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Empirical evaluation of breast tissue biopsies for mitotic nuclei detection is considered an important prognostic biomarker in tumor grading and cancer progression. However, automated mitotic nuclei detection poses several challenges…

Computer Vision and Pattern Recognition · Computer Science 2020-03-20 Anabia Sohail , Muhammad Ahsan Mukhtar , Asifullah Khan , Muhammad Mohsin Zafar , Aneela Zameer , Saranjam Khan

Scientific literature contains large volumes of complex, unstructured figures that are compound in nature (i.e. composed of multiple images, graphs, and drawings). Separation of these compound figures is critical for information retrieval…

Computer Vision and Pattern Recognition · Computer Science 2021-10-08 Weixin Jiang , Eric Schwenker , Trevor Spreadbury , Nicola Ferrier , Maria K. Y. Chan , Oliver Cossairt

In this paper we propose a workflow to detect and track mitotic cells in time-lapse microscopy image sequences. In order to avoid the requirement for cell lines expressing fluorescent markers and the associated phototoxicity, phase contrast…

Accurate detection of mitosis plays a critical role in breast cancer histopathology. Manual detection and counting of mitosis is tedious and subject to considerable inter- and intra-reader variations. Multispectral imaging is a recent…

Computer Vision and Pattern Recognition · Computer Science 2013-04-16 H. Irshad , A. Gouaillard , L. Roux , D. Racoceanu

Detection of mitosis events plays an important role in biomedical research. Deep-learning-based mitosis detection methods have achieved outstanding performance with a certain amount of labeled data. However, these methods require…

Computer Vision and Pattern Recognition · Computer Science 2023-07-11 Kazuya Nishimura , Ami Katanaya , Shinichiro Chuma , Ryoma Bise

Mitosis detection is one of the challenging problems in computational pathology, and mitotic count is an important index of cancer grading for pathologists. However, current counts of mitotic nuclei rely on pathologists looking…

Computer Vision and Pattern Recognition · Computer Science 2023-01-19 Huadeng Wang , Hao Xu , Bingbing Li , Xipeng Pan , Lingqi Zeng , Rushi Lan , Xiaonan Luo

Pathologist-defined labels are the gold standard for histopathological data sets, regardless of well-known limitations in consistency for some tasks. To date, some datasets on mitotic figures are available and were used for development of…

Computer Vision and Pattern Recognition · Computer Science 2020-10-22 Christof A. Bertram , Mitko Veta , Christian Marzahl , Nikolas Stathonikos , Andreas Maier , Robert Klopfleisch , Marc Aubreville

Studies estimate that there will be 266,120 new cases of invasive breast cancer and 40,920 breast cancer induced deaths in the year of 2018 alone. Despite the pervasiveness of this affliction, the current process to obtain an accurate…

Computer Vision and Pattern Recognition · Computer Science 2018-07-06 Siddhant Rao

Mitotic figures (MFs) are relevant biomarkers in tumor grading. Differentiating atypical MFs (AMFs) from normal MFs (NMFs) remains difficult, as manual annotation is time-consuming and subjective. In this work an ensemble of ConvNeXtBase…

Computer Vision and Pattern Recognition · Computer Science 2025-08-29 Sara Krauss , Ellena Spieß , Daniel Hieber , Frank Kramer , Johannes Schobel , Dominik Müller

Most recently, the pathology diagnosis of cancer is shifting to integrating molecular makers with histology features. It is a urgent need for digital pathology methods to effectively integrate molecular markers with histology, which could…

Image and Video Processing · Electrical Eng. & Systems 2023-06-28 Xiaofei Wang , Stephen Price , Chao Li

The difficulty of detecting mitosis and its similarity to non-mitosis objects has remained a challenge in computational pathology. The lack of publicly available data has added more complexity. Deep learning algorithms have shown potentials…

Image and Video Processing · Electrical Eng. & Systems 2021-10-25 Seyed H. Mirjahanmardi , Samir Mitha , Salar Razavi , Susan Done , April Khademi

This is a write-up of our method submitted to Mitosis Domain Generalization (MIDOG 2021) Challenge held in MICCAI2021 conference.

Image and Video Processing · Electrical Eng. & Systems 2021-09-06 Satoshi Kondo

In medical imaging, most of the image registration methods implicitly assume a one-to-one correspondence between the source and target images (i.e., diffeomorphism). However, this is not necessarily the case when dealing with pathological…

Image and Video Processing · Electrical Eng. & Systems 2022-02-03 Matthis Maillard , Anton François , Joan Glaunès , Isabelle Bloch , Pietro Gori

Over the past few years, the rapid development of deep learning technologies for computer vision has significantly improved the performance of medical image segmentation (MedISeg). However, the diverse implementation strategies of various…

Computer Vision and Pattern Recognition · Computer Science 2023-05-09 Dong Zhang , Yi Lin , Hao Chen , Zhuotao Tian , Xin Yang , Jinhui Tang , Kwang Ting Cheng

Recently, deep learning-based facial landmark detection for in-the-wild faces has achieved significant improvement. However, there are still challenges in face landmark detection in other domains (e.g. cartoon, caricature, etc). This is due…

Computer Vision and Pattern Recognition · Computer Science 2024-01-25 Yuanming Li , Gwantae Kim , Jeong-gi Kwak , Bon-hwa Ku , Hanseok Ko

Face morphing attack detection (MAD) is one of the most challenging tasks in the field of face recognition nowadays. In this work, we introduce a novel deep learning strategy for a single image face morphing detection, which implies the…

Computer Vision and Pattern Recognition · Computer Science 2022-08-08 Iurii Medvedev , Farhad Shadmand , Nuno Gonçalves

Causality has been combined with machine learning to produce robust representations for domain generalization. Most existing methods of this type require massive data from multiple domains to identify causal features by cross-domain…

Machine Learning · Computer Science 2024-03-01 Yang Chen , Yitao Liang , Zhouchen Lin

Machine learning models can perform well on in-distribution data but often fail on biased subgroups that are underrepresented in the training data, hindering the robustness of models for reliable applications. Such subgroups are typically…

Computer Vision and Pattern Recognition · Computer Science 2024-03-22 Zeliang Zhang , Mingqian Feng , Zhiheng Li , Chenliang Xu

Mitotic count (MC) is an important histological parameter for cancer diagnosis and grading, but the manual process for obtaining MC from whole-slide histopathological images is very time-consuming and prone to error. Therefore, deep…

Computer Vision and Pattern Recognition · Computer Science 2022-03-01 Chawan Piansaddhayanon , Sakun Santisukwongchote , Shanop Shuangshoti , Qingyi Tao , Sira Sriswasdi , Ekapol Chuangsuwanich

Despite outstanding performance on public benchmarks, face recognition still suffers due to domain mismatch between training (source) and testing (target) data. Furthermore, these domains are not shared classes, which complicates domain…

Computer Vision and Pattern Recognition · Computer Science 2021-04-09 Chun-Hsien Lin , Bing-Fei Wu