kannan , Evandros Kaklamanos , Anu Antony , Snehal Patel , Tyler Earnest

Medical image analysis using deep neural networks has been actively studied. Deep neural networks are trained by learning data. For accurate training of deep neural networks, the learning data should be sufficient, of good quality, and…

Image and Video Processing · Electrical Eng. & Systems 2021-01-05 Sunho Kim , Byungjai Kim , HyunWook Park

Deep learning and generative models are advancing rapidly, with synthetic data increasingly being integrated into training pipelines for downstream analysis tasks. However, in medical imaging, their adoption remains constrained by the…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Kyeonghun Kim , Jaehyeok Bae , Youngung Han , Joo Young Bae , Seoyoung Ju , Junsu Lim , Gyeongmin Kim , Nam-Joon Kim , Woo Kyoung Jeong , Ken Ying-Kai Liao , Won Jae Lee , Pa Hong , Hyuk-Jae Lee

Existing segmentation models trained on a single medical imaging dataset often lack robustness when encountering unseen organs or tumors. Developing a robust model capable of identifying rare or novel tumor categories not present during…

Computer Vision and Pattern Recognition · Computer Science 2025-07-02 Rong Wu , Ziqi Chen , Liming Zhong , Heng Li , Hai Shu

Transformer, which can benefit from global (long-range) information modeling using self-attention mechanisms, has been successful in natural language processing and 2D image classification recently. However, both local and global features…

Computer Vision and Pattern Recognition · Computer Science 2021-06-29 Wenxuan Wang , Chen Chen , Meng Ding , Jiangyun Li , Hong Yu , Sen Zha

Modern biomedical image analysis using deep learning often encounters the challenge of limited annotated data. To overcome this issue, deep generative models can be employed to synthesize realistic biomedical images. In this regard, we…

Image and Video Processing · Electrical Eng. & Systems 2026-02-23 Yuli Wu , Weidong He , Dennis Eschweiler , Ningxin Dou , Zixin Fan , Shengli Mi , Peter Walter , Johannes Stegmaier

Digital breast tomosynthesis (DBT) is an emerging modality for breast imaging. A typical tomosynthesis image is reconstructed from projection data acquired at a limited number of views over a limited angular range. In general, the…

Medical Physics · Physics 2009-08-19 I. Reiser , J. Bian , R. M. Nishikawa , E. Y. Sidky , X. Pan

Multimodal learning has been demonstrated to enhance performance across various clinical tasks, owing to the diverse perspectives offered by different modalities of data. However, existing multimodal segmentation methods rely on…

Image and Video Processing · Electrical Eng. & Systems 2026-02-04 Shiyun Chen , Li Lin , Pujin Cheng , ZhiCheng Jin , JianJian Chen , HaiDong Zhu , Kenneth K. Y. Wong , Xiaoying Tang

Diffusion models have become a leading approach for high-fidelity medical image synthesis. However, most existing methods for 3D medical image generation rely on convolutional U-Net backbones within latent diffusion frameworks. While…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Marvin Seyfarth , Salman Ul Hassan Dar , Yannik Frisch , Philipp Wild , Norbert Frey , Florian André , Sandy Engelhardt