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Artificial intelligence (AI) holds great promise for supporting clinical trials, from patient recruitment and endpoint assessment to treatment response prediction. However, deploying AI without safeguards poses significant risks,…

Machine Learning · Computer Science 2025-10-09 Yao Chen , David Ohlssen , Aimee Readie , Gregory Ligozio , Ruvie Martin , Thibaud Coroller

What shapes a consequential decision when human and artificial intelligence work on it together? The answer is becoming harder to see. A decision may look human-led after AI has set the frame, or appear automated while human judgment still…

Artificial Intelligence · Computer Science 2026-05-01 Alejandro R. Jadad

Safety frameworks represent a significant development in AI governance: they are the first type of publicly shared catastrophic risk management framework developed by major AI companies and focus specifically on AI scaling decisions. I…

Computers and Society · Computer Science 2024-10-02 Atoosa Kasirzadeh

The popularisation of applying AI in businesses poses significant challenges relating to ethical principles, governance, and legal compliance. Although businesses have embedded AI into their day-to-day processes, they lack a unified…

Artificial Intelligence · Computer Science 2024-12-09 Haocheng Lin

Agentic Artificial Intelligence (AI) represents a fundamental shift in the design of intelligent systems, characterized by interconnected components that collectively enable autonomous perception, reasoning, planning, action, and learning.…

Artificial intelligence (AI) holds great promise to empower us with knowledge and augment our effectiveness. We can -- and must -- ensure that we keep humans safe and in control, particularly with regard to government and public sector…

Artificial Intelligence · Computer Science 2019-10-09 Carol J. Smith

AI agents -- systems that combine foundation models with reasoning, planning, memory, and tool use -- are rapidly becoming a practical interface between natural-language intent and real-world computation. This survey synthesizes the…

Artificial Intelligence · Computer Science 2026-01-06 Bin Xu

The more AI agents are deployed in scenarios with possibly unexpected situations, the more they need to be flexible, adaptive, and creative in achieving the goal we have given them. Thus, a certain level of freedom to choose the best path…

Artificial Intelligence · Computer Science 2018-12-11 Francesca Rossi , Nicholas Mattei

Solutions relying on artificial intelligence are devised to predict data patterns and answer questions that are clearly defined, involve an enumerable set of solutions, clear rules, and inherently binary decision mechanisms. Yet, as they…

Computers and Society · Computer Science 2020-10-30 Niya Stoimenova , Rebecca Price

Human error remains a dominant risk driver in safety-critical sectors such as nuclear power, aviation, and healthcare, where seemingly minor mistakes can cascade into catastrophic outcomes. Although decades of research have produced a rich…

Human-Computer Interaction · Computer Science 2025-07-02 Xingyu Xiao , Hongxu Zhu , Jingang Liang , Jiejuan Tong , Haitao Wang

Public sector agencies are rapidly deploying AI systems to augment or automate critical decisions in real-world contexts like child welfare, criminal justice, and public health. A growing body of work documents how these AI systems often…

Human-Computer Interaction · Computer Science 2024-03-06 Anna Kawakami , Amanda Coston , Haiyi Zhu , Hoda Heidari , Kenneth Holstein

Large language models increasingly function as epistemic agents -- entities that can 1) autonomously pursue epistemic goals and 2) actively shape our shared knowledge environment. They curate the information we receive, often supplanting…

Artificial Intelligence · Computer Science 2026-03-24 Nahema Marchal , Stephanie Chan , Matija Franklin , Manon Revel , Geoff Keeling , Roberta Fischli , Bilva Chandra , Iason Gabriel

As AI systems demonstrate increasingly strong predictive performance, their adoption has grown in numerous domains. However, in high-stakes domains such as criminal justice and healthcare, full automation is often not desirable due to…

Artificial Intelligence · Computer Science 2021-12-23 Vivian Lai , Chacha Chen , Q. Vera Liao , Alison Smith-Renner , Chenhao Tan

To realize the potential benefits and mitigate potential risks of AI, it is necessary to develop a framework of governance that conforms to ethics and fundamental human values. Although several organizations have issued guidelines and…

Computers and Society · Computer Science 2023-07-14 Hyesun Choung , Prabu David , John S. Seberger

Organizations of all sizes, across all industries and domains are leveraging artificial intelligence (AI) technologies to solve some of their biggest challenges around operations, customer experience, and much more. However, due to the…

Computers and Society · Computer Science 2022-11-24 Navdeep Gill , Abhishek Mathur , Marcos V. Conde

Institutional decisions -- regulatory compliance, clinical triage, prior authorization appeal -- require a different AI architecture than general-purpose agents provide. Agent frameworks infer authority conversationally, reconstruct…

Artificial Intelligence · Computer Science 2026-04-14 Mamadou Seck

Lived experiences fundamentally shape how individuals interact with AI systems, influencing perceptions of safety, trust, and usability. While prior research has focused on developing techniques to emulate human preferences, and proposed…

Computers and Society · Computer Science 2025-08-12 Sanjana Gautam , Mohit Chandra , Ankolika De , Tatiana Chakravorti , Girik Malik , Munmun De Choudhury

In AI-assisted decision-making, it is crucial but challenging for humans to appropriately rely on AI, especially in high-stakes domains such as finance and healthcare. This paper addresses this problem from a human-centered perspective by…

Human-Computer Interaction · Computer Science 2025-02-21 Takehiro Takayanagi , Ryuji Hashimoto , Chung-Chi Chen , Kiyoshi Izumi

In the ever-expanding landscape of Artificial Intelligence (AI), where innovation thrives and new products and services are continuously being delivered, ensuring that AI systems are designed and developed responsibly throughout their…

Software Engineering · Computer Science 2024-05-10 Maria Teresa Baldassarre , Domenico Gigante , Marcos Kalinowski , Azzurra Ragone

Explanations for artificial intelligence (AI) systems are intended to support the people who are impacted by AI systems in high-stakes decision-making environments, such as doctors, patients, teachers, students, housing applicants, and many…

Human-Computer Interaction · Computer Science 2025-04-16 Gennie Mansi , Naveena Karusala , Mark Riedl
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