Related papers: From slides to AI-ready maps: Standardized multi-l…
In computation pathology, the pyramid structure of gigapixel Whole Slide Images (WSIs) has recently been studied for capturing various information from individual cell interactions to tissue microenvironments. This hierarchical structure is…
The last decade has seen significant advances in computer-aided diagnostics for cytological screening, mainly through the improvement and integration of scanning techniques such as whole slide imaging (WSI) and the combination with deep…
Mycosis fungoides (MF) is a rare, potentially life threatening skin disease, which in early stages clinically and histologically strongly resembles Eczema, a very common and benign skin condition. In order to increase the survival rate, one…
Enhancing the robustness of deep learning models against adversarial attacks is crucial, especially in critical domains like healthcare where significant financial interests heighten the risk of such attacks. Whole slide images (WSIs) are…
Advancements in digital pathology and computing resources have made a significant impact in the field of computational pathology for breast cancer diagnosis and treatment. However, access to high-quality labeled histopathological images of…
Pathology is essential for cancer diagnosis, with multiple instance learning (MIL) widely used for whole slide image (WSI) analysis. WSIs exhibit a natural hierarchy -- patches, regions, and slides -- with distinct semantic associations.…
In computational pathology, multiple instance learning (MIL) is widely used to circumvent the computational impasse in giga-pixel whole slide image (WSI) analysis. It usually consists of two stages: patch-level feature extraction and…
Using features extracted from networks pretrained on ImageNet is a common practice in applications of deep learning for digital pathology. However it presents the downside of missing domain specific image information. In digital pathology,…
Lifelong learning for whole slide images (WSIs) poses the challenge of training a unified model to perform multiple WSI-related tasks, such as cancer subtyping and tumor classification, in a distributed, continual fashion. This is a…
Whole-slide image (WSI) preprocessing, comprising tissue detection followed by patch extraction, is foundational to AI-driven computational pathology but remains a major bottleneck for scaling to large and heterogeneous cohorts. We present…
Analyzing high resolution whole slide images (WSIs) with regard to information across multiple scales poses a significant challenge in digital pathology. Multi-instance learning (MIL) is a common solution for working with high resolution…
Accurate survival prediction from histopathology whole-slide images (WSIs) remains challenging due to their gigapixel resolution, strong spatial heterogeneity, and complex survival distributions. We introduce a comprehensive computational…
Consecutive thin sections of tissue samples make it possible to study local variation in e.g. protein expression and tumor heterogeneity by staining for a new protein in each section. In order to compare and correlate patterns of different…
Whole-slide images (WSIs) from cancer patients contain rich information that can be used for medical diagnosis or to follow treatment progress. To automate their analysis, numerous deep learning methods based on convolutional neural…
Motivation: High resolution 2D whole slide imaging provides rich information about the tissue structure. This information can be a lot richer if these 2D images can be stacked into a 3D tissue volume. A 3D analysis, however, requires…
Whole Slide Imaging (WSI) has become a gold standard in cancer diagnosis, inspecting multi-scale information from cellular to tissue levels. Processing an entire WSI directly is infeasible due to GPU memory constraints; thus, Multiple…
Automatic integration of whole slide images (WSIs) and gene expression profiles has demonstrated substantial potential in precision clinical diagnosis and cancer progression studies. However, most existing studies focus on individual gene…
Whole-slide images (WSI) glomerulus segmentation is essential for accurately diagnosing kidney diseases. In this work, we propose a general and practical pipeline for glomerulus segmentation that effectively enhances both patch-level and…
Whole Slide Images (WSIs) or histopathology images are used in digital pathology. WSIs pose great challenges to deep learning models for clinical diagnosis, owing to their size and lack of pixel-level annotations. With the recent…
Considering the profound transformation affecting pathology practice, we aimed to develop a scalable artificial intelligence (AI) system to diagnose colorectal cancer from whole-slide images (WSI). For this, we propose a deep learning (DL)…