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Latent tree analysis seeks to model the correlations among a set of random variables using a tree of latent variables. It was proposed as an improvement to latent class analysis --- a method widely used in social sciences and medicine to…

Machine Learning · Computer Science 2016-10-04 Nevin L. Zhang , Leonard K. M. Poon

The reconstruction of transmission trees for epidemics from genetic data has been the subject of some recent interest. It has been demonstrated that the transmission tree structure can be investigated by augmenting internal nodes of a…

Populations and Evolution · Quantitative Biology 2016-01-07 Matthew Hall , Andrew Rambaut

Phylogenies (ancestry trees) depict the evolutionary history of an evolving population. In evolutionary computing, a phylogeny can reveal how an evolutionary algorithm steers a population through a search space, illuminating the…

Neural and Evolutionary Computing · Computer Science 2023-06-08 Alexander Lalejini , Matthew Andres Moreno , Jose Guadalupe Hernandez , Emily Dolson

Phylogenetics, the inference of evolutionary trees from molecular sequence data such as DNA, is an enterprise that yields valuable evolutionary understanding of many biological systems. Bayesian phylogenetic algorithms, which approximate a…

Populations and Evolution · Quantitative Biology 2016-10-27 Vu Dinh , Aaron E. Darling , Frederick A. Matsen

Inferential summaries of tree estimates are useful in the setting of evolutionary biology, where phylogenetic trees have been built from DNA data since the 1960's. In bioinformatics, psychometrics and data mining, hierarchical clustering…

Applications · Statistics 2010-06-08 John Chakerian , Susan Holmes

Phylogenetic networks are an extension of phylogenetic trees which are used to represent evolutionary histories in which reticulation events (such as recombination and hybridization) have occurred. A central question for such networks is…

Populations and Evolution · Quantitative Biology 2018-03-28 Andrew Francis , Vincent Moulton

Phylogenetic mixtures model the inhomogeneous molecular evolution commonly observed in data. The performance of phylogenetic reconstruction methods where the underlying data is generated by a mixture model has stimulated considerable recent…

Populations and Evolution · Quantitative Biology 2007-06-30 Frederick A. Matsen , Mike Steel

Phylogenetic network is an evolutionary model that uses a rooted directed acyclic graph (instead of a tree) to model an evolutionary history of species in which reticulate events (e.g., hybrid speciation or horizontal gene transfer)…

Populations and Evolution · Quantitative Biology 2023-12-01 Yufeng Wu , Louxin Zhang

Selective inference is considered for testing trees and edges in phylogenetic tree selection from molecular sequences. This improves the previously proposed approximately unbiased test by adjusting the selection bias when testing many trees…

Applications · Statistics 2019-05-27 Hidetoshi Shimodaira , Yoshikazu Terada

Evolutionary relationships between species are usually inferred through phylogenetic analysis, which provides phylogenetic trees computed from allelic profiles built by sequencing specific regions of the sequences and abstracting them to…

Data Structures and Algorithms · Computer Science 2021-01-01 Luana Silva

Tree-based networks are a class of phylogenetic networks that attempt to formally capture what is meant by "tree-like" evolution. A given non-tree-based phylogenetic network, however, might appear to be very close to being tree-based, or…

Populations and Evolution · Quantitative Biology 2020-01-17 Mareike Fischer , Andrew Francis

Rooted phylogenetic networks are used to describe evolutionary histories that contain non-treelike evolutionary events such as hybridization and horizontal gene transfer. In some cases, such histories can be described by a phylogenetic…

Populations and Evolution · Quantitative Biology 2016-10-03 Laura Jetten , Leo van Iersel

Identifying undocumented or potential future interactions among species is a challenge facing modern ecologists. Recent link prediction methods rely on trait data, however large species interaction databases are typically sparse and…

Applications · Statistics 2019-09-23 Mohamad Elmasri , Maxwell J. Farrell , T. Jonathan Davies , David A. Stephens

Phylogenies are commonly used to represent the evolutionary relationships between species, and often these phylogenies are equipped with edge lengths that indicate degrees of evolutionary difference. Given such a phylogeny, a popular…

Populations and Evolution · Quantitative Biology 2025-02-12 Martin Frohn , Kerry Manson

In biological experiments researchers often have information in the form of a graph that supplements observed numerical data. Incorporating the knowledge contained in these graphs into an analysis of the numerical data is an important and…

Applications · Statistics 2012-02-28 Elizabeth Purdom

Phylogenetic trees describe the relationships between species in the evolutionary process, and provide information about the rates of diversification. To understand the mechanisms behind macroevolution, we consider a class of multitype…

Populations and Evolution · Quantitative Biology 2024-10-07 Mingqi He , Sophie Hautphenne , Yao-ban Chan

The way to infer well-supported phylogenetic trees that precisely reflect the evolutionary process is a challenging task that completely depends on the way the related core genes have been found. In previous computational biology studies,…

Phylogenetic analyses which include fossils or molecular sequences that are sampled through time require models that allow one sample to be a direct ancestor of another sample. As previously available phylogenetic inference tools assume…

Populations and Evolution · Quantitative Biology 2014-12-08 Alexandra Gavryushkina , David Welch , Tanja Stadler , Alexei Drummond

Phylogenetic comparative methods (PCMs) are widely used to study trait evolution. However, many evolutionary histories involve reticulate evolutionary scenarios, such as hybridization, that violate core assumptions of these methods. In this…

Populations and Evolution · Quantitative Biology 2026-03-30 Lydia Morley , Emma Lehmberg , Sungsik Kong

Construction of phylogenetic trees and networks for extant species from their characters represents one of the key problems in phylogenomics. While solution to this problem is not always uniquely defined and there exist multiple methods for…

Populations and Evolution · Quantitative Biology 2016-08-10 Nikita Alexeev , Max A. Alekseyev