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Structural studies of biological macromolecules are severely limited by radiation damage. Traditional crystallography curbs the effects of damage by spreading damage over many copies of the molecule of interest. X-ray lasers, such as the…

Two-dimensional images carried by optical pulses (2 ns) are delayed by up to 10 ns in a 10 cm cesium vapor cell. By interfering the delayed images with a local oscillator, the transverse phase and amplitude profiles of the images are shown…

Visual anomaly inspection is critical in manufacturing, yet hampered by the scarcity of real anomaly samples for training robust detectors. Synthetic data generation presents a viable strategy for data augmentation; however, current methods…

Computer Vision and Pattern Recognition · Computer Science 2025-09-17 Linchun Wu , Qin Zou , Xianbiao Qi , Bo Du , Zhongyuan Wang , Qingquan Li

Measuring subdiffraction separations between single fluorescent particles is important for biological, nano-, and medical-technology studies. Major challenges include (i) measuring changing molecular separations with high temporal…

Biological Physics · Physics 2015-05-18 Shawn H. DeCenzo , Michael C. DeSantis , Y. M. Wang

We present a novel method for Ankylography: three-dimensional structure reconstruction from a single shot diffraction intensity pattern. Our approach allows reconstruction of objects containing many more details than was ever demonstrated,…

Optics · Physics 2012-03-22 Eliyahu Osherovich , Oren Cohen , Yonina C. Eldar , Mordechai Segev

Specular reflection exists widely in photography and causes the recorded color deviating from its true value, so fast and high quality highlight removal from a single nature image is of great importance. In spite of the progress in the past…

Computer Vision and Pattern Recognition · Computer Science 2015-12-02 Dongsheng An , Jinli Suo , Xiangyang Ji , Haoqian Wang , Qionghai Dai

A unified method for three-dimensional reconstruction of objects from transmission images collected at multiple illumination directions is described. The method may be applicable to experimental conditions relevant to absorption-based,…

Medical Physics · Physics 2022-12-07 Timur E. Gureyev , Hamish G. Brown , Harry M. Quiney , Leslie J. Allen

Deconvolution phase microscopy enables high-contrast visualization of transparent samples through reconstructions of their transmitted phases or refractive indexes. Herein, we propose a method to extend 2D deconvolution phase microscopy to…

Optics · Physics 2022-04-20 Herve Hugonnet , Mahn Jae Lee , Yongkeun Park

We demonstrate the application of event-driven Timepix3-based detectors in combination with a double-sided velocity-map-imaging spectrometer to record the full 3D momentum of charged particles at the free-electron-laser facility FLASH. We…

Optical tweezers, the three-dimensional confinement of a nanoparticle by a strongly focused beam of light, have been widely employed in investigating biomaterial nanomechanics, nanoscopic fluid properties, and ultrasensitive detections in…

X-ray ptychography has revolutionised nanoscale phase contrast imaging at large-scale synchrotron sources in recent years. We present here the first successful demonstration of the technique in a small-scale laboratory setting. We conducted…

Diffusion models have demonstrated remarkable efficacy in generating high-quality samples. Existing diffusion-based image restoration algorithms exploit pre-trained diffusion models to leverage data priors, yet they still preserve elements…

Image and Video Processing · Electrical Eng. & Systems 2024-08-07 Hongjie Wu , Linchao He , Mingqin Zhang , Dongdong Chen , Kunming Luo , Mengting Luo , Ji-Zhe Zhou , Hu Chen , Jiancheng Lv

Many camera sensors use a dual-pixel (DP) design that operates as a rudimentary light field providing two sub-aperture views of a scene in a single capture. The DP sensor was developed to improve how cameras perform autofocus. Since the DP…

Computer Vision and Pattern Recognition · Computer Science 2022-02-11 Abdullah Abuolaim , Mahmoud Afifi , Michael S. Brown

Ultrafast electron beam X-ray computed tomography produces noisy data due to short measurement times, causing reconstruction artifacts and limiting overall image quality. To counteract these issues, two self-supervised deep learning methods…

Machine Learning · Computer Science 2025-11-24 Israt Jahan Tulin , Sebastian Starke , Dominic Windisch , André Bieberle , Peter Steinbach

Nanostrucured Europium oxide and hydroxide films were obtained by pulsed Nd:Yag (532 nm) laser ablation of an Europium metallic target, in the presence of a 1 mbar Helium buffer atmosphere. Both the produced film and the ambient plasma were…

Coherent diffraction imaging (CDI) using synchrotron radiation, X-ray free electron lasers (X-FELs), high harmonic generation, soft X-ray lasers, and optical lasers has found broad applications across several disciplines. An active research…

Moving towards significantly smaller nanostructures, direct structuring techniques such as electron beam lithography approach fundamental limitations in feature size and aspect ratios. Application of nanostructures like diffractive X-ray…

We introduce a time-delayed beam splitting method based on the energy separation of x-ray photon beams. It is implemented and theoretically substantiated on an example of an x-ray optical scheme similar to that of the classical Michelson…

Optics · Physics 2013-11-26 Yuri P. Stetsko , Yuri V. Shvyd'ko , G. Brian Stephenson

The low repetition rates and possible shot-to-shot variations in laser-plasma studies place a high value on single-shot diagnostics. For example, white-beam scattering methods based on broadband backlighter x-ray sources are used to…

Plasma Physics · Physics 2014-03-04 O. R. Hoidn , G. T. Seidler