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Understanding how cellular morphology, gene expression, and spatial context jointly shape tissue function is a central challenge in biology. Image-based spatial transcriptomics technologies now provide high-resolution measurements of cell…

Quantitative Methods · Quantitative Biology 2026-02-17 Zhenglun Kong , Mufan Qiu , John Boesen , Xiang Lin , Sukwon Yun , Tianlong Chen , Manolis Kellis , Marinka Zitnik

Restoring face images from distortions is important in face recognition applications and is challenged by multiple scale issues, which is still not well-solved in research area. In this paper, we present a Sequential Gating Ensemble Network…

Computer Vision and Pattern Recognition · Computer Science 2018-05-08 Jianxin Lin , Tiankuang Zhou , Zhibo Chen

The joint interpretation of multi-modal and multi-view fundus images is critical for retinopathy prevention, as different views can show the complete 3D eyeball field and different modalities can provide complementary lesion areas. Compared…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 Yonghao Huang , Leiting Chen , Chuan Zhou

Addressing the challenge of multimodal data fusion in high-dimensional biomedical informatics, we propose MMCTOP, a MultiModal Clinical-Trial Outcome Prediction framework that integrates heterogeneous biomedical signals spanning (i)…

Machine Learning · Computer Science 2025-12-29 Carolina Aparício , Qi Shi , Bo Wen , Tesfaye Yadete , Qiwei Han

Multimodal medical images play a crucial role in the precise and comprehensive clinical diagnosis. Diffusion model is a powerful strategy to synthesize the required medical images. However, existing approaches still suffer from the problem…

Computer Vision and Pattern Recognition · Computer Science 2025-05-28 Jiahua Xu , Dawei Zhou , Lei Hu , Zaiyi Liu , Nannan Wang , Xinbo Gao

Medical visual question answering (VQA) aims to answer clinically relevant questions regarding input medical images. This technique has the potential to improve the efficiency of medical professionals while relieving the burden on the…

Computer Vision and Pattern Recognition · Computer Science 2023-02-21 Xinyue Hu , Lin Gu , Kazuma Kobayashi , Qiyuan An , Qingyu Chen , Zhiyong Lu , Chang Su , Tatsuya Harada , Yingying Zhu

Modern operating room is becoming increasingly complex, requiring innovative intra-operative support systems. While the focus of surgical data science has largely been on video analysis, integrating surgical computer vision with language…

Computer Vision and Pattern Recognition · Computer Science 2024-06-25 Kun Yuan , Manasi Kattel , Joel L. Lavanchy , Nassir Navab , Vinkle Srivastav , Nicolas Padoy

Monocular depth estimation is a challenging problem on which deep neural networks have demonstrated great potential. However, depth maps predicted by existing deep models usually lack fine-grained details due to the convolution operations…

Computer Vision and Pattern Recognition · Computer Science 2022-12-06 Yaqiao Dai , Renjiao Yi , Chenyang Zhu , Hongjun He , Kai Xu

Synthesizing multimodality medical data provides complementary knowledge and helps doctors make precise clinical decisions. Although promising, existing multimodal brain graph synthesis frameworks have several limitations. First, they…

Image and Video Processing · Electrical Eng. & Systems 2021-10-11 Islem Mhiri , Mohamed Ali Mahjoub , Islem Rekik

Mental disorders are among the most widespread diseases globally. Analyzing functional brain networks through functional magnetic resonance imaging (fMRI) is crucial for understanding mental disorder behaviors. Although existing fMRI-based…

Neural and Evolutionary Computing · Computer Science 2025-05-26 Jun-En Ding , Dongsheng Luo , Anna Zilverstand , Kaustubh Kulkarni , Feng Liu

Vision-language retrieval-augmented generation (RAG) has become an effective approach for tackling Knowledge-Based Visual Question Answering (KB-VQA), which requires external knowledge beyond the visual content presented in images. The…

Information Retrieval · Computer Science 2025-09-15 Wei Yang , Jingjing Fu , Rui Wang , Jinyu Wang , Lei Song , Jiang Bian

Modern deep neural networks have shown remarkable performance in medical image classification. However, such networks either emphasize pixel-intensity features instead of fundamental anatomical structures (e.g., those encoded by topological…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Pengfei Gu , Huimin Li , Haoteng Tang , Dongkuan , Xu , Erik Enriquez , DongChul Kim , Bin Fu , Danny Z. Chen

Cancer is one of the leading causes of death worldwide, making the development of rapid, minimally invasive, label-free and scalable diagnostic strategies a major challenge in modern oncology. In this context, spectroscopic liquid biopsy…

Accurate classification of pediatric central nervous system tumors remains challenging due to histological complexity and limited training data. While pathology foundation models have advanced whole-slide image (WSI) analysis, they often…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Jian Yu , Joakim Nguyen , Jinrui Fang , Awais Naeem , Zeyuan Cao , Sanjay Krishnan , Nicholas Konz , Tianlong Chen , Chandra Krishnan , Hairong Wang , Edward Castillo , Ying Ding , Ankita Shukla

In real practice, questions are typically complex and knowledge-intensive, requiring Large Language Models (LLMs) to recognize the multifaceted nature of the question and reason across multiple information sources. Iterative and adaptive…

Computation and Language · Computer Science 2025-12-05 Boyi Zhang , Zhuo Liu , Hangfeng He

Recent advances in semantic segmentation of multi-modal remote sensing images have significantly improved the accuracy of tree cover mapping, supporting applications in urban planning, forest monitoring, and ecological assessment.…

Image and Video Processing · Electrical Eng. & Systems 2025-12-16 Yuanyuan Gui , Wei Li , Yinjian Wang , Xiang-Gen Xia , Mauro Marty , Christian Ginzler , Zuyuan Wang

Breast cancer is the most common cancer type in women worldwide. Early detection and appropriate treatment can significantly reduce its impact. While histopathology examinations play a vital role in rapid and accurate diagnosis, they often…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Nematollah Saeidi , Hossein Karshenas , Bijan Shoushtarian , Sepideh Hatamikia , Ramona Woitek , Amirreza Mahbod

Extracting complex structures from grid-based data is a common key step in automated medical image analysis. The conventional solution to recovering tree-structured geometries typically involves computing the minimal cost path through…

Computer Vision and Pattern Recognition · Computer Science 2023-01-03 James Batten , Matthew Sinclair , Ben Glocker , Michiel Schaap

Vision-language foundation models achieve promising performance in natural image classification, yet their direct application to medical imaging is limited by severe domain shifts, resolution mismatches, and the multi-label nature of…

Computer Vision and Pattern Recognition · Computer Science 2026-05-18 Yitong Li , Morteza Ghahremani , Christian Wachinger

Multi-hop question answering (MHQA) enables accurate answers to complex queries by retrieving and reasoning over evidence dispersed across multiple documents. Existing MHQA approaches mainly rely on iterative retrieval-augmented generation,…

Artificial Intelligence · Computer Science 2026-04-21 Wei Chen , Lili Zhao , Zhi Zheng , HuiJun Hou , Tong Xu
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