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EEG foundation models achieve state-of-the-art clinical performance, yet the internal computations driving their predictions remain opaque: a barrier to clinical trust. We apply TopK Sparse Autoencoders (SAEs) across three architecturally…

Deep learning models have shown promise in EEG-based outcome prediction for comatose patients after cardiac arrest, but their reliability is often compromised by subtle forms of data leakage. In particular, when long EEG recordings are…

Machine Learning · Computer Science 2026-03-30 Yixin Zhou , Zhixiang Liu , Vladimir I. Zadorozhny , Jonathan Elmer

Deep Learning has impacted various fields especially in bio-medical applications. Deep learning algorithms work well with both structured and unstructured data. Especially, convolutional neural network work well with signal-based data like…

Signal Processing · Electrical Eng. & Systems 2022-01-11 Shivaditya Shivganesh

Electroencephalography foundation models (EEG-FMs) have advanced brain signal analysis, but the lack of standardized evaluation benchmarks impedes model comparison and scientific progress. Current evaluations rely on inconsistent protocols…

Signal Processing · Electrical Eng. & Systems 2026-02-16 Wei Xiong , Jiangtong Li , Jie Li , Kun Zhu , Changjun Jiang

In recent years, the field of electroencephalography (EEG) analysis has witnessed remarkable advancements, driven by the integration of machine learning and artificial intelligence. This survey aims to encapsulate the latest developments,…

Signal Processing · Electrical Eng. & Systems 2025-01-09 Pengfei Wang , Huanran Zheng , Silong Dai , Yiqiao Wang , Xiaotian Gu , Yuanbin Wu , Xiaoling Wang

The HeartBert model is introduced with three primary objectives: reducing the need for labeled data, minimizing computational resources, and simultaneously improving performance in machine learning systems that analyze Electrocardiogram…

Signal Processing · Electrical Eng. & Systems 2026-04-29 Saedeh Tahery , Fatemeh Hamid Akhlaghi , Termeh Amirsoleimani

Deep learning models have shown high accuracy in classifying electrocardiograms (ECGs), but their black box nature hinders clinical adoption due to a lack of trust and interpretability. To address this, we propose a novel three-stage…

Machine Learning · Computer Science 2025-12-09 Jose Geraldo Fernandes , Luiz Facury de Souza , Pedro Robles Dutenhefner , Gisele L. Pappa , Wagner Meira

Although electrocardiograms (ECG) play a dominant role in cardiovascular diagnosis and treatment, their intrinsic data forms and representational patterns pose significant challenges for medical multimodal large language models (Med-MLLMs)…

Electroencephalography (EEG) is an invaluable tool in neuroscience, offering insights into brain activity with high temporal resolution. Recent advancements in machine learning and generative modeling have catalyzed the application of EEG…

Computer Vision and Pattern Recognition · Computer Science 2024-12-31 Yashvir Sabharwal , Balaji Rama

The field of cardiac electrophysiology tries to abstract, describe and finally model the electrical characteristics of a heartbeat. With recent advances in cardiac electrophysiology, models have become more powerful and descriptive as ever.…

Medical Physics · Physics 2022-12-16 Thomas Grandits , Simone Pezzuto , Gernot Plank

Data scarcity in the brain-computer interface field can be alleviated through the use of generative models, specifically diffusion models. While diffusion models have previously been successfully applied to electroencephalogram (EEG) data,…

Machine Learning · Computer Science 2024-11-05 Guido Klein , Pierre Guetschel , Gianluigi Silvestri , Michael Tangermann

Healthcare data now span EHRs, medical imaging, genomics, and wearable sensors, but most diagnostic models still process these modalities in isolation. This limits their ability to capture early, cross-modal disease signatures. This paper…

Machine Learning · Computer Science 2025-12-18 Md Talha Mohsin , Ismail Abdulrashid

Electrocardiography is a very common, non-invasive diagnostic procedure and its interpretation is increasingly supported by automatic interpretation algorithms. The progress in the field of automatic ECG interpretation has up to now been…

Machine Learning · Computer Science 2020-04-29 Nils Strodthoff , Patrick Wagner , Tobias Schaeffter , Wojciech Samek

Background: Artificial intelligence enabled electrocardiography (AI-ECG) has demonstrated the ability to detect diverse pathologies, but most existing models focus on single disease identification, neglecting comorbidities and future risk…

Signal Processing · Electrical Eng. & Systems 2026-01-19 Jun Li , Hongling Zhu , Yujie Xiao , Qinghao Zhao , Yalei Ke , Gongzheng Tang , Guangkun Nie , Deyun Zhang , Jin Li , Canqing Yu , Shenda Hong

Brain computer interface (BCI) research, as well as increasing portions of the field of neuroscience, have found success deploying large-scale artificial intelligence (AI) pre-training methods in conjunction with vast public repositories of…

Neurons and Cognition · Quantitative Biology 2025-06-03 Mattson Ogg , Rahul Hingorani , Diego Luna , Griffin W. Milsap , William G. Coon , Clara A. Scholl

Foundation models for EEG analysis are still in their infancy, limited by two key challenges: (1) variability across datasets caused by differences in recording devices and configurations, and (2) the low signal-to-noise ratio (SNR) of EEG,…

Machine Learning · Computer Science 2025-11-13 Navid Mohammadi Foumani , Soheila Ghane , Nam Nguyen , Mahsa Salehi , Geoffrey I. Webb , Geoffrey Mackellar

In this work we search for best practices in pre-processing of Electrocardiogram (ECG) signals in order to train better classifiers for the diagnosis of heart conditions. State of the art machine learning algorithms have achieved remarkable…

Signal Processing · Electrical Eng. & Systems 2025-05-16 Amir Salimi , Sunil Vasu Kalmady , Abram Hindle , Osmar Zaiane , Padma Kaul

Surface electromyogram (EMG) can be employed as an interface signal for various devices and software via pattern recognition. In EMG-based pattern recognition, the classifier should not only be accurate, but also output an appropriate…

Signal Processing · Electrical Eng. & Systems 2024-06-28 Akira Furui

Recent unified models such as GPT-5 have achieved encouraging progress on vision-language tasks. However, these unified models typically fail to correctly understand ECG signals and provide accurate medical diagnoses, nor can they correctly…

Computation and Language · Computer Science 2025-09-24 Jiarui Jin , Haoyu Wang , Xiang Lan , Jun Li , Gaofeng Cheng , Hongyan Li , Shenda Hong

In order to exploit representations of time-series signals, such as physiological signals, it is essential that these representations capture relevant information from the whole signal. In this work, we propose to use a Transformer-based…

Neurons and Cognition · Quantitative Biology 2022-06-06 Juan Vazquez-Rodriguez , Grégoire Lefebvre , Julien Cumin , James L. Crowley
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