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As we gain access to a greater depth and range of health-related information about individuals, three questions arise: (1) Can we build better models to predict individual-level risk of ill health? (2) How much data do we need to…

Machine Learning · Statistics 2021-04-27 Mark Green

We propose a new modeling and estimation approach to select the optimal treatment regime from different options through constructing a robust estimating equation. The method is protected against misspecification of the propensity score…

Methodology · Statistics 2022-11-15 Trinetri Ghosh , Yanyuan Ma , Wensheng Zhu , Yuanjia Wang

The biggest Breast cancer is increasingly a major factor in female fatalities, overtaking heart disease. While genetic factors are important in the growth of breast cancer, new research indicates that environmental factors also play a…

Machine Learning · Computer Science 2023-09-27 Muhammad Shoaib Farooq , Mehreen Ilyas

Forecasts of mortality provide vital information about future populations, with implications for pension and health-care policy as well as for decisions made by private companies about life insurance and annuity pricing. Stochastic…

Applications · Statistics 2018-06-21 Jason Hilton , Erengul Dodd , Jonathan J. Forster , Peter W. F. Smith

Type 2 diabetes mellitus represents a prevalent and widespread global health concern, necessitating a comprehensive assessment of its risk factors. This study aimed towards learning whether there is any differential impact of age,…

Evidence from animal models and epidemiological studies has linked prenatal alcohol exposure (PAE) to a broad range of long-term cognitive and behavioral deficits. However, there is virtually no information in the scientific literature…

Physical growth traits can be naturally represented by continuous functions. In a large dataset of infancy growth patterns, we develop a practical approach to infer statistical associations between growth-trajectories and IQ performance in…

During the perinatal period, psychosocial health risks, including depression and intimate partner violence, are associated with serious adverse health outcomes for parents and children. To appropriately intervene, healthcare professionals…

Computation and Language · Computer Science 2020-05-01 Kristen C. Allen , Alex Davis , Tamar Krishnamurti

Premature birth and various pre- and peri-natal stresses can lead to a variety of brain lesions and have clearly been identified as major risk factors for neurodevelopmental disorders, with variable but multiple consequences that can…

Neurons and Cognition · Quantitative Biology 2025-05-01 Jessica Dubois , Lucie Hertz-Pannier , Sara Neumane

Fertility choices are linked to the different preferences and constraints of individuals and couples, and vary importantly by socio-economic status, as well by cultural and institutional context. The meaning of childbearing and…

Computers and Society · Computer Science 2017-03-14 Jussi Ojala , Emilio Zagheni , Francesco C. Billari , Ingmar Weber

Fertility differentials by urban-rural residence and nativity of women in Australia significantly impact population composition at sub-national levels. We aim to provide consistent fertility forecasts for Australian women characterized by…

Applications · Statistics 2024-10-25 Yang Yang , Han Lin Shang , James Raymer

BACKGROUND There is an increasing demand for high quality subnational estimates of under-five mortality. In low and middle income countries, where the burden of under-five mortality is concentrated, vital registration is often lacking and…

Methodology · Statistics 2020-11-17 Katie Wilson , Jon Wakefield

Obesity affects a rising percentage of the children and adolescent population, contributing to decreased quality of life and increased risk for comorbidities. Although the major causes of obesity are known, the obesogenic behaviors manifest…

Computers and Society · Computer Science 2021-05-21 Ioannis Sarafis , Christos Diou , Vasileios Papapanagiotou , Leonidas Alagialoglou , Anastasios Delopoulos

Mathematicians have always been attracted to the field of genetics. I am especially interested in the mathematical aspects of research on homosexuality. Certain studies show that male homosexuality may have a genetic component that is…

Other Quantitative Biology · Quantitative Biology 2017-11-28 Tanya Khovanova

Prenatal psychological stress affects 15-25% of pregnancies and increases risks of preterm birth, low birth weight, and adverse neurodevelopmental outcomes. Current screening relies on subjective questionnaires (PSS-10), limiting continuous…

Quantitative Methods · Quantitative Biology 2026-04-28 Martin G. Frasch , Marlene J. E. Mayer , Clara Becker , Peter Zimmermann , Camilla Zelgert , Marta C. Antonelli , Silvia M. Lobmaier

Adverse conditions in early life can have consequential impacts on individuals' health in older age. In one of the first papers on this topic, Barker and Osmond 1986 show a strong positive relationship between infant mortality rates in the…

General Economics · Economics 2025-03-05 Samuel Baker , Pietro Biroli , Hans van Kippersluis , Stephanie von Hinke

Randomized controlled clinical trials provide the gold standard for evidence generation in relation to the efficacy of a new treatment in medical research. Relevant information from previous studies may be desirable to incorporate in the…

Methodology · Statistics 2024-05-29 Lou E. Whitehead , James M. S. Wason , Oliver Sailer , Haiyan Zheng

Fetal health is a critical concern during pregnancy as it can impact the well-being of both the mother and the baby. Regular monitoring and timely interventions are necessary to ensure the best possible outcomes. While there are various…

Machine Learning · Computer Science 2023-05-30 Md. Simul Hasan Talukder , Sharmin Akter

After birth setting up an effective immune system is a major challenge for all living organisms. In this paper we show that this process can be explored by using the age-specific infant death rate as a kind of sensor. This is made possible…

Medical Physics · Physics 2016-10-10 Peter Richmond , Bertrand M. Roehner

More than one-third of the adult population in the United States is obese. Obesity has been linked to factors such as, genetics, diet, physical activity and the environment. However, evidence indicating associations between the built…

Computers and Society · Computer Science 2018-09-11 Adyasha Maharana , Elaine O. Nsoesie