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Low-dose computed tomography (LDCT) has become the technology of choice for diagnostic medical imaging, given its lower radiation dose compared to standard CT, despite increasing image noise and potentially affecting diagnostic accuracy. To…

Computer Vision and Pattern Recognition · Computer Science 2024-04-30 Bin Wang , Fei Deng , Peifan Jiang , Shuang Wang , Xiao Han , Zhixuan Zhang

With the development of deep learning, medical image processing has been widely used to assist clinical research. This paper focuses on the denoising problem of low-dose computed tomography using deep learning. Although low-dose computed…

Image and Video Processing · Electrical Eng. & Systems 2026-05-19 Zhilin Guan , Wei Zhang

Computed tomography (CT) is routinely used for three-dimensional non-invasive imaging. Numerous data-driven image denoising algorithms were proposed to restore image quality in low-dose acquisitions. However, considerably less research…

Image denoising is a prerequisite for downstream tasks in many fields. Low-dose and photon-counting computed tomography (CT) denoising can optimize diagnostic performance at minimized radiation dose. Supervised deep denoising methods are…

Machine Learning · Computer Science 2022-01-06 Chuang Niu , Mengzhou Li , Fenglei Fan , Weiwen Wu , Xiaodong Guo , Qing Lyu , Ge Wang

Reducing radiation doses benefits patients, however, the resultant low-dose computed tomography (LDCT) images often suffer from clinically unacceptable noise and artifacts. While deep learning (DL) shows promise in LDCT reconstruction, it…

Image and Video Processing · Electrical Eng. & Systems 2025-03-04 Ziyuan Yang , Yingyu Chen , Zhiwen Wang , Hongming Shan , Yang Chen , Yi Zhang

Digital breast tomosynthesis (DBT) exams should utilize the lowest possible radiation dose while maintaining sufficiently good image quality for accurate medical diagnosis. In this work, we propose a convolution neural network (CNN) to…

Image and Video Processing · Electrical Eng. & Systems 2022-03-23 Rodrigo de Barros Vimieiro , Chuang Niu , Hongming Shan , Lucas Rodrigues Borges , Ge Wang , Marcelo Andrade da Costa Vieira

In order to reduce the potential radiation risk, low-dose CT has attracted more and more attention. However, simply lowering the radiation dose will significantly degrade the imaging quality. In this paper, we propose a noise reduction…

Medical Physics · Physics 2016-09-28 Hu Chen , Yi Zhang , Weihua Zhang , Peixi Liao , Ke Li , Jiliu Zhou , Ge Wang

PET is affected by statistical noise due to constraints on tracer dose and scan duration, impacting both diagnostic performance and quantitative accuracy. While deep learning (DL)-based PET denoising methods have been used to improve image…

Utilizing a low-dose CT approach significantly reduces the radiation exposure for patients, yet it introduces challenges, such as increased noise and artifacts in the resultant images, which can hinder accurate medical diagnostics.…

Image and Video Processing · Electrical Eng. & Systems 2024-04-03 Helena Shawn , Thompson Chyrikov , Jacob Lanet , Lam-chi Chen , Jim Zhao , Christina Chajo

The remarkable success of deep learning methods in solving computer vision problems, such as image classification, object detection, scene understanding, image segmentation, etc., has paved the way for their application in biomedical…

Image and Video Processing · Electrical Eng. & Systems 2024-12-05 Prabhat Kc , Rongping Zeng

X-ray Computed Tomography (CT) is an important tool in medical imaging to obtain a direct visualization of patient anatomy. However, the x-ray radiation exposure leads to the concern of lifetime cancer risk. Low-dose CT scan can reduce the…

Medical Physics · Physics 2018-10-30 Guoyang Ma , Chenyang Shen , Xun Jia

Like in many other research fields, recent developments in computational imaging have focused on developing machine learning (ML) approaches to tackle its main challenges. To improve the performance of computational imaging algorithms,…

Image and Video Processing · Electrical Eng. & Systems 2024-08-16 Maximilian B. Kiss , Ander Biguri , Carola-Bibiane Schönlieb , K. Joost Batenburg , Felix Lucka

Low dose computed tomography (LDCT) has attracted more and more attention in routine clinical diagnosis assessment, therapy planning, etc., which can reduce the dose of X-ray radiation to patients. However, the noise caused by low X-ray…

Image and Video Processing · Electrical Eng. & Systems 2021-07-06 Zhicheng Zhang , Lequan Yu , Xiaokun Liang , Wei Zhao , Lei Xing

A major challenge in computed tomography (CT) is to reduce X-ray dose to a low or even ultra-low level while maintaining the high quality of reconstructed images. We propose a new method for CT reconstruction that combines penalized…

Machine Learning · Statistics 2017-07-11 Xuehang Zheng , Zening Lu , Saiprasad Ravishankar , Yong Long , Jeffrey A. Fessler

Positron emission tomography (PET) is a critical tool for diagnosing tumors and neurological disorders but poses radiation risks to patients, particularly to sensitive populations. While reducing injected radiation dose mitigates this risk,…

Image and Video Processing · Electrical Eng. & Systems 2026-04-01 Yucun Hou , Fenglin Zhan , Xin Cheng , Chenxi Li , Ziquan Yuan , Runze Liao , Haihao Wang , Jianlang Hua , Jing Wu , Jianyong Jiang

Cross-dose denoising for low-dose positron emission tomography (LDPET) has been proposed to address the limited generalization of models trained at a single noise level. However, neural networks trained on a specific dose level often fail…

Computer Vision and Pattern Recognition · Computer Science 2026-05-18 Yichao Liu , Zongru Shao , Yueyang Teng , Junwen Guo

Deep-learning methods have shown promising performance for low-dose computed tomography (LDCT) reconstruction. However, supervised methods face the problem of lacking labeled data in clinical scenarios, and the CNN-based unsupervised…

Image and Video Processing · Electrical Eng. & Systems 2025-04-25 Ran An , Ke Chen , Hongwei Li

Low-dose CT images are essential for reducing radiation exposure in cancer screening, pediatric imaging, and longitudinal monitoring protocols, but their quality is often degraded by noise from low-dose acquisition, patient motion, or…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Jitindra Fartiyal , Pedro Freire , Sergei K. Turitsyn , Sergei G. Solovski

Spectral computed tomography (CT) has a great superiority in lesion detection, tissue characterization and material decomposition. To further extend its potential clinical applications, in this work, we propose an improved tensor dictionary…

Computer Vision and Pattern Recognition · Computer Science 2018-07-25 Weiwen Wu , Yanbo Zhang , Qian Wang , Fenglin Liu , Peijun Chen , Hengyong Yu

Low-dose computed tomography (CT) has attracted a major attention in the medical imaging field, since CT-associated x-ray radiation carries health risks for patients. The reduction of CT radiation dose, however, compromises the…

Computer Vision and Pattern Recognition · Computer Science 2019-07-16 Hongming Shan , Yi Zhang , Qingsong Yang , Uwe Kruger , Mannudeep K. Kalra , Ling Sun , Wenxiang Cong , Ge Wang