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High-throughput biological imaging is often constrained by a trade-off between acquisition speed and image quality. Fast imaging modalities, such as wide-field fluorescence microscopy, enable large-scale data acquisition but suffer from…

Image and Video Processing · Electrical Eng. & Systems 2026-04-20 Dominik Panek , Carina Rząca , Maksymilian Szczypior , Joanna Sorysz , Krzysztof Misztal , Zbigniew Baster , Zenon Rajfur

Improving the resolution of fluorescence microscopy beyond the diffraction limit can be achievedby acquiring and processing multiple images of the sample under different illumination conditions.One of the simplest techniques, Random…

We demonstrate a motion-free intensity diffraction tomography technique that enables direct inversion of 3D phase and absorption from intensity-only measurements for weakly scattering samples. We derive a novel linear forward model,…

Image and Video Processing · Electrical Eng. & Systems 2018-06-26 Ruilong Ling , Waleed Tahir , Hsing-Ying Lin , Hakho Lee , Lei Tian

This paper provides a theoretical analysis of diffraction-limited superresolution, demonstrating that arbitrarily close point sources can be resolved in ideal situations. Precisely, we assume that the incoming signal is a linear combination…

Optimization and Control · Mathematics 2015-08-14 Geoffrey Schiebinger , Elina Robeva , Benjamin Recht

In recent years, there has been a proliferation of wide-field sky surveys to search for a variety of transient objects. Using relatively short focal lengths, the optics of these systems produce undersampled stellar images often marred by a…

Astrophysics · Physics 2009-11-13 Fang Yuan , Carl W. Akerlof

Confocal laser-scanning microscopy (CLSM) is one of the most popular optical architectures for fluorescence imaging. In CLSM, a focused laser beam excites the fluorescence emission from a specific specimen position. Some actuators scan the…

Image and Video Processing · Electrical Eng. & Systems 2023-05-10 Alessandro Zunino , Marco Castello , Giuseppe Vicidomini

This paper proposes a non-computational method of counteracting the effect of image degradation introduced by the diffraction phenomenon in lensless microscopy. All the optical images (whether focused by lenses or not) are diffraction…

Optics · Physics 2021-04-08 Sanjeev Kumar , Manjunatha Mahadevappa , Pranab Kumar Dutta

In coherent diffractive imaging (CDI) the resolution of the reconstructed object is limited by the numerical aperture of the experimental setup. We present here a theoretical and numerical study for achieving super-resolution by…

Data Analysis, Statistics and Probability · Physics 2016-09-20 Tatiana Latychevskaia , Yuriy Chushkin , Hans-Werner Fink

High angular resolution X-ray imaging is always demanded by astrophysics and solar physics, which can be realized by coded-mask imaging with very long mask-detector distance in principle. Previously the diffraction-interference effect has…

Astrophysics · Physics 2009-11-13 Chen Zhang , Shuang Nan Zhang

Two features desired in a three-dimensional (3D) optical tomographic image reconstruction algorithm are the ability to reduce imaging artifacts and to do fast processing of large data volumes. Traditional iterative inversion algorithms are…

Image and Video Processing · Electrical Eng. & Systems 2020-06-15 Zihui Wu , Yu Sun , Alex Matlock , Jiaming Liu , Lei Tian , Ulugbek S. Kamilov

Diffusion models have recently gained traction as a powerful class of deep generative priors, excelling in a wide range of image restoration tasks due to their exceptional ability to model data distributions. To solve image restoration…

Image and Video Processing · Electrical Eng. & Systems 2025-06-10 Xiang Li , Soo Min Kwon , Shijun Liang , Ismail R. Alkhouri , Saiprasad Ravishankar , Qing Qu

Light-field microscopy represents a promising solution for microscopic volumetric imaging, thanks to its capability to encode information on multiple planes in a single acquisition. This is achieved through its peculiar simultaneous capture…

This study investigates the application of Super-Resolution techniques in holographic microscopy to enhance quantitative phase imaging. An off-axis Mach-Zehnder interferometric setup was employed to capture interferograms. The study…

Undersampled images, such as those produced by the HST WFPC-2, misrepresent fine-scale structure intrinsic to the astronomical sources being imaged. Analyzing such images is difficult on scales close to their resolution limits and may…

Astrophysics · Physics 2009-10-31 Tod R. Lauer

Machine learning is attracting surging interest across nearly all scientific areas by enabling the analysis of large datasets and the extraction of scientific information from incomplete data. Data-driven science is rapidly growing,…

Applied Physics · Physics 2025-03-17 Sung Yun Lee , Do Hyung Cho , Chulho Jung , Daeho Sung , Daewoong Nam , Sangsoo Kim , Changyong Song

This work addresses image restoration tasks through the lens of inverse problems using unpaired datasets. In contrast to traditional approaches -- which typically assume full knowledge of the forward model or access to paired degraded and…

Computer Vision and Pattern Recognition · Computer Science 2025-06-18 Giacomo Meanti , Thomas Ryckeboer , Michael Arbel , Julien Mairal

Acoustic-Resolution Photoacoustic Microscopy (AR-PAM) is promising for subcutaneous vascular imaging, but its spatial resolution is constrained by the Point Spread Function (PSF). Traditional deconvolution methods like Richardson-Lucy and…

Computer Vision and Pattern Recognition · Computer Science 2024-10-29 Youshen Xiao , Sheng Liao , Xuanyang Tian , Fan Zhang , Xinlong Dong , Yunhui Jiang , Xiyu Chen , Ruixi Sun , Yuyao Zhang , Fei Gao

Lensless imaging is an elegant approach to high-resolution microscopy, which is rapidly gaining popularity in applications where imaging optics are problematic. However, current lensless imaging methods require objects to be placed within a…

We present an analytical description and an experimental realization of interscale mixing microscopy, a diffraction-based imaging technique that is capable of detecting wavelength/10 objects in far-field measurements with both coherent and…

Synthetic aperture sonar (SAS) requires precise positional and environmental information to produce well-focused output during the image reconstruction step. However, errors in these measurements are commonly present resulting in defocused…

Image and Video Processing · Electrical Eng. & Systems 2021-08-02 Isaac Gerg , Vishal Monga
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