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Cardiovascular disease affects millions of people worldwide and its social and economic cost clearly motivates scientific research. Computer simulation can lead to a better understanding of cardiac physiology, and for pathology presents…

Biological Physics · Physics 2023-02-27 Toby Simpson

Real-time monitoring of the gastrointestinal tract in a safe and comfortable manner is valuable for the diagnosis and therapy of many diseases. Within this realm, our review captures the trends in ingestible capsule systems with a focus on…

Developing clinically viable tissue-engineered cardiovascular implants remains a formidable challenge. Achieving reliable and durable outcomes requires a deeper understanding of the fundamental mechanisms driving tissue evolution during in…

Computational Engineering, Finance, and Science · Computer Science 2025-07-29 Mahmoud Sesa , Hagen Holthusen , Christian Böhm , Stefan Jockenhövel , Stefanie Reese , Kevin Linka

The standard engineering approach when facing uncertainty is modelling. Mixing data from a well-calibrated model with real recordings has led to breakthroughs in many applications of AI, from computer vision to autonomous driving. This type…

Quantitative Methods · Quantitative Biology 2026-03-10 Balint K. Hodossy , Dario Farina

In this study we present a novel computational model for unprecedented simulations of the whole cardiac electrophysiology. According to the heterogeneous electrophysiologic properties of the heart, the whole cardiac geometry is decomposed…

Medical Physics · Physics 2022-03-14 Giulio Del Corso , Roberto Verzicco , Francesco Viola

Computational models of atrial electrophysiology (EP) are increasingly utilized for applications such as the development of advanced mapping systems, personalized clinical therapy planning, and the generation of virtual cohorts and digital…

Electrospinning has exhibited excellent benefits to treat the trauma for tissue engineering due to its produced micro/nano fibrous structure. It can effectively adhere to the tissue surface for long-term continuous therapy. This paper…

Robotics · Computer Science 2021-06-08 Zicong Wu , Chuqian Lou , Zhu Jin , Shaoping Huang , Ning Liu , Yun Zou , Mirko Kovac , Anzhu Gao , Guang-Zhong Yang

Developing new methods for predicting electromagnetic instabilities in cardiac activity is of primary importance. However, we still need a comprehensive view of the heart's magnetic activity at the tissue scale. To fill this gap, we present…

While data-driven methods offer significant promise for modeling complex materials, they often face challenges in generalizing across diverse physical scenarios and maintaining physical consistency. To address these limitations, we propose…

Graphics · Computer Science 2025-10-27 Xueguang Xie , Shu Yan , Shiwen Jia , Siyu Yang , Aimin Hao , Yang Gao , Peng Yu

With the increasing of computer capabilities, Computer aided ergonomics (CAE) offers new possibilities to integrate conventional ergonomic knowledge and to develop new methods into the work design process. As mentioned in [1], different…

Robotics · Computer Science 2011-04-06 Ruina Ma , Damien Chablat , Fouad Bennis , Liang Ma

Magnetic resonance elastography is a motion-sensitive image modality that allows to measure in vivo tissue displacement fields in response to mechanical excitations. This paper investigates a data assimilation approach for reconstructing…

We present a whole-body model of human metabolism that utilizes a system of organs and blood vessels to simulate the enzymatic reactions. The model focuses on key organs, including the brain, heart and lungs, liver, gut, and kidney, as well…

Quantitative Methods · Quantitative Biology 2023-08-01 Jacob Bendsen , Peter Emil Carstensen , Asbjørn Thode Reenberg , Tobias K. S. Ritschel , John Bagterp Jørgensen

In this paper we introduce a new mathematical model for the active contraction of cardiac muscle, featuring different thermo-electric and nonlinear conductivity properties. The passive hyperelastic response of the tissue is described by an…

Tissues and Organs · Quantitative Biology 2019-05-02 Ricardo Ruiz Baier , Alessio Gizzi , Alessandro Loppini , Christian Cherubini , Simonetta Filippi

In this paper, a 3D discrete model is presented to model the movements of the trunk during breathing. In this model, objects are represented by physical particles on their contours. A simple notion of force generated by a linear actuator…

Medical Physics · Physics 2008-08-05 Emmanuel Promayon , Pierre Baconnier

Diagnosing esophageal motility disorders pose significant challenges due to the complexity of high-resolution impedance manometry (HRIM) data and variability in clinical interpretation. This work explores the feasibility of a multimodal…

Machine Learning · Computer Science 2026-05-14 Alexander Geiger , Lars Wagner , Daniel Rueckert , Alois Knoll , Dirk Wilhelm , Alissa Jell

EMU is an efficient and scalable model to simulate bulk musculoskeletal motion with heterogenous materials. First, EMU requires no model reductions, or geometric coarsening, thereby producing results visually accurate when compared to an…

Graphics · Computer Science 2020-11-20 Vismay Modi , Lawson Fulton , Shinjiro Sueda , Alec Jacobson , David I. W. Levin

Electromyography (EMG) signals are obtained from muscle cell activity. The recording and analysis of EMG signals has several applications. The EMG is of diagnostic importance for treating patients suffering from neurological and…

Systems and Control · Electrical Eng. & Systems 2025-09-18 Vinay C K , Vikas Vazhayil , Madhav rao

We present a new approach for physics-based computational modeling of diseased human lungs. Our main object is the development of a model that takes the novel step of incorporating the dynamics of airway recruitment/de-recruitment into an…

Computational Engineering, Finance, and Science · Computer Science 2023-05-10 Carolin M. Geitner , Tobias Becher , Inéz Frerichs , Norbert Weiler , Jason H. T. Bates , Wolfgang A. Wall

Mucus is a biological gel covering the surface of several tissues and insuring key biological functions, including as a protective barrier against dehydration, pathogens penetration, or gastric acids. Mucus biological functioning requires a…

Soft Condensed Matter · Physics 2022-01-05 Domenico Larobina , Angelo Pommella , Adrian-Marie Philippe , Med Yassine Nagazi , Luca Cipelletti
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