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Two-photon (2P) microscopy is a powerful technique for deep-tissue fluorescence imaging; however, tissue scattering limits its effectiveness for depth imaging using conventional approaches. Despite typical strategies having been put forward…

Optics · Physics 2025-05-21 Lei Zhu , Bernhard Rauer , Hilton B. De Aguiar , Sylvain Gigan

The purpose of this paper is to study the interaction between a two-level system and two continuous-mode photons. Two scenarios are investigated: Case 1, how a two-level system changes the pulse shapes of two input photons propagating in a…

Quantum Physics · Physics 2019-10-14 Zhiyuan Dong , Guofeng Zhang , Nina H. Amini

Recent advances in spatial omics technologies have revolutionized our ability to study biological systems with unprecedented resolution. By preserving the spatial context of molecular measurements, these methods enable comprehensive mapping…

Quantitative Methods · Quantitative Biology 2025-09-18 Zhiwei Fan , Tiangang Wang , Kexin Huang , Binwu Ying , Xiaobo Zhou

In wide-field nonlinear microscopy, wavefront modulation by means of phase-only spatial light modulators (SLMs) allows achieving simultaneous two-photon excitation and fluorescence emission from specific region-of-interests (ROIs) of…

Inspection of tissues using a light microscope is the primary method of diagnosing many diseases, notably cancer. Highly multiplexed tissue imaging builds on this foundation, enabling the collection of up to 60 channels of molecular…

This paper proposes an interactive system for mobile devices controlled by hand gestures aimed at helping people with visual impairments. This system allows the user to interact with the device by making simple static and dynamic hand…

Computer Vision and Pattern Recognition · Computer Science 2022-07-27 Samer Alashhab , Antonio Javier Gallego , Miguel Ángel Lozano

In the present work, electroencephalographic recordings of healthy human participants were performed to study the entrainment of brainwaves using a variety of stimulus. First, periodic entrainment of the brainwaves was studied using two…

Neurons and Cognition · Quantitative Biology 2019-01-04 Richa Phogat , P. Parmananda

As computing resource demands continue to escalate in the face of big data, cloud-connectivity and the internet of things, it has become imperative to develop new low-power, scalable architectures. Neuromorphic photonics, or photonic neural…

Transcranial photobiomodulation is an optical method for non-invasive brain stimulation. The method projects red and near-infrared light through the scalp within 600-1100 nm and low energy within the 1-20 J/cm2 range. Recent studies have…

Numerical Analysis · Mathematics 2022-12-12 Faezeh Ibrahimi , Mehdi Delrobaei

We study composite spatial optical solitons supported by two-wave mutual focusing induced by cross-phase modulation in Kerr-like nonlinear media. We find the families of both single- and two-hump solitons and discuss their properties and…

Pattern Formation and Solitons · Physics 2009-04-01 Jose R. Salgueiro , Andrey A. Sukhorukov , Yuri S. Kivshar

Realizing a strong interaction between individual optical photons is an important objective of research in quantum science and technology. Since photons do not interact directly, this goal requires, e.g., an optical medium in which the…

Quantum Physics · Physics 2015-06-19 Jürgen Volz , Michael Scheucher , Christian Junge , Arno Rauschenbeutel

Multi-photon propagation in connected structures - a quantum walk - offers the potential for simulating complex physical systems and provides a route to universal quantum computation. Increasing the complexity of quantum photonic networks…

Quantum Physics · Physics 2016-03-21 Hugo Defienne , Marco Barbieri , Ian A. Walmsley , Brian J. Smith , Sylvain Gigan

Photonic integrated circuits with second-order ($\chi^{(2)}$) nonlinearities are rapidly scaling to remarkably low powers. At this time, state-of-the-art devices achieve saturated nonlinear interactions with thousands of photons when driven…

Photonic technologies offer great prospects for novel ultrafast, energy-efficient and hardware-friendly neuromorphic (brain-like) computing platforms. Moreover, neuromorphic photonic approaches based upon ubiquitous, technology-mature and…

Emerging Technologies · Computer Science 2022-11-23 Dafydd Owen-Newns , Joshua Robertson , Matej Hejda , Antonio Hurtado

We report how the unique temporal and spectral features of pulsed entangled photons from a parametric downconversion source can be utilized for manipulating electronic excitations through the optimization of their spectral phase. A new…

Chemical Physics · Physics 2024-09-18 Sajal Kumar Giri , George C. Schatz

Photonic brain-inspired platforms are emerging as novel analog computing devices, enabling fast and energy-efficient operations for machine learning. These artificial neural networks generally require tailored optical elements, such as…

Emerging Technologies · Computer Science 2021-07-30 Davide Pierangeli , Giulia Marcucci , Claudio Conti

The present paper examines the viability of a radically novel idea for brain-computer interface (BCI), which could lead to novel technological, experimental and clinical applications. BCIs are computer-based systems that enable either…

Neurons and Cognition · Quantitative Biology 2021-12-03 Vahid Salari , Serafim Rodrigues , Erhan Saglamyurek , Christoph Simon , Daniel Oblak

Brain-computer interfaces are being explored for a wide variety of therapeutic applications. Typically, this involves measuring and analyzing continuous-time electrical brain activity via techniques such as electrocorticogram (ECoG) or…

Neural and Evolutionary Computing · Computer Science 2023-04-28 Yiming Ai , Bipin Rajendran

We present an optimized conductance-based retina microcircuit simulator which transforms light stimuli into a series of graded and spiking action potentials through photo transduction. We use discrete retinal neuron blocks based on a…

Neurons and Cognition · Quantitative Biology 2020-01-16 Jason K. Eshraghian , Seungbum Baek , Wesley Thio , Yulia Sandamirskaya , Herbert H. C. Iu , Wei D. Lu

There has been a recent surge of interest in the implementation of linear operations such as matrix multipications using photonic integrated circuit technology. However, these approaches require an efficient and flexible way to perform…