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Background: Enlargement of perivascular spaces (PVS) is common in neurodegenerative disorders including cerebral small vessel disease, Alzheimer's disease, and Parkinson's disease. PVS enlargement may indicate impaired clearance pathways…

Image and Video Processing · Electrical Eng. & Systems 2025-02-17 William Pham , Alexander Jarema , Donggyu Rim , Zhibin Chen , Mohamed S. H. Khlif , Vaughan G. Macefield , Luke A. Henderson , Amy Brodtmann

BACKGROUND AND PURPOSE: Deep learning has been demonstrated effective in many neuroimaging applications. However, in many scenarios, the number of imaging sequences capturing information related to small vessel disease lesions is…

Perivascular spaces(PVSs) form a central component of the brain\'s waste clearance system, the glymphatic system. These structures are visible on MRI images, and their morphology is associated with aging and neurological disease. Manual…

Blood vessels of the brain provide the human brain with the required nutrients and oxygen. As a vulnerable part of the cerebral blood supply, pathology of small vessels can cause serious problems such as Cerebral Small Vessel Diseases…

The analysis of retinal images for the diagnosis of various diseases is one of the emerging areas of research. Recently, the research direction has been inclined towards investigating several changes in retinal blood vessels in subjects…

Image and Video Processing · Electrical Eng. & Systems 2024-12-10 Mehwish Mehmood , Shahzaib Iqbal , Tariq Mahmood Khan , Ivor Spence , Muhammad Fahim

To analyze this characteristic of vulnerability, we developed an automated deep learning method for detecting microvessels in intravascular optical coherence tomography (IVOCT) images. A total of 8,403 IVOCT image frames from 85 lesions and…

Many studies regarding the vasculature of biological tissues involve the segmentation of the blood vessels in a sample followed by the creation of a graph structure to model the vasculature. The graph is then used to extract relevant…

Computer Vision and Pattern Recognition · Computer Science 2024-06-21 João Pedro Parella , Matheus Viana da Silva , Cesar Henrique Comin

Automated blood vessel segmentation is vital for biomedical imaging, as vessel changes indicate many pathologies. Still, precise segmentation is difficult due to the complexity of vascular structures, anatomical variations across patients,…

The health and function of tissue rely on its vasculature network to provide reliable blood perfusion. Volumetric imaging approaches, such as multiphoton microscopy, are able to generate detailed 3D images of blood vessels that could…

Computer Vision and Pattern Recognition · Computer Science 2019-06-19 Mohammad Haft-Javaherian , Linjing Fang , Victorine Muse , Chris B. Schaffer , Nozomi Nishimura , Mert R. Sabuncu

Analyzing the morphological attributes of blood vessels plays a critical role in the computer-aided diagnosis of many cardiovascular and ophthalmologic diseases. Although being extensively studied, segmentation of blood vessels,…

Image and Video Processing · Electrical Eng. & Systems 2020-10-12 Yicheng Wu , Chengwei Pan , Shuqi Wang , Ming Zhang , Yong Xia , Yizhou Yu

Precise 3D segmentation of cerebral vasculature from T1-weighted contrast-enhanced (T1CE) MRI is crucial for safe neurosurgical planning. Manual delineation is time-consuming and prone to inter-observer variability, while current automated…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Mohammad Jafari Vayeghan , Niloufar Delfan , Mehdi Tale Masouleh , Mansour Parvaresh Rizi , Behzad Moshiri

Automated volumetric segmentation of the pancreas on cross-sectional imaging is needed for diagnosis and follow-up of pancreatic diseases. While CT-based pancreatic segmentation is more established, MRI-based segmentation methods are…

Neuroanatomical segmentation in magnetic resonance imaging (MRI) of the brain is a prerequisite for volume, thickness and shape measurements. This work introduces a new highly accurate and versatile method based on 3D convolutional neural…

Quantitative Methods · Quantitative Biology 2019-02-07 Philip Novosad , Vladimir Fonov , D. Louis Collins

Background: The hippocampus plays a crucial role in memory and cognition. Because of the associated toxicity from whole brain radiotherapy, more advanced treatment planning techniques prioritize hippocampal avoidance, which depends on an…

Medical Physics · Physics 2023-06-16 Yang Lei , Yifu Ding , Richard L. J. Qiu , Tonghe Wang , Justin Roper , Yabo Fu , Hui-Kuo Shu , Hui Mao , Xiaofeng Yang

Previous studies on echocardiogram segmentation are focused on the left ventricle in parasternal long-axis views. In this study, deep-learning models were evaluated on the segmentation of the ventricles in parasternal short-axis…

Image and Video Processing · Electrical Eng. & Systems 2025-04-04 Julian Rene Cuellar Buritica , Vu Dinh , Manjula Burri , Julie Roelandts , James Wendling , Jon D. Klingensmith

Ventricular volume and its progression are known to be linked to several brain diseases such as dementia and schizophrenia. Therefore accurate measurement of ventricle volume is vital for longitudinal studies on these disorders, making…

Computer Vision and Pattern Recognition · Computer Science 2018-03-06 Mohsen Ghafoorian , Jonas Teuwen , Rashindra Manniesing , Frank-Erik de Leeuw , Bram van Ginneken , Nico Karssemeijer , Bram Platel

Automatic and consistent meningioma segmentation in T1-weighted MRI volumes and corresponding volumetric assessment is of use for diagnosis, treatment planning, and tumor growth evaluation. In this paper, we optimized the segmentation and…

Image and Video Processing · Electrical Eng. & Systems 2021-09-24 David Bouget , André Pedersen , Sayied Abdol Mohieb Hosainey , Johanna Vanel , Ole Solheim , Ingerid Reinertsen

Automatic identification of brain lesions from magnetic resonance imaging (MRI) scans of stroke survivors would be a useful aid in patient diagnosis and treatment planning. We propose a multi-modal multi-path convolutional neural network…

Computer Vision and Pattern Recognition · Computer Science 2019-05-28 Yunzhe Xue , Fadi G. Farhat , Olga Boukrina , A . M. Barrett , Jeffrey R. Binder , Usman W. Roshan , William W. Graves

Identification of vessel structures of different sizes in biomedical images is crucial in the diagnosis of many neurodegenerative diseases. However, the sparsity of good-quality annotations of such images makes the task of vessel…

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