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Related papers: Improving Biomedical Knowledge Graph Quality: A Co…

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Biomedical knowledge graphs (KG) are heterogenous networks consisting of biological entities as nodes and relations between them as edges. These entities and relations are extracted from millions of research papers and unified in a single…

Artificial Intelligence · Computer Science 2022-11-11 Dattaraj J. Rao , Shraddha S. Mane , Mukta A. Paliwal

Biological systems are governed by structured molecular interactions, where pathways, regulatory circuits, and functional gene relationships shape cellular behavior and disease progression. Much of this knowledge is naturally represented as…

Machine Learning · Computer Science 2026-05-26 Yuwei Xue , Sakib Mostafa , James Zou , Joseph Liao , Maximilian Diehn , Ash A. Alizadeh , Lei Xing , Md. Tauhidul Islam

Background. In the last decades, several life science resources have structured data using the same framework and made these accessible using the same query language to facilitate interoperability. Knowledge graphs have seen increased…

Knowledge graphs (KGs) are useful for analyzing social structures, community dynamics, institutional memberships, and other complex relationships across domains from sociology to public health. While recent advances in large language models…

Computation and Language · Computer Science 2025-06-17 Erica Cai , Brendan O'Connor

Knowledge graphs and ontologies represent entities and their relationships in a structured way, having gained significance in the development of modern AI applications. Integrating these semantic resources with machine learning models often…

Machine Learning · Computer Science 2025-09-10 Hamid Ahmad , Heiko Paulheim , Rita T. Sousa

The large-scale development of large language models (LLMs) in medical contexts, such as diagnostic assistance and treatment recommendations, necessitates that these models possess accurate medical knowledge and deliver traceable…

Artificial Intelligence · Computer Science 2025-08-12 Qiyuan Li , Haijiang Liu , Caicai Guo , Chao Gao , Deyu Chen , Meng Wang , Feng Gao , Frank van Harmelen , Jinguang Gu

Knowledge Graphs have been one of the fundamental methods for integrating heterogeneous data sources. Integrating heterogeneous data sources is crucial, especially in the biomedical domain, where central data-driven tasks such as drug…

Machine Learning · Computer Science 2020-12-22 Islam Akef Ebeid , Majdi Hassan , Tingyi Wanyan , Jack Roper , Abhik Seal , Ying Ding

Knowledge Graphs (KG) and associated Knowledge Graph Embedding (KGE) models have recently begun to be explored in the context of drug discovery and have the potential to assist in key challenges such as target identification. In the drug…

Biomolecules · Quantitative Biology 2022-06-01 Stephen Bonner , Ian P Barrett , Cheng Ye , Rowan Swiers , Ola Engkvist , Charles Tapley Hoyt , William L Hamilton

Knowledge graphs (KGs) are important products of the semantic web, which are widely used in various application domains. Healthcare is one of such domains where KGs are intensively used, due to the high requirement for knowledge accuracy…

Artificial Intelligence · Computer Science 2025-07-31 Yuzhang Xie , Xu Han , Ran Xu , Xiao Hu , Jiaying Lu , Carl Yang

The intrinsic complexity of human biology presents ongoing challenges to scientific understanding. Researchers collaborate across disciplines to expand our knowledge of the biological interactions that define human life. AI methodologies…

Citation recommendation for research papers is a valuable task that can help researchers improve the quality of their work by suggesting relevant related work. Current approaches for this task rely primarily on the text of the papers and…

Digital Libraries · Computer Science 2021-06-11 Arthur Brack , Anett Hoppe , Ralph Ewerth

With the rapid development of biomedical software and hardware, a large amount of relational data interlinking genes, proteins, chemical components, drugs, diseases, and symptoms has been collected for modern biomedical research. Many…

Artificial Intelligence · Computer Science 2021-01-21 Yankai Chen , Yaozu Wu , Shicheng Ma , Irwin King

Sharing and reusing research artifacts, such as datasets, publications, or methods is a fundamental part of scientific activity, where heterogeneity of resources and metadata and the common practice of capturing information in unstructured…

In the medical domain, several disease treatment procedures have been documented properly as a set of instructions known as Clinical Practice Guidelines (CPGs). CPGs have been developed over the years on the basis of past treatments, and…

Information Retrieval · Computer Science 2023-08-08 Vasudhan Varma Kandula , Pushpak Bhattacharyya

Knowledge graphs (KGs) are powerful tools for modelling complex, multi-relational data and supporting hypothesis generation, particularly in applications like drug repurposing. However, for predictive methods to gain acceptance as credible…

Artificial Intelligence · Computer Science 2026-02-06 Susana Nunes , Samy Badreddine , Catia Pesquita

Biomedical knowledge graphs underwrite drug repurposing and clinical decision support, yet the upstream ontologies they depend on update on independent cycles that add millions of edges and deprecate hundreds of thousands more between…

Artificial Intelligence · Computer Science 2026-05-12 Yousef A. Radwan , Yao Li , Qing Qing , Ziqi Xu , Xingtong Yu , Jiaxing Huang , Renqiang Luo , Xikun Zhang

Personal Knowledge Graphs (PKGs) are introduced by the semantic web community as small-sized user-centric knowledge graphs (KGs). PKGs fill the gap of personalised representation of user data and interests on the top of big,…

Information Retrieval · Computer Science 2022-03-17 Eleni Ilkou

Knowledge Graphs (KGs) are a major asset for companies thanks to their great flexibility in data representation and their numerous applications, e.g., vocabulary sharing, Q/A or recommendation systems. To build a KG it is a common practice…

Artificial Intelligence · Computer Science 2024-07-22 Lucas Jarnac , Yoan Chabot , Miguel Couceiro

Knowledge Graphs (KGs) and their machine learning counterpart, Knowledge Graph Embedding Models (KGEMs), have seen ever-increasing use in a wide variety of academic and applied settings. In particular, KGEMs are typically applied to KGs to…

Machine Learning · Computer Science 2024-12-16 Jeffrey Sardina , John D. Kelleher , Declan O'Sullivan

Biomedical knowledge is fragmented across siloed databases -- Reactome for pathways, STRING for protein interactions, ClinicalTrials.gov for study registries, DrugBank for drug vocabularies, DGIdb for drug-gene interactions, SIDER for side…

Databases · Computer Science 2026-03-19 Madhulatha Mandarapu , Sandeep Kunkunuru