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We present a comprehensive, novel framework for understanding how the neocortex, including the thalamocortical loops through the deep layers, can support a temporal context representation in the service of predictive learning. Many have…

Neurons and Cognition · Quantitative Biology 2014-07-15 Randall C. O'Reilly , Dean Wyatte , John Rohrlich

Dense Associative Memories or Modern Hopfield Networks have many appealing properties of associative memory. They can do pattern completion, store a large number of memories, and can be described using a recurrent neural network with a…

Neural and Evolutionary Computing · Computer Science 2021-07-29 Dmitry Krotov

Sequential firing of hippocampal place cells is often attributed to sequential sensory drive along a trajectory, and has also been attributed to planning and other cognitive functions. Here, we propose a mechanistic and parsimonious…

Neurons and Cognition · Quantitative Biology 2026-03-03 Xiao-Xiong Lin , Yuk-Hoi Yiu , Christian Leibold

Information encoding in the nervous system is supported through the precise spike-timings of neurons; however, an understanding of the underlying processes by which such representations are formed in the first place remains unclear. Here we…

Neural and Evolutionary Computing · Computer Science 2015-12-01 Brian Gardner , Ioana Sporea , André Grüning

Recognition of objects from partial information presents a significant challenge for theories of vision because it requires spatial integration and extrapolation from prior knowledge. We combined neurophysiological recordings in human…

Neurons and Cognition · Quantitative Biology 2014-09-11 Hanlin Tang , Calin Buia , Joseph Madsen , William S. Anderson , Gabriel Kreiman

Episodic memory is a psychology term which refers to the ability to recall specific events from the past. We suggest one advantage of this particular type of memory is the ability to easily assign credit to a specific state when remembered…

Machine Learning · Computer Science 2018-06-05 Kenny J. Young , Richard S. Sutton , Shuo Yang

Despite substantial research into the biological basis of memory, the precise mechanisms by which experiences are encoded, stored, and retrieved in the brain remain incompletely understood. A growing body of evidence supports the engram…

Neural and Evolutionary Computing · Computer Science 2025-10-28 Daniel Szelogowski

Knowledge graphs are an expressive and widely used data structure due to their ability to integrate data from different domains in a sensible and machine-readable way. Thus, they can be used to model a variety of systems such as molecules…

Neural and Evolutionary Computing · Computer Science 2023-08-28 Dominik Dold , Josep Soler Garrido , Victor Caceres Chian , Marcel Hildebrandt , Thomas Runkler

In this paper we propose the CTS (Concious Tutoring System) technology, a biologically plausible cognitive agent based on human brain functions.This agent is capable of learning and remembering events and any related information such as…

Artificial Intelligence · Computer Science 2009-02-02 Usef Faghihi , Philippe Fournier-Viger , Roger Nkambou , Pierre Poirier , Andre Mayers

Episodic memory lets reinforcement learning algorithms remember and exploit promising experience from the past to improve agent performance. Previous works on memory mechanisms show benefits of using episodic-based data structures for…

Machine Learning · Computer Science 2021-06-17 Igor Kuznetsov , Andrey Filchenkov

The hippocampal formation is thought to learn spatial maps of environments, and in many models this learning process consists of forming a sensory association for each location in the environment. This is inefficient, akin to learning a…

Artificial Intelligence · Computer Science 2021-07-02 Marcus Lewis

Understanding the intricate operations of Recurrent Neural Networks (RNNs) mechanistically is pivotal for advancing their capabilities and applications. In this pursuit, we propose the Episodic Memory Theory (EMT), illustrating that RNNs…

Neural and Evolutionary Computing · Computer Science 2023-10-05 Arjun Karuvally , Peter Delmastro , Hava T. Siegelmann

Both neurophysiological and psychophysical experiments have pointed out the crucial role of recurrent and feedback connections to process context-dependent information in the early visual cortex. While numerous models have accounted for…

Computer Vision and Pattern Recognition · Computer Science 2019-10-18 Victor Boutin , Angelo Franciosini , Frederic Chavane , Franck Ruffier , Laurent Perrinet

Deep learning for medical imaging suffers from temporal and privacy-related restrictions on data availability. To still obtain viable models, continual learning aims to train in sequential order, as and when data is available. The main…

Image and Video Processing · Electrical Eng. & Systems 2021-07-27 Marius Memmel , Camila Gonzalez , Anirban Mukhopadhyay

In order for large language models to achieve true conversational continuity and benefit from experiential learning, they need memory. While research has focused on the development of complex memory systems, it remains unclear which types…

Computation and Language · Computer Science 2025-12-09 Alessandra Terranova , Björn Ross , Alexandra Birch

Human learning relies on specialization -- distinct cognitive mechanisms working together to enable rapid learning. In contrast, most modern neural networks rely on a single mechanism: gradient descent over an objective function. This…

Machine Learning · Computer Science 2025-05-16 Daniel Weitekamp , Christopher MacLellan , Erik Harpstead , Kenneth Koedinger

Encoding models that predict brain response patterns to stimuli are one way to capture this relationship between variability in bottom-up neural systems and individual's behavior or pathological state. However, they generally need a large…

Quantitative Methods · Quantitative Biology 2022-05-17 Zijin Gu , Keith Jamison , Mert Sabuncu , Amy Kuceyeski

The human ability to flexibly reason using analogies with domain-general content depends on mechanisms for identifying relations between concepts, and for mapping concepts and their relations across analogs. Building on a recent model of…

Artificial Intelligence · Computer Science 2021-10-06 Hongjing Lu , Nicholas Ichien , Keith J. Holyoak

Top-down feedback in cortex is critical for guiding sensory processing, which has prominently been formalized in the theory of hierarchical predictive coding (hPC). However, experimental evidence for error units, which are central to the…

Neurons and Cognition · Quantitative Biology 2022-11-23 Fabian A. Mikulasch , Lucas Rudelt , Michael Wibral , Viola Priesemann

The human brain constantly learns and rapidly adapts to new situations by integrating acquired knowledge and experiences into memory. Developing this capability in machine learning models is considered an important goal of AI research since…

Artificial Intelligence · Computer Science 2023-06-08 Arsham Gholamzadeh Khoee , Alireza Javaheri , Saeed Reza Kheradpisheh , Mohammad Ganjtabesh
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