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We introduce PRISM (Predictive Reasoning in Sequential Medicine), a transformer-based architecture designed to model the sequential progression of clinical decision-making processes. Unlike traditional approaches that rely on isolated…

Computation and Language · Computer Science 2025-06-16 Lionel Levine , John Santerre , Alex S. Young , T. Barry Levine , Francis Campion , Majid Sarrafzadeh

Development and operation of commercially viable fusion energy reactors such as tokamaks require accurate predictions of plasma dynamics from sparse, noisy, and incomplete sensors readings. The complexity of the underlying physics and the…

Virtual screening of small molecules against protein targets can accelerate drug discovery and development by predicting drug-target interactions (DTIs). However, structure-based methods like molecular docking are too slow to allow for…

We propose PRISM-Loc - a lightweight and robust approach for localization in large outdoor environments that combines a compact topological representation with a novel scan-matching and curb-detection module operating on raw LiDAR scans.…

Saskatchewan Torus-Modified (STOR-M) is a small tokamak, well known for various fusion related basic experimental studies such as edge turbulent heating, different instabilities, AC (alternating current) tokamak operation, Ohmic H-mode…

Plasma Physics · Physics 2022-06-20 Masaru Nakajima , Debjyoti Basu , A. V. Melnikov , David McColl , Chijin Xiao

Simulation of atomic resolution image formation in scanning transmission electron microscopy can require significant computation times using traditional methods. A recently developed method, termed plane-wave reciprocal-space interpolated…

Computational Physics · Physics 2017-07-07 Alan Pryor , Colin Ophus , Jianwei Miao

Safeguarding vision-language models (VLMs) is a critical challenge, as existing methods often suffer from over-defense, which harms utility, or rely on shallow alignment, failing to detect complex threats that require deep reasoning. To…

Cryptography and Security · Computer Science 2026-04-03 Nanxi Li , Zhengyue Zhao , G. Edward Suh , Marco Pavone , Chaowei Xiao

There is an increasing need to model plasma interaction with complex engineered surfaces, notably to verify that power deposition rates are acceptable. The SMARDDA algorithm has been developed to meet this requirement, with particular…

Plasma Physics · Physics 2015-10-28 Wayne Arter , Elizabeth Surrey , Damian. B. King

With the rapid progress of large language models (LLMs), financial information retrieval has become a critical industrial application. Extracting task-relevant information from lengthy financial filings is essential for both operational and…

Artificial Intelligence · Computer Science 2026-04-07 Chun Chet Ng , Jia Yu Lim , Wei Zeng Low

In this paper, we propose Precision-Informed Semantic Modeling (PRISM), a structured topic modeling framework combining the benefits of rich representations captured by LLMs with the low cost and interpretability of latent semantic…

Machine Learning · Computer Science 2026-04-06 Connor Douglas , Utkucan Balci , Joseph Aylett-Bullock

Deploying large language model (LLM)-driven conversational agents in enterprise settings requires prompts that are simultaneously correct at launch and resilient to the non-deterministic behavioral drift that characterizes production LLM…

Artificial Intelligence · Computer Science 2026-05-18 Keshava Chaitanya , Jahnavi Gundakaram

Crystal structures are characterised by repeating atomic patterns within unit cells across three-dimensional space, posing unique challenges for graph-based representation learning. Current methods often overlook essential periodic boundary…

In this paper we introduce a tool called Principal Image Sections Mapping - PRISM, dedicated for PyTorch, but can be easily ported to other deep learning frameworks. Presented software relies on Principal Component Analysis to visualize the…

Computer Vision and Pattern Recognition · Computer Science 2021-01-28 Tomasz Szandala

Recent advances in photonic inverse design have demonstrated the ability to automatically synthesize compact, high-performance photonic components that surpass conventional, hand-designed structures, offering a promising path toward…

Optics · Physics 2026-02-18 Hongjian Zhou , Haoyu Yang , Nicholas Gangi , Tianle Xu , Rena Huang , Jiaqi Gu

Our goal in this dissertation is to provide tools, programming models, and system support for PIM architectures (with a focus on DRAM-based solutions), to ease the adoption of PIM in current and future systems. To this end, we make at least…

Hardware Architecture · Computer Science 2025-08-28 Geraldo F. Oliveira

Designing protein sequences that fold into a target 3-D structure, termed as the inverse folding problem, is central to protein engineering. However, it remains challenging due to the vast sequence space and the importance of local…

Quantitative Methods · Quantitative Biology 2026-03-17 Sazan Mahbub , Souvik Kundu , Eric P. Xing

Multivariate time series classification supports applications from wearable sensing to biomedical monitoring and demands models that can capture both short-term patterns and multi-scale temporal dependencies. Despite recent advances,…

Machine Learning · Computer Science 2026-04-07 Federico Zucchi , Thomas Lampert

Several visualization schemes have been developed for imaging materials at the atomic level through atom probe tomography. The main shortcoming of these tools is their inability to parallel process data using multi-core computing units to…

Materials Science · Physics 2012-02-07 Hari Dahal , Michael Stukowski , Matthias J. Graf , Alexander V. Balatsky , Krishna Rajan

Simultaneous Localization and Mapping (SLAM) is a key tool for monitoring construction sites, where aligning the evolving as-built state with the as-planned design enables early error detection and reduces costly rework. LiDAR-based SLAM…

Distributed as an open source library since 2013, RTAB-Map started as an appearance-based loop closure detection approach with memory management to deal with large-scale and long-term online operation. It then grew to implement Simultaneous…

Robotics · Computer Science 2024-03-12 Mathieu Labbé , François Michaud