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200 papers

Microbial networks, representing microbes as nodes and their interactions as edges, are crucial for understanding community dynamics in various environments. Analyzing microbiome networks is crucial for identifying keystone taxa that play…

Molecular Networks · Quantitative Biology 2025-07-15 Qiyao Yang , Rosa Aghdam , Reed Nelson , Claudia Solís-Lemus

Large-scale perturbations in the microbiome constitution are strongly correlated, whether as a driver or a consequence, with the health and functioning of human physiology. However, understanding the difference in the microbiome profiles of…

Quantitative Methods · Quantitative Biology 2022-09-08 Kateryna Melnyk , Kuba Weimann , Tim O. F. Conrad

We propose a general parametrizable model to capture the dynamic interaction among bacteria in the formation of micro-colonies. micro-colonies represent the first social step towards the formation of structured multicellular communities…

Populations and Evolution · Quantitative Biology 2014-10-30 Luca Canzian , Kun Zhao , Gerard C. L. Wong , Mihaela van der Schaar

The human body consists of microbiomes associated with the development and prevention of several diseases. These microbial organisms form several complex interactions that are informative to the scientific community for explaining disease…

Methodology · Statistics 2024-04-16 Tejasv Bedi , Bencong Zhu , Michael L. Neugent , Kevin C. Lutz , Nicole J. De Nisco , Qiwei Li

The rise in the availability of bacterial genomes defines a need for synthesis: abstracting from individual taxa, to see larger patterns of bacterial lifestyles across systems. A key concept for such synthesis in ecology is the niche, the…

Populations and Evolution · Quantitative Biology 2020-11-03 Ashkaan K Fahimipour , Thilo Gross

Modeling environmental ecosystems is essential for effective resource management, sustainable development, and understanding complex ecological processes. However, traditional methods frequently struggle with the inherent complexity,…

Machine Learning · Computer Science 2025-03-06 Runlong Yu , Shengyu Chen , Yiqun Xie , Xiaowei Jia

Feature interaction selection is a fundamental problem in commercial recommender systems. Most approaches equally enumerate all features and interactions by the same pre-defined operation under expert guidance. Their recommendation is…

Artificial Intelligence · Computer Science 2024-05-30 Runlong Yu , Qixiang Shao , Qi Liu , Huan Liu , Enhong Chen

Microbial communities are widely studied using high-throughput sequencing techniques, such as 16S rRNA gene sequencing. These techniques have attracted biologists as they offer powerful tools to explore microbial communities and investigate…

Applications · Statistics 2021-04-06 Elham Bayat Mokhtari , Benjamin Ridenhour

Numerous cellular functions rely on protein$\unicode{x2013}$protein interactions. Efforts to comprehensively characterize them remain challenged however by the diversity of molecular recognition mechanisms employed within the proteome. Deep…

Biomolecules · Quantitative Biology 2023-12-08 Julia R. Rogers , Gergő Nikolényi , Mohammed AlQuraishi

Molecular ecology uses molecular genetic data to answer traditional ecological questions in biogeography and biodiversity among others. Several ecological principles, such as the niche hypothesis and the competitive exclusions, are based on…

A system-level framework of complex microbe-microbe and host-microbe chemical cross-talk would help elucidate the role of our gut microbiota in health and disease. Here we report a literature-curated interspecies network of the human gut…

Molecular Networks · Quantitative Biology 2017-06-07 Jaeyun Sung , Seunghyeon Kim , Josephine Jill T. Cabatbat , Sungho Jang , Yong-Su Jin , Gyoo Yeol Jung , Nicholas Chia , Pan-Jun Kim

Lately, experimental research on microbial symbioses based on nutrient exchange and interdependence has yielded a number of interesting findings, however an in-depth mathematical description of the exact underlying dynamics of such…

Populations and Evolution · Quantitative Biology 2019-08-08 Matthias M. Fischer

Experimental studies of microbial communities routinely reveal that they have multiple stable states. While each of these states is generally resilient, certain perturbations such as antibiotics, probiotics and diet shifts, result in…

Populations and Evolution · Quantitative Biology 2019-02-15 Akshit Goyal , Veronika Dubinkina , Sergei Maslov

A central and long-standing issue in evolutionary theory is the origin of the biological variation upon which natural selection acts1. Some hypotheses suggest that evolutionary change represents an adaptation to the surrounding environment…

Statistical Mechanics · Physics 2007-05-23 J. Podani , Z. N. Oltvai , H. Jeong , B. Tombor , A. -L. Barabasi , E. Szathmary

Growing anthropogenic pressures have increased the need for robust predictive models. Meeting this demand requires approaches that can handle bigger data to yield forecasts that capture the variability and underlying uncertainty of…

Quantitative Methods · Quantitative Biology 2024-08-06 EM Wolkovich , T Jonathan Davies , William D Pearse , Michael Betancourt

Understanding predator-prey relationships among insects is a challenging task in the domain of insect-colony research. This is due to several factors involved, such as determining whether a particular behavior is the result of a…

Artificial Intelligence · Computer Science 2009-12-15 Karthik Narayanaswami

Dormancy is an essential strategy for microorganisms to cope with environmental stress. However, global ecosystem models typically ignore microbial dormancy, resulting in major model uncertainties. To facilitate the consideration of…

Quantitative Methods · Quantitative Biology 2014-02-20 Gangsheng Wang , Melanie A. Mayes , Lianhong Gu , Christopher W. Schadt

Microbes providing public goods are widespread in nature despite running the risk of being exploited by free-riders. However, the precise ecological factors supporting cooperation are still puzzling. Following recent experiments, we…

Populations and Evolution · Quantitative Biology 2012-03-28 Jonas Cremer , Anna Melbinger , Erwin Frey

Microalgae, vital for ecological balance and economic sectors, present challenges in detection due to their diverse sizes and conditions. This paper summarizes the second "Vision Meets Algae" (VisAlgae 2023) Challenge, aiming to enhance…

Previous work has shown that species interacting in an ecosystem and actors transacting in an economic context may have notable similarities in behavior. However, the specific mechanism that may underlie similarities in nature and human…

Physics and Society · Physics 2011-10-04 Serguei Saavedra , Felix Reed-Tsochas , Brian Uzzi