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Noninvasive optical imaging modalities can probe patient's tissue in 3D and over time generate gigabytes of clinically relevant data per sample. There is a need for AI models to analyze this data and assist clinical workflow. The lack of…

Modern medical records include a vast amount of multimodal free text clinical data and imaging data from radiology, cardiology, and digital pathology. Fully mining such big data requires multitasking; otherwise, occult but important aspects…

Image and Video Processing · Electrical Eng. & Systems 2024-04-25 Chuang Niu , Qing Lyu , Christopher D. Carothers , Parisa Kaviani , Josh Tan , Pingkun Yan , Mannudeep K. Kalra , Christopher T. Whitlow , Ge Wang

In the past five years, the use of generative and foundational AI systems has greatly improved the decoding of brain activity. Visual perception, in particular, can now be decoded from functional Magnetic Resonance Imaging (fMRI) with…

Image and Video Processing · Electrical Eng. & Systems 2024-03-15 Yohann Benchetrit , Hubert Banville , Jean-Rémi King

Foundation models (FMs) are driving a prominent shift in biomedical imaging from task-specific models to unified backbone models for diverse tasks. This opens an avenue to integrate imaging, pathology, clinical records, and genomics data…

Quantitative Methods · Quantitative Biology 2026-04-23 Amgad Muneer , Kai Zhang , Ibraheem Hamdi , Rizwan Qureshi , Muhammad Waqas , Shereen Fouad , Hazrat Ali , Syed Muhammad Anwar , Jia Wu

Multimodal MRI provides complementary and clinically relevant information to probe tissue condition and to characterize various diseases. However, it is often difficult to acquire sufficiently many modalities from the same subject due to…

Image and Video Processing · Electrical Eng. & Systems 2021-06-08 Xiaofeng Liu , Fangxu Xing , Georges El Fakhri , Jonghye Woo

Recent advances in large-scale pre-trained Electroencephalogram (EEG) models have shown great promise, driving progress in Brain-Computer Interfaces (BCIs) and healthcare applications. However, despite their success, many existing…

Machine Learning · Computer Science 2025-10-07 Konstantinos Barmpas , Na Lee , Yannis Panagakis , Dimitrios A. Adamos , Nikolaos Laskaris , Stefanos Zafeiriou

The burgeoning field of brain health research increasingly leverages artificial intelligence (AI) to interpret and analyze neurological data. This study introduces a novel approach towards the creation of medical foundation models by…

Image and Video Processing · Electrical Eng. & Systems 2024-11-08 Joseph Cox , Peng Liu , Skylar E. Stolte , Yunchao Yang , Kang Liu , Kyle B. See , Huiwen Ju , Ruogu Fang

Brain Foundation Models (BFMs) are transforming neuroscience by enabling scalable and transferable learning from neural signals, advancing both clinical diagnostics and cutting-edge neuroscience exploration. Their emergence is powered by…

Machine Learning · Computer Science 2026-02-13 Fanqi Shen , Enhong Yang , Jiahe Li , Junru Hong , Xiaoran Pan , Zhizhang Yuan , Meng Li , Yang Yang

Computed tomography (CT) and clinical numeric data are essential modalities for cancer evaluation, but building large-scale multimodal training datasets for developing medical foundation models remains challenging due to the structural…

Computer Vision and Pattern Recognition · Computer Science 2025-01-24 Daeun Jung , Jaehyeok Jang , Sooyoung Jang , Yu Rang Park

Sleep is a complex physiological process evaluated through various modalities recording electrical brain, cardiac, and respiratory activities. We curate a large polysomnography dataset from over 14,000 participants comprising over 100,000…

Machine Learning · Computer Science 2024-05-29 Rahul Thapa , Bryan He , Magnus Ruud Kjaer , Hyatt Moore , Gauri Ganjoo , Emmanuel Mignot , James Zou

Foundational models, pretrained on a large scale, have demonstrated substantial success across non-medical domains. However, training these models typically requires large, comprehensive datasets, which contrasts with the smaller and more…

Computer Vision and Pattern Recognition · Computer Science 2023-11-17 Raphael Schäfer , Till Nicke , Henning Höfener , Annkristin Lange , Dorit Merhof , Friedrich Feuerhake , Volkmar Schulz , Johannes Lotz , Fabian Kiessling

Harnessing the power of deep neural networks in the medical imaging domain is challenging due to the difficulties in acquiring large annotated datasets, especially for rare diseases, which involve high costs, time, and effort for…

Image and Video Processing · Electrical Eng. & Systems 2023-08-22 Md Mahfuzur Rahman Siddiquee , Jay Shah , Teresa Wu , Catherine Chong , Todd J. Schwedt , Gina Dumkrieger , Simona Nikolova , Baoxin Li

Existing foundation models (FMs) in the medical domain often require extensive fine-tuning or rely on training resource-intensive decoders, while many existing encoders are pretrained with objectives biased toward specific tasks. This…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Tim Veenboer , George Yiasemis , Eric Marcus , Vivien Van Veldhuizen , Cees G. M. Snoek , Jonas Teuwen , Kevin B. W. Groot Lipman

Current deep learning models are mostly task specific and lack a user-friendly interface to operate. We present Meta-EyeFM, a multi-function foundation model that integrates a large language model (LLM) with vision foundation models (VFMs)…

Establishing voxelwise semantic correspondence across distinct imaging modalities is a foundational yet formidable computer vision task. Current multi-modality registration techniques maximize hand-crafted inter-domain similarity functions,…

Computer Vision and Pattern Recognition · Computer Science 2022-06-28 Neel Dey , Jo Schlemper , Seyed Sadegh Mohseni Salehi , Bo Zhou , Guido Gerig , Michal Sofka

Multimodal medical image fusion (MMIF) aims to integrate images from different modalities to produce a comprehensive image that enhances medical diagnosis by accurately depicting organ structures, tissue textures, and metabolic information.…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Tao Luo , Weihua Xu

In MRI, images of the same contrast (e.g., T$_1$) from the same subject can exhibit noticeable differences when acquired using different hardware, sequences, or scan parameters. These differences in images create a domain gap that needs to…

Image and Video Processing · Electrical Eng. & Systems 2023-08-17 Hwihun Jeong , Heejoon Byun , Dong Un Kang , Jongho Lee

Synthesizing missing modalities in multi-modal magnetic resonance imaging (MRI) is vital for ensuring diagnostic completeness, particularly when full acquisitions are infeasible due to time constraints, motion artifacts, and patient…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Yue Zhang , Zhizheng Zhuo , Siyao Xu , Shan Lv , Zhaoxi Liu , Jun Qiu , Qiuli Wang , Yaou Liu , S. Kevin Zhou

Magnetic resonance imaging (MRI) image segmentation is crucial in diagnosing and treating many diseases, such as brain tumors. Existing MRI image segmentation methods mainly fall into a centralized multimodal paradigm, which is inapplicable…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Guyue Hu , Siyuan Song , Jingpeng Sun , Zhe Jin , Chenglong Li , Jin Tang

Brain imaging plays a crucial role in the diagnosis and treatment of various neurological disorders, providing valuable insights into the structure and function of the brain. Techniques such as magnetic resonance imaging (MRI) and computed…

Image and Video Processing · Electrical Eng. & Systems 2025-01-23 Fatima Haimour , Rizik Al-Sayyed , Waleed Mahafza , Omar S. Al-Kadi
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