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Whole genome sequencing of pathogens from multiple hosts in an epidemic offers the potential to investigate who infected whom with unparalleled resolution, potentially yielding important insights into disease dynamics and the impact of…

To understand the contact patterns of a population -- who is in contact with whom, and when the contacts happen -- is crucial for modeling outbreaks of infectious disease. Traditional theoretical epidemiology assumes that any individual can…

Populations and Evolution · Quantitative Biology 2015-10-22 Petter Holme

The behavior of ecological systems mainly relies on the interactions between the species it involves. We consider the problem of inferring the species interaction network from abundance data. To be relevant, any network inference…

Applications · Statistics 2019-10-29 Raphaëlle Momal , Stéphane Robin , Christophe Ambroise

We propose a generative model and an inference scheme for epidemic processes on dynamic, adaptive contact networks. Network evolution is formulated as a link-Markovian process, which is then coupled to an individual-level stochastic SIR…

Methodology · Statistics 2020-04-07 Fan Bu , Allison E. Aiello , Jason Xu , Alexander Volfovsky

A stochastic epidemic model is defined in which each individual belongs to a household, a secondary grouping (typically school or workplace) and also the community as a whole. Moreover, infectious contacts take place in these three settings…

Applications · Statistics 2009-08-17 Tom Britton , Theodore Kypraios , Philip O'Neill

Reconstructing who infected whom is a central challenge in analysing epidemiological data. Recently, advances in sequencing technology have led to increasing interest in Bayesian approaches to inferring who infected whom using genetic data…

Quantitative Methods · Quantitative Biology 2016-09-30 Michelle Kendall , Diepreye Ayabina , Caroline Colijn

The spread of infectious disease in a human community or the proliferation of fake news on social media can be modeled as a randomly growing tree-shaped graph. The history of the random growth process is often unobserved but contains…

Probability · Mathematics 2021-01-15 Harry Crane , Min Xu

Many progresses in the understanding of epidemic spreading models have been obtained thanks to numerous modeling efforts and analytical and numerical studies, considering host populations with very different structures and properties,…

Physics and Society · Physics 2018-02-02 Antoine Moinet , Alain Barrat , Romualdo Pastor Satorras

Infectious diseases are studied to understand their spreading mechanisms, to evaluate control strategies and to predict the risk and course of future outbreaks. Because people only interact with a small number of individuals, and because…

Applications · Statistics 2018-09-05 Ritabrata Dutta , Antonietta Mira , Jukka-Pekka Onnela

The networked structure of contacts shapes the spreading of epidemic processes. Recent advances on network theory have improved our understanding of the epidemic processes at large scale. The relevance of several considerations still needs…

Physics and Society · Physics 2019-02-21 Sergio Gómez , Alberto Fernández , Sandro Meloni , Alex Arenas

Network--based epidemic models that account for heterogeneous contact patterns are extensively used to predict and control the diffusion of infectious diseases. We use census and survey data to reconstruct a geo--referenced and…

Social and Information Networks · Computer Science 2026-05-19 Alessandro Celestini , Francesca Colaiori , Stefano Guarino , Enrico Mastrostefano , Lena Rebecca Zastrow

Recent work has attempted to use whole-genome sequence data from pathogens to reconstruct the transmission trees linking infectors and infectees in outbreaks. However, transmission trees from one outbreak do not generalize to future…

Quantitative Methods · Quantitative Biology 2023-10-24 Eben Kenah , Tom Britton , M. Elizabeth Halloran , Ira M. Longini

Throughout the course of an epidemic, the rate at which disease spreads varies with behavioral changes, the emergence of new disease variants, and the introduction of mitigation policies. Estimating such changes in transmission rates can…

Methodology · Statistics 2022-11-29 Jenny Huang , Raphaël Morsomme , David Dunson , Jason Xu

We develop a stochastic epidemic model progressing over dynamic networks, where infection rates are heterogeneous and may vary with individual-level covariates. The joint dynamics are modeled as a continuous-time Markov chain such that…

Methodology · Statistics 2021-12-16 Fan Bu , Allison E. Aiello , Alexander Volfovsky , Jason Xu

Global transport and communication networks enable information, ideas and infectious diseases now to spread at speeds far beyond what has historically been possible. To effectively monitor, design, or intervene in such epidemic-like…

Physics and Society · Physics 2020-02-13 Sam Moore , Tim Rogers

Consider stochastic models for the spread of an infection in a structured community, where this structured community is itself described by a random network model. Some common network models and transmission models are defined and large…

Populations and Evolution · Quantitative Biology 2019-08-16 Tom Britton

The time variation of contacts in a networked system may fundamentally alter the properties of spreading processes and affect the condition for large-scale propagation, as encoded in the epidemic threshold. Despite the great interest in the…

Physics and Society · Physics 2015-04-14 Eugenio Valdano , Luca Ferreri , Chiara Poletto , Vittoria Colizza

Mathematical models of infectious diseases, which are in principle analytically tractable, use two general approaches. The first approach, generally known as compartmental modeling, addresses the time evolution of disease propagation at the…

Populations and Evolution · Quantitative Biology 2010-09-16 Pierre-André Noël , Bahman Davoudi , Robert C. Brunham , Louis J. Dubé , Babak Pourbohloul

The epidemic spreading of a disease can be described by a contact network whose nodes are persons or centers of contagion and links heterogeneous relations among them. We provide a procedure to identify multiple sources of an outbreak or…

Mathematical Physics · Physics 2012-11-13 Vincenzo Fioriti , Marta Chinnici

Compartmental models of epidemics are widely used to forecast the effects of communicable diseases such as COVID-19 and to guide policy. Although it has long been known that such processes take place on social networks, the assumption of…

Physics and Society · Physics 2024-03-14 Samuel Johnson
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