Related papers: Robust Pan-Cancer Mitotic Figure Detection with YO…
In certain types of cancerous tissue, mitotic count has been shown to be associated with tumor proliferation, poor prognosis, and therapeutic resistance. Due to the high inter-rater variability of mitotic counting by pathologists,…
This paper describes our contribution to the MIDOG 2022 challenge for detecting mitotic cells. One of the major problems to be addressed in the MIDOG 2022 challenge is the robustness under the natural variance that appears for real-life…
Accurate mitotic figure classification is crucial in computational pathology, as mitotic activity informs cancer grading and patient prognosis. Distinguishing atypical mitotic figures (AMFs), which indicate higher tumor aggressiveness, from…
Automated detection of mitotic figures in histopathology images has seen vast improvements, thanks to modern deep learning-based pipelines. Application of these methods, however, is in practice limited by strong variability of images…
Mitotic activity is a crucial proliferation biomarker for the diagnosis and prognosis of different types of cancers. Nevertheless, mitosis counting is a cumbersome process for pathologists, prone to low reproducibility, due to the large…
Mitotic activity is key for the assessment of malignancy in many tumors. Moreover, it has been demonstrated that the proportion of abnormal mitosis to normal mitosis is of prognostic significance. Atypical mitotic figures (MF) can be…
Counting mitotic figures is time-intensive for pathologists and leads to inter-observer variability. Artificial intelligence (AI) promises a solution by automatically detecting mitotic figures while maintaining decision consistency.…
Breast cancer is the most commonly diagnosed cancer worldwide, with over two million new cases each year. During diagnostic tumour grading, pathologists manually count the number of dividing cells (mitotic figures) in biopsy or tumour…
Recognizing atypical mitotic figures in histopathology images allows physicians to correctly assess tumor aggressiveness. Although machine learning models could be exploited for automatically performing such a task, under domain shift these…
Studies estimate that there will be 266,120 new cases of invasive breast cancer and 40,920 breast cancer induced deaths in the year of 2018 alone. Despite the pervasiveness of this affliction, the current process to obtain an accurate…
Mitotic counting is a vital prognostic marker of tumor proliferation in breast cancer. Deep learning-based mitotic detection is on par with pathologists, but it requires large labeled data for training. We propose a deep classification…
The effective localization of mitosis is a critical precursory task for deciding tumor prognosis and grade. Automated mitosis detection through deep learning-oriented image analysis often fails on unseen patient data due to inherent domain…
We propose a new training scheme for domain generalization in mitotic figure detection. Mitotic figures show different characteristics for each scanner. We consider each scanner as a 'domain' and the image distribution specified for each…
Empirical evaluation of breast tissue biopsies for mitotic nuclei detection is considered an important prognostic biomarker in tumor grading and cancer progression. However, automated mitotic nuclei detection poses several challenges…
Atypical mitotic figures (AMFs) represent abnormal cell division associated with poor prognosis. Yet their detection remains difficult due to low prevalence, subtle morphology, and inter-observer variability. The MIDOG 2025 challenge…
Motivation: Accurate classification of mitotic figures into normal and atypical types is crucial for tumor prognostication in digital pathology. However, developing robust deep learning models for this task is challenging due to the subtle…
The account of mitotic cells is a key feature in tumor diagnosis. However, due to the variability of mitotic cell morphology, it is a highly challenging task to detect mitotic cells in tumor tissues. At the same time, although advanced deep…
MIDOG 2025 Track 1 requires mitosis detection in whole-slideimages (WSIs) containing non-tumor, inflamed, and necrotic re-gions. Due to the complicated and heterogeneous context, aswell as possible artifacts, there are often false positives…
For histopathological tumor assessment, the count of mitotic figures per area is an important part of prognostication. Algorithmic approaches - such as for mitotic figure identification - have significantly improved in recent times,…
Assessing the Mitotic Count has a known high degree of intra- and inter-rater variability. Computer-aided systems have proven to decrease this variability and reduce labeling time. These systems, however, are generally highly dependent on…