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Dichotomous Image Segmentation (DIS) tasks require highly precise annotations, and traditional dataset creation methods are labor intensive, costly, and require extensive domain expertise. Although using synthetic data for DIS is a…

Computer Vision and Pattern Recognition · Computer Science 2024-12-30 Haotian Qian , YD Chen , Shengtao Lou , Fahad Shahbaz Khan , Xiaogang Jin , Deng-Ping Fan

A major challenges of deep learning (DL) is the necessity to collect huge amounts of training data. Often, the lack of a sufficiently large dataset discourages the use of DL in certain applications. Typically, acquiring the required amounts…

Computer Vision and Pattern Recognition · Computer Science 2024-10-31 Andoni Cortés , Clemente Rodríguez , Gorka Velez , Javier Barandiarán , Marcos Nieto

Deep Learning (DL) models have been successfully applied to many applications including biomedical cell segmentation and classification in histological images. These models require large amounts of annotated data which might not always be…

Image and Video Processing · Electrical Eng. & Systems 2024-06-04 Roberto Basla , Loris Giulivi , Luca Magri , Giacomo Boracchi

Recent advances in high-throughput sequencing technologies have enabled the extraction of multiple features that depict patient samples at diverse and complementary molecular levels. The generation of such data has led to new challenges in…

Genomics · Quantitative Biology 2022-09-14 Hakim Benkirane , Yoann Pradat , Stefan Michiels , Paul-Henry Cournède

To acquire a new skill, humans learn better and faster if a tutor, based on their current knowledge level, informs them of how much attention they should pay to particular content or practice problems. Similarly, a machine learning model…

Machine Learning · Computer Science 2021-06-18 Xinyi Wang , Hieu Pham , Paul Michel , Antonios Anastasopoulos , Jaime Carbonell , Graham Neubig

Histopathological prognostication of neoplasia including most tumor grading systems are based upon a number of criteria. Probably the most important is the number of mitotic figures which are most commonly determined as the mitotic count…

Computer Vision and Pattern Recognition · Computer Science 2020-01-06 Marc Aubreville , Christof A. Bertram , Robert Klopfleisch , Andreas Maier

Active learning is a unique abstraction of machine learning techniques where the model/algorithm could guide users for annotation of a set of data points that would be beneficial to the model, unlike passive machine learning. The primary…

Computer Vision and Pattern Recognition · Computer Science 2021-01-08 Vishwesh Nath , Dong Yang , Bennett A. Landman , Daguang Xu , Holger R. Roth

Histopathology image analysis can be considered as a Multiple instance learning (MIL) problem, where the whole slide histopathology image (WSI) is regarded as a bag of instances (i.e, patches) and the task is to predict a single class label…

Computer Vision and Pattern Recognition · Computer Science 2019-06-28 Meng Li , Lin Wu , Arnold Wiliem , Kun Zhao , Teng Zhang , Brian C. Lovell

Heterogeneous networks are widely used to model real-world semi-structured data. The key challenge of learning over such networks is the modeling of node similarity under both network structures and contents. To deal with network…

Social and Information Networks · Computer Science 2019-10-04 Carl Yang , Mengxiong Liu , Frank He , Xikun Zhang , Jian Peng , Jiawei Han

Meta learning aims at learning how to solve tasks, and thus it allows to estimate models that can be quickly adapted to new scenarios. This work explores distributionally robust minimization in meta learning for system identification.…

Machine Learning · Computer Science 2025-06-24 Matteo Rufolo , Dario Piga , Marco Forgione

Exponential growth in Electronic Healthcare Records (EHR) has resulted in new opportunities and urgent needs for discovery of meaningful data-driven representations and patterns of diseases in Computational Phenotyping research. Deep…

Machine Learning · Statistics 2015-12-14 Zhengping Che , Sanjay Purushotham , Robinder Khemani , Yan Liu

We present a pioneering investigation into the application of deep learning techniques to analyze histopathological images for addressing the substantial challenge of automated prognostic prediction. Prognostic prediction poses a unique…

Mitosis count is an important biomarker for prognosis of various cancers. At present, pathologists typically perform manual counting on a few selected regions of interest in breast whole-slide-images (WSIs) of patient biopsies. This task is…

Computer Vision and Pattern Recognition · Computer Science 2018-08-01 Saad Ullah Akram , Talha Qaiser , Simon Graham , Juho Kannala , Janne Heikkilä , Nasir Rajpoot

With the rising number of machine learning competitions, the world has witnessed an exciting race for the best algorithms. However, the involved data selection process may fundamentally suffer from evidence ambiguity and concept drift…

Machine Learning · Computer Science 2020-06-15 Hoang D. Nguyen , Xuan-Son Vu , Quoc-Tuan Truong , Duc-Trong Le

Melanoma detection is vital for early diagnosis and effective treatment. While deep learning models on dermoscopic images have shown promise, they require specialized equipment, limiting their use in broader clinical settings. This study…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Volodymyr Sydorskyi , Igor Krashenyi , Oleksii Yakubenko

Self-supervised pre-training of deep learning models with contrastive learning is a widely used technique in image analysis. Current findings indicate a strong potential for contrastive pre-training on medical images. However, further…

Image and Video Processing · Electrical Eng. & Systems 2024-10-21 Daniel Wolf , Tristan Payer , Catharina Silvia Lisson , Christoph Gerhard Lisson , Meinrad Beer , Michael Götz , Timo Ropinski

Few-shot learning is a standard practice in most deep learning based histopathology image segmentation, given the relatively low number of digitized slides that are generally available. While many models have been developed for domain…

Image and Video Processing · Electrical Eng. & Systems 2021-10-01 Zheng Yuan , Andre Esteva , Ran Xu

The lack of sufficient annotated image data is a common issue in medical image segmentation. For some organs and densities, the annotation may be scarce, leading to poor model training convergence, while other organs have plenty of…

Image and Video Processing · Electrical Eng. & Systems 2021-09-22 Anastasia Makarevich , Azade Farshad , Vasileios Belagiannis , Nassir Navab

Deep learning methods have shown promise in classifying breast cancer histopathology images, but their performance often declines with limited annotated data, a critical challenge in medical imaging due to the high cost and expertise…

Computer Vision and Pattern Recognition · Computer Science 2025-05-08 Liu Suxing , Byungwon Min

Annotations are necessary to develop computer vision algorithms for histopathology, but dense annotations at a high resolution are often time-consuming to make. Deep learning models for segmentation are a way to alleviate the process, but…

Computer Vision and Pattern Recognition · Computer Science 2022-11-15 Eduard Chelebian , Francesco Ciompi , Carolina Wählby