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While pioneering deep learning methods have made great strides in analyzing electronic health record (EHR) data, they often struggle to fully capture the semantics of diverse medical codes from limited data. The integration of external…

Generative Artificial Intelligence (GenAI), specifically large language models (LLMs) like ChatGPT, has swiftly entered organizations without adequate governance, posing both opportunities and risks. Despite extensive debate on GenAI's…

Low back pain (LBP) is a leading cause of disability globally. Following the onset of LBP and subsequent treatment, adequate patient education is crucial for improving functionality and long-term outcomes. Despite advancements in patient…

The widespread adoption of electronic health records and digital healthcare data has created a demand for data-driven insights to enhance patient outcomes, diagnostics, and treatments. However, using real patient data presents privacy and…

Large language models (LLMs) hold promise for transforming healthcare, from streamlining administrative and clinical workflows to enriching patient engagement and advancing clinical decision-making. However, their successful integration…

Despite strong performance in medical question-answering, the clinical adoption of Large Language Models (LLMs) is critically hampered by their opaque 'black-box' reasoning, limiting clinician trust. This challenge is compounded by the…

his paper explores what kinds of questions are best served by the way generative AI (GenAI) using Large Language Models(LLMs) that aggregate and package knowledge, and when traditional curated web-sourced search results serve users better.…

Clinical decision-making is inherently complex, often influenced by cognitive biases, incomplete information, and case ambiguity. Large Language Models (LLMs) have shown promise as tools for supporting clinical decision-making, yet their…

The unstructured nature of clinical notes within electronic health records often conceals vital patient-related information, making it challenging to access or interpret. To uncover this hidden information, specialized Natural Language…

Generative AI (GenAI) has revolutionized content generation, offering transformative capabilities for improving language coherence, readability, and overall quality. This manuscript explores the application of qualitative, quantitative, and…

The rapid growth of medical knowledge and increasing complexity of clinical practice pose challenges. In this context, large language models (LLMs) have demonstrated value; however, inherent limitations remain. Retrieval-augmented…

Generative artificial intelligence (GenAI), based on large-language models (LLMs), such as ChatGPT, has taken organizations, academia, and the public by storm. In particular, impressive GenAI capabilities such as summarization of large text…

Artificial Intelligence (AI) has become essential in modern healthcare, with large language models (LLMs) offering promising advances in clinical decision-making. Traditional model-based approaches, including those leveraging in-context…

Frontier large language models (LLMs), such as GPT-5, Claude 4.5, Gemini 3, Llama 4, and DeepSeek-R1, represent a transformative class of AI tools capable of revolutionizing various aspects of healthcare by generating human-like responses…

The process of matching patients with suitable clinical trials is essential for advancing medical research and providing optimal care. However, current approaches face challenges such as data standardization, ethical considerations, and a…

The emergence of artificial general intelligence (AGI) is transforming radiation oncology. As prominent vanguards of AGI, large language models (LLMs) such as GPT-4 and PaLM 2 can process extensive texts and large vision models (LVMs) such…

Multimodal (MM) learning is emerging as a promising paradigm in biomedical artificial intelligence (AI) applications, integrating complementary modality, which highlight different aspects of patient health. The scarcity of large…

Generative artificial intelligence (AI) is rapidly transforming medical imaging by enabling capabilities such as data synthesis, image enhancement, modality translation, and spatiotemporal modeling. This review presents a comprehensive and…

The rapid advancement of Large Language Models (LLMs), reasoning models, and agentic AI approaches coincides with a growing global mental health crisis, where increasing demand has not translated into adequate access to professional…

Large language models (LLMs) are emerging as promising tools for mental health care, offering scalable support through their ability to generate human-like responses. However, the effectiveness of these models in clinical settings remains…