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Recognition of mitotic figures in histologic tumor specimens is highly relevant to patient outcome assessment. This task is challenging for algorithms and human experts alike, with deterioration of algorithmic performance under shifts in…
Neuro-oncology poses unique challenges for machine learning due to heterogeneous data and tumor complexity, limiting the ability of foundation models (FMs) to generalize across cohorts. Existing FMs also perform poorly in predicting…
Due to the over-fitting problem caused by imbalance samples, there is still room to improve the performance of data-driven automatic modulation classification (AMC) in noisy scenarios. By fully considering the signal characteristics, an AMC…
Accurate evaluation of the response of glioblastoma to therapy is crucial for clinical decision-making and patient management. The Response Assessment in Neuro-Oncology (RANO) criteria provide a standardized framework to assess patients'…
Mitotic figures represent a key histoprognostic feature in tumor pathology, providing crucial insights into tumor aggressiveness and proliferation. However, their identification remains challenging, subject to significant inter-observer…
Breast density assessment is a crucial component of mammographic interpretation, with high breast density (BI-RADS categories C and D) representing both a significant risk factor for developing breast cancer and a technical challenge for…
Accurate classification of brain tumors from magnetic resonance imaging (MRI) plays a critical role in early diagnosis and effective treatment planning. In this study, we propose a deep learning framework based on Vision Transformers (ViT)…
Counting of mitotic figures is a fundamental step in grading and prognostication of several cancers. However, manual mitosis counting is tedious and time-consuming. In addition, variation in the appearance of mitotic figures causes a high…
This paper proposes to use deep radiomic features (DRFs) from a convolutional neural network (CNN) to model fine-grained texture signatures in the radiomic analysis of recurrent glioblastoma (rGBM). We use DRFs to predict survival of rGBM…
The count of mitotic figures (MFs) observed in hematoxylin and eosin (H&E)-stained slides is an important prognostic marker as it is a measure for tumor cell proliferation. However, the identification of MFs has a known low inter-rater…
Automating brain tumor segmentation using deep learning methods is an ongoing challenge in medical imaging. Multiple lingering issues exist including domain-shift and applications in low-resource settings which brings a unique set of…
Content-based mammographic image retrieval systems require exact BIRADS categorical matching across five distinct classes, presenting significantly greater complexity than binary classification tasks commonly addressed in literature.…
Accurate breast MRI lesion detection is critical for early cancer diagnosis, especially in high-risk populations. We present a classification pipeline that adapts a pretrained foundation model, the Medical Slice Transformer (MST), for…
Annotation cost is a bottleneck for collecting massive data in mammography, especially for training deep neural networks. In this paper, we study the use of heterogeneous levels of annotation granularity to improve predictive performances.…
Finite Mixture Regression (FMR) refers to the mixture modeling scheme which learns multiple regression models from the training data set. Each of them is in charge of a subset. FMR is an effective scheme for handling sample heterogeneity,…
Hematological disorders, which involve a variety of malignant conditions and genetic diseases affecting blood formation, present significant diagnostic challenges. One such major challenge in clinical settings is differentiating…
Association Rule Mining (ARM) is a fundamental task for knowledge discovery in tabular data and is widely used in high-stakes decision-making. Classical ARM methods rely on frequent itemset mining, leading to rule explosion and poor…
Simulating physical systems is essential in engineering, but analytical solutions are limited to straightforward problems. Consequently, numerical methods like the Finite Element Method (FEM) are widely used. However, the FEM becomes…
Cancer detection and classification from gigapixel whole slide images of stained tissue specimens has recently experienced enormous progress in computational histopathology. The limitation of available pixel-wise annotated scans shifted the…
In medical imaging, most of the image registration methods implicitly assume a one-to-one correspondence between the source and target images (i.e., diffeomorphism). However, this is not necessarily the case when dealing with pathological…