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The integration of large language models (LLMs) into medical practice offers transformative potential, yet their real-world clinical applicability remains constrained by critical alignment issues: (1) a misalignment between static…

Artificial Intelligence · Computer Science 2025-12-05 Yongnan Jin , Xurui Li , Feng Cao , Liucun Gao , Juanjuan Yao

The integration of Artificial Intelligence (AI), especially Large Language Models (LLMs), into the clinical diagnosis process offers significant potential to improve the efficiency and accessibility of medical care. While LLMs have shown…

Computation and Language · Computer Science 2024-10-15 Mingyu Derek Ma , Chenchen Ye , Yu Yan , Xiaoxuan Wang , Peipei Ping , Timothy S Chang , Wei Wang

Medical conversational AI (AI) plays a pivotal role in the development of safer and more effective medical dialogue systems. However, existing benchmarks and evaluation frameworks for assessing the information-gathering and diagnostic…

Computation and Language · Computer Science 2026-01-08 Lecheng Gong , Weimin Fang , Ting Yang , Dongjie Tao , Chunxiao Guo , Peng Wei , Bo Xie , Jinqun Guan , Zixiao Chen , Fang Shi , Jinjie Gu , Junwei Liu

Multimodal Large Language Models (MLLMs) have achieved impressive performances in mathematical reasoning, yet they remain vulnerable to visual hallucinations and logical inconsistencies that standard outcome-based supervision fails to…

Artificial Intelligence · Computer Science 2026-01-01 Peng Kuang , Xiangxiang Wang , Wentao Liu , Jian Dong , Kaidi Xu

Recent developments in Large Language Model (LLM)-based agents have shown impressive capabilities spanning multiple domains, exemplified by deep research systems that demonstrate superior performance on complex information-seeking and…

Computation and Language · Computer Science 2025-09-03 Ailing Yu , Lan Yao , Jingnan Liu , Zhe Chen , Jiajun Yin , Yuan Wang , Xinhao Liao , Zhiling Ye , Ji Li , Yun Yue , Hansong Xiao , Hualei Zhou , Chunxiao Guo , Peng Wei , Junwei Liu , Jinjie Gu

Ensuring the safety and reliability of large language models (LLMs) in clinical practice is critical to prevent patient harm. However, LLMs are advancing so rapidly that static benchmarks quickly become obsolete or prone to overfitting,…

Large Language Models (LLMs) have shown strong capabilities through two complementary paradigms: Retrieval-Augmented Generation (RAG) for knowledge grounding and Reinforcement Learning from Verifiable Rewards (RLVR) for complex reasoning.…

Computation and Language · Computer Science 2026-04-27 Weitao Li , Boran Xiang , Xiaolong Wang , Zhinan Gou , Weizhi Ma , Yang Liu

Multimodal large language models (MLLMs), which integrate language and visual cues for problem-solving, are crucial for advancing artificial general intelligence (AGI). However, current benchmarks for measuring the intelligence of MLLMs…

Multimodal Large Language Models (MLLMs) have demonstrated impressive capabilities in understanding common visual elements, largely due to their large-scale datasets and advanced training strategies. However, their effectiveness in medical…

Traditional Chinese Medicine (TCM) is a holistic medical system with millennia of accumulated clinical experience, playing a vital role in global healthcare-particularly across East Asia. However, the implicit reasoning, diverse textual…

Computation and Language · Computer Science 2025-06-03 Shufeng Kong , Xingru Yang , Yuanyuan Wei , Zijie Wang , Hao Tang , Jiuqi Qin , Shuting Lan , Yingheng Wang , Junwen Bai , Zhuangbin Chen , Zibin Zheng , Caihua Liu , Hao Liang

Large vision-language models (LVMs) hold a great promise for automating medical report generation, potentially reducing the burden of manual reporting. State-of-the-art (SOTA) research fine-tunes general LVMs with medical data to align…

Computation and Language · Computer Science 2025-04-07 Hao Wang , Shuchang Ye , Jinghao Lin , Usman Naseem , Jinman Kim

Large Language Models (LLMs) has made significant progress in a number of professional fields, including medicine, law, and finance. However, in traditional Chinese medicine (TCM), there are challenges such as the essential differences…

Computation and Language · Computer Science 2024-06-25 Heyi Zhang , Xin Wang , Zhaopeng Meng , Zhe Chen , Pengwei Zhuang , Yongzhe Jia , Dawei Xu , Wenbin Guo

The adoption of large language models (LLMs) to assist clinicians has attracted remarkable attention. Existing works mainly adopt the close-ended question-answering (QA) task with answer options for evaluation. However, many clinical…

Medical Decision-Making (MDM) is a multi-faceted process that requires clinicians to assess complex multi-modal patient data patient, often collaboratively. Large Language Models (LLMs) promise to streamline this process by synthesizing…

We introduce MediX-R1, an open-ended Reinforcement Learning (RL) framework for medical multimodal large language models (MLLMs) that enables clinically grounded, free-form answers beyond multiple-choice formats. MediX-R1 fine-tunes a…

Computer Vision and Pattern Recognition · Computer Science 2026-02-27 Sahal Shaji Mullappilly , Mohammed Irfan Kurpath , Omair Mohamed , Mohamed Zidan , Fahad Khan , Salman Khan , Rao Anwer , Hisham Cholakkal

The transition of Large Language Models (LLMs) from passive knowledge retrievers to autonomous clinical agents demands a shift in evaluation-from static accuracy to dynamic behavioral reliability. To explore this boundary in dentistry, a…

Computation and Language · Computer Science 2026-01-21 Hongyang Ma , Tiantian Gu , Huaiyuan Sun , Huilin Zhu , Yongxin Wang , Jie Li , Wubin Sun , Zeliang Lian , Yinghong Zhou , Yi Gao , Shirui Wang , Zhihui Tang

Large Language Models (LLMs) have demonstrated remarkable proficiency in human interactions, yet their application within the medical field remains insufficiently explored. Previous works mainly focus on the performance of medical knowledge…

Computation and Language · Computer Science 2024-07-23 Yusheng Liao , Yutong Meng , Yuhao Wang , Hongcheng Liu , Yanfeng Wang , Yu Wang

The surge of large language models (LLMs) has driven significant progress in medical applications, including traditional Chinese medicine (TCM). However, current medical LLMs struggle with TCM diagnosis and syndrome differentiation due to…

Computation and Language · Computer Science 2025-10-01 Sibo Wei , Xueping Peng , Yi-Fei Wang , Tao Shen , Jiasheng Si , Weiyu Zhang , Fa Zhu , Athanasios V. Vasilakos , Wenpeng Lu , Xiaoming Wu , Yinglong Wang

Recent advances in vision-language models (VLMs) have achieved remarkable performance on standard medical benchmarks, yet their true clinical reasoning ability remains unclear. Existing datasets predominantly emphasize classification…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Miao Jing , Mengting Jia , Junling Lin , Zhongxia Shen , Huan Gao , Mingkun Xu , Shangyang Li

Large language model (LLM)-based reasoning systems have recently achieved gold medal-level performance in the IMO 2025 competition, writing mathematical proofs where, to receive full credit, each step must be not only correct but also…

Artificial Intelligence · Computer Science 2025-10-16 Shrey Pandit , Austin Xu , Xuan-Phi Nguyen , Yifei Ming , Caiming Xiong , Shafiq Joty
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