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Automated analysis of optical coherence tomography (OCT) and OCT angiography (OCTA) images is critical for robust ophthalmic diagnosis. Existing mainstream methods trained from scratch rely heavily on massive data and model scale, thereby…

Computer Vision and Pattern Recognition · Computer Science 2026-04-07 Xiaofei Su , Zengshuo Wang , Minghe Sun , Xin Zhao , Mingzhu Sun

Foundation models have revolutionized the paradigm of digital pathology, as they leverage general-purpose features to emulate real-world pathological practices, enabling the quantitative analysis of critical histological patterns and the…

Test-Time Adaptation (TTA) methods improve the robustness of deep neural networks to domain shift on a variety of tasks such as image classification or segmentation. This work explores adapting segmentation models to a single unlabelled…

Computer Vision and Pattern Recognition · Computer Science 2024-07-04 Klara Janouskova , Tamir Shor , Chaim Baskin , Jiri Matas

Fully Test-Time Adaptation (FTTA) addresses domain shifts without access to source data and training protocols of the pre-trained models. Traditional strategies that align source and target feature distributions are infeasible in FTTA due…

Machine Learning · Computer Science 2025-11-18 Ponhvoan Srey , Yaxin Shi , Hangwei Qian , Jing Li , Ivor W. Tsang

Foundation medical segmentation models, with MedSAM being the most popular, have achieved promising performance across organs and lesions. However, MedSAM still suffers from compromised performance on specific lesions with intricate…

Quantitative Methods · Quantitative Biology 2025-07-16 Kecheng Chen , Xinyu Luo , Tiexin Qin , Jie Liu , Hui Liu , Victor Ho Fun Lee , Hong Yan , Haoliang Li

Test-time adaptation (TTA) is an effective approach to mitigate performance degradation of trained models when encountering input distribution shifts at test time. However, existing TTA methods often suffer significant performance drops…

Machine Learning · Computer Science 2025-02-06 Minguk Jang , Hye Won Chung

Convolutional neural networks (CNNs) often suffer from poor performance when tested on target data that differs from the training (source) data distribution, particularly in medical imaging applications where variations in imaging protocols…

Computer Vision and Pattern Recognition · Computer Science 2024-02-28 Jingjie Guo , Weitong Zhang , Matthew Sinclair , Daniel Rueckert , Chen Chen

In computational pathology, deep learning (DL) models for tasks such as segmentation or tissue classification are known to suffer from domain shifts due to different staining techniques. Stain adaptation aims to reduce the generalization…

Image and Video Processing · Electrical Eng. & Systems 2024-07-04 Daniel Reisenbüchler , Lucas Luttner , Nadine S. Schaadt , Friedrich Feuerhake , Dorit Merhof

Visual anomaly detection targets to detect images that notably differ from normal pattern, and it has found extensive application in identifying defective parts within the manufacturing industry. These anomaly detection paradigms…

Computer Vision and Pattern Recognition · Computer Science 2024-11-15 Anindya Sundar Das , Guansong Pang , Monowar Bhuyan

In this study, we introduce an intelligent Test Time Augmentation (TTA) algorithm designed to enhance the robustness and accuracy of image classification models against viewpoint variations. Unlike traditional TTA methods that…

Image and Video Processing · Electrical Eng. & Systems 2024-06-14 Efe Ozturk , Mohit Prabhushankar , Ghassan AlRegib

Accurate liver segmentation from contrast-enhanced MRI is essential for diagnosis, treatment planning, and disease monitoring. However, it remains challenging due to limited annotated data, heterogeneous enhancement protocols, and…

Computer Vision and Pattern Recognition · Computer Science 2025-10-13 Jincan Lou , Jingkun Chen , Haoquan Li , Hang Li , Wenjian Huang , Weihua Chen , Fan Wang , Jianguo Zhang

The main challenge in domain generalization (DG) is to handle the distribution shift problem that lies between the training and test data. Recent studies suggest that test-time training (TTT), which adapts the learned model with test data,…

Computer Vision and Pattern Recognition · Computer Science 2023-04-18 Liang Chen , Yong Zhang , Yibing Song , Ying Shan , Lingqiao Liu

Continual Test-Time Adaptation (CTTA) aims to adapt the source model to continually changing unlabeled target domains without access to the source data. Existing methods mainly focus on model-based adaptation in a self-training manner, such…

Computer Vision and Pattern Recognition · Computer Science 2023-02-14 Yulu Gan , Yan Bai , Yihang Lou , Xianzheng Ma , Renrui Zhang , Nian Shi , Lin Luo

Deep learning advances have revolutionized automated digital pathology analysis. However, differences in staining protocols and imaging conditions can introduce significant color variability. In deep learning, such color inconsistency often…

Computer Vision and Pattern Recognition · Computer Science 2025-10-09 Tianyue Xu , Yanlin Wu , Abhai K. Tripathi , Matthew M. Ippolito , Benjamin D. Haeffele

Adversarial training (AT) can help improve the robustness of Vision Transformers (ViT) against adversarial attacks by intentionally injecting adversarial examples into the training data. However, this way of adversarial injection inevitably…

Computer Vision and Pattern Recognition · Computer Science 2024-07-23 Fudong Lin , Jiadong Lou , Xu Yuan , Nian-Feng Tzeng

Medical Foundation Models (MFMs), trained on large-scale datasets, have demonstrated superior performance across various tasks. However, these models still struggle with domain gaps in practical applications. Specifically, even after…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Jia-Xuan Jiang , Wenhui Lei , Yifeng Wu , Hongtao Wu , Furong Li , Yining Xie , Xiaofan Zhang , Zhong Wang

Recent continual test-time adaptation (CTTA) methods adopt masked image modeling to stabilize learning under distribution shift, yet each treats its masking family $F$ as a fixed design choice and innovates exclusively along the selection…

Unsupervised domain adaptation (UDA) for semantic segmentation is a promising task freeing people from heavy annotation work. However, domain discrepancies in low-level image statistics and high-level contexts compromise the segmentation…

Computer Vision and Pattern Recognition · Computer Science 2023-01-04 Haoyu Ma , Xiangru Lin , Yizhou Yu

Deep learning approaches to the segmentation of magnetic resonance images have shown significant promise in automating the quantitative analysis of brain images. However, a continuing challenge has been its sensitivity to the variability of…

Image and Video Processing · Electrical Eng. & Systems 2021-03-05 Dzung L. Pham , Yi-Yu Chou , Blake E. Dewey , Daniel S. Reich , John A. Butman , Snehashis Roy

Real-world application models are commonly deployed in dynamic environments, where the target domain distribution undergoes temporal changes. Continual Test-Time Adaptation (CTTA) has recently emerged as a promising technique to gradually…

Computer Vision and Pattern Recognition · Computer Science 2025-06-12 Shilei Cao , Juepeng Zheng , Yan Liu , Baoquan Zhao , Ziqi Yuan , Weijia Li , Runmin Dong , Haohuan Fu
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