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Simulations of quantum chemistry and quantum materials are believed to be among the most important potential applications of quantum information processors, but realizing practical quantum advantage for such problems is challenging. Here,…

ML4Chem is an open-source machine learning library for chemistry and materials science. It provides an extendable platform to develop and deploy machine learning models and pipelines and is targeted to the non-expert and expert users.…

Chemical Physics · Physics 2020-03-31 Muammar El Khatib , Wibe A de Jong

A novel parallel hybrid quantum-classical algorithm for the solution of the quantum-chemical ground-state energy problem on gate-based quantum computers is presented. This approach is based on the reduced density-matrix functional theory…

Reliable predictions of the behaviour of chemical systems are essential across many industries, from nanoscale engineering over validation of advanced materials to nanotoxicity assessment in health and medicine. For the future we therefore…

Chemical Physics · Physics 2021-03-05 Judith B. Rommel

The PySCF package has emerged as a powerful and flexible open-source platform for quantum chemistry simulations. However, the efficiency of electronic structure calculations can vary significantly depending on the choice of computational…

Chemical Physics · Physics 2025-06-10 Zhichen Pu , Qiming Sun

To enhance large language models (LLMs) for chemistry problem solving, several LLM-based agents augmented with tools have been proposed, such as ChemCrow and Coscientist. However, their evaluations are narrow in scope, leaving a large gap…

Artificial Intelligence · Computer Science 2025-05-27 Botao Yu , Frazier N. Baker , Ziru Chen , Garrett Herb , Boyu Gou , Daniel Adu-Ampratwum , Xia Ning , Huan Sun

Quantum cloud computing is an emerging computing paradigm that allows seamless access to quantum hardware as cloud-based services. However, effective use of quantum resources is challenging and necessitates robust simulation frameworks for…

Emerging Technologies · Computer Science 2024-05-03 Hoa T. Nguyen , Muhammad Usman , Rajkumar Buyya

Multimodal large language models (MLLMs) have made impressive progress in many applications in recent years. However, chemical MLLMs that can handle cross-modal understanding and generation remain underexplored. To fill this gap, we propose…

Machine Learning · Computer Science 2025-08-05 Qian Tan , Dongzhan Zhou , Peng Xia , Wanhao Liu , Wanli Ouyang , Lei Bai , Yuqiang Li , Tianfan Fu

Progress towards quantum utility in chemistry requires not only algorithmic advances, but also the identification of chemically meaningful problems whose electronic structure fundamentally challenges classical methods. Here, we introduce a…

Chemical Physics · Physics 2026-01-19 Srivathsan Poyyapakkam Sundar , Vibin Abraham , Bo Peng , Ayush Asthana

Quantum parameter estimation promises a high-precision measurement in theory, however, how to design the optimal scheme in a specific scenario, especially under a practical condition, is still a serious problem that needs to be solved case…

Astrochemical simulations are a powerful tool for revealing chemical evolution in the interstellar medium. Astrochemical calculations require efficient processing of large matrices for the chemical networks. The large chemical reaction…

Instrumentation and Methods for Astrophysics · Physics 2023-12-11 Kazutaka Motoyama , Ruben Krasnopolsky , Hsien Shang , Kento Aida , Eisaku Sakane

Chemical reaction engineering is key to industrial might and sustainable chemistry. This will be enabled using smart, efficient catalysts or catalysis ecosystems. This is possible with advanced artificial intelligence and machine learning…

Chemical Physics · Physics 2026-03-09 Rigoberto Advincula , Jihua Chen

The development of materials science is undergoing a shift from empirical approaches to data-driven and algorithm-oriented research paradigm. The state-of-the-art platforms are confined to inorganic crystals, with limited chemical space,…

Materials Science · Physics 2025-07-08 Jifeng Wang , Jiazhe Ju , Ying Wang

The development of synthesis procedures remains a fundamental challenge in materials discovery, with procedural knowledge scattered across decades of scientific literature in unstructured formats that are challenging for systematic…

Compendium Manager is a command-line tool written in Python to automate the provisioning, launch, and evaluation of bioinformatics pipelines. Although workflow management tools such as Snakemake and Nextflow enable users to automate the…

Genomics · Quantitative Biology 2025-05-19 Richard J. Abdill , Ran Blekhman

Running complex sets of machine learning experiments is challenging and time-consuming due to the lack of a unified framework. This leaves researchers forced to spend time implementing necessary features such as parallelization, caching,…

Machine Learning · Computer Science 2023-11-22 Zac Pullar-Strecker , Xinglong Chang , Liam Brydon , Ioannis Ziogas , Katharina Dost , Jörg Wicker

The Combustion Toolbox (CT) is a newly developed open-source thermochemical code designed to solve problems involving chemical equilibrium for both gas- and condensed-phase species. The kernel of the code is based on the theoretical…

Chemical Physics · Physics 2026-01-06 Alberto Cuadra , César Huete , Marcos Vera

Artificial intelligence is transforming molecular and materials science, but its growing computational and data demands raise critical sustainability challenges. In this Perspective, we examine resource considerations across the AI-driven…

Chemistry experiments can be resource- and labor-intensive, often requiring manual tasks like polishing electrodes in electrochemistry. Traditional lab automation infrastructure faces challenges adapting to new experiments. To address this,…

Purpose: As interest in CEST-MRI grows, particularly in the preclinical setting, the necessity for standardized and easy-to-use acquisition and data analysis pipelines has become apparent. While vendors have increasingly introduced support…

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