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While large language models (LLMs) excel at open-ended dialogue, effective psychotherapy requires structured progression and adherence to clinical protocols, making the design of psychotherapist chatbots challenging. We investigate how…

Human-Computer Interaction · Computer Science 2026-04-07 Sina Elahimanesh , Mohammadali Mohammadkhani , Sara Zahedi Movahed , Mohammad Mahdi Abootorabi , Shayan Salehi , Abbas Edalat

Large language model-based multi-agent systems have recently gained significant attention due to their potential for complex, collaborative, and intelligent problem-solving capabilities. Existing surveys typically categorize LLM-based…

Multiagent Systems · Computer Science 2026-05-27 Bingyu Yan , Zhibo Zhou , Litian Zhang , Lian Zhang , Ziyi Zhou , Dezhuang Miao , Zhoujun Li , Chaozhuo Li , Xiaoming Zhang

Safety verification of dynamical systems via barrier certificates is essential for ensuring correctness in autonomous applications. Synthesizing these certificates involves discovering mathematical functions with current methods suffering…

Artificial Intelligence · Computer Science 2026-04-17 Ali Taheri , Alireza Taban , Sadegh Soudjani , Ashutosh Trivedi

The security concerns surrounding Large Language Models (LLMs) have been extensively explored, yet the safety of Multimodal Large Language Models (MLLMs) remains understudied. In this paper, we observe that Multimodal Large Language Models…

Computer Vision and Pattern Recognition · Computer Science 2024-06-21 Xin Liu , Yichen Zhu , Jindong Gu , Yunshi Lan , Chao Yang , Yu Qiao

Large language models (LLMs) and LLM-based agents are increasingly deployed as assistants in planning and decision making, yet most existing systems are implicitly optimized for a single-principal interaction paradigm, in which the model is…

Computation and Language · Computer Science 2026-04-29 Shu Yang , Shenzhe Zhu , Hao Zhu , José Ramón Enríquez , Di Wang , Alex Pentland , Michiel A. Bakker , Jiaxin Pei

Evaluating the quality of open-domain chatbots has become increasingly reliant on LLMs acting as automatic judges. However, existing meta-evaluation benchmarks are static, outdated, and lacking in multilingual coverage, limiting their…

Computation and Language · Computer Science 2026-01-23 John Mendonça , Alon Lavie , Isabel Trancoso

The adoption of large language models (LLMs) in healthcare has attracted significant research interest. However, their performance in healthcare remains under-investigated and potentially limited, due to i) they lack rich domain-specific…

Artificial Intelligence · Computer Science 2024-05-21 Zishan Gu , Fenglin Liu , Changchang Yin , Ping Zhang

In this work, we introduce MedAgentSim, an open-source simulated clinical environment with doctor, patient, and measurement agents designed to evaluate and enhance LLM performance in dynamic diagnostic settings. Unlike prior approaches, our…

Computation and Language · Computer Science 2025-10-02 Mohammad Almansoori , Komal Kumar , Hisham Cholakkal

Integrating language models (LMs) in healthcare systems holds great promise for improving medical workflows and decision-making. However, a critical barrier to their real-world adoption is the lack of reliable evaluation of their…

Computation and Language · Computer Science 2025-12-15 Akash Ghosh , Srivarshinee Sridhar , Raghav Kaushik Ravi , Muhsin Muhsin , Sriparna Saha , Chirag Agarwal

The scarcity of data depicting dangerous situations presents a major obstacle to training AI systems for safety-critical applications, such as construction safety, where ethical and logistical barriers hinder real-world data collection.…

Artificial Intelligence · Computer Science 2025-05-21 Vu Dinh Xuan , Hao Vo , David Murphy , Hoang D. Nguyen

Large language models (LLMs) are gaining increasing interests to improve clinical efficiency for medical diagnosis, owing to their unprecedented performance in modelling natural language. Ensuring the safe and reliable clinical…

Computation and Language · Computer Science 2024-03-26 Lei Liu , Xiaoyan Yang , Fangzhou Li , Chenfei Chi , Yue Shen , Shiwei Lyu Ming Zhang , Xiaowei Ma , Xiangguo Lyu , Liya Ma , Zhiqiang Zhang , Wei Xue , Yiran Huang , Jinjie Gu

Artificial intelligence is increasingly catalyzing scientific automation, with multimodal large language model (MLLM) agents evolving from lab assistants into self-driving lab operators. This transition imposes stringent safety requirements…

Artificial Intelligence · Computer Science 2026-03-13 Qianpu Sun , Xiaowei Chi , Yuhan Rui , Ying Li , Kuangzhi Ge , Jiajun Li , Sirui Han , Shanghang Zhang

Large language models (LLMs) show promise for healthcare question answering, but clinical use is limited by weak verification, insufficient evidence grounding, and unreliable confidence signalling. We propose a multi-agent medical QA…

Computation and Language · Computer Science 2026-02-17 Naeimeh Nourmohammadi , Md Meem Hossain , The Anh Han , Safina Showkat Ara , Zia Ush Shamszaman

The deployment of large language models (LLMs) as interactive agents has exposed a category of behavioral failure that prevailing terminology, principally hallucination, fails to adequately characterize. This paper introduces LLM Psychosis…

Computers and Society · Computer Science 2026-04-30 Ashutosh Raj

When building Large Language Models (LLMs), it is paramount to bear safety in mind and protect them with guardrails. Indeed, LLMs should never generate content promoting or normalizing harmful, illegal, or unethical behavior that may…

Computation and Language · Computer Science 2024-06-25 Simone Tedeschi , Felix Friedrich , Patrick Schramowski , Kristian Kersting , Roberto Navigli , Huu Nguyen , Bo Li

Extending the capabilities of Large Language Models (LLMs) with functions or tools for environment interaction has led to the emergence of the agent paradigm. In industry, training an LLM is not always feasible because of the scarcity of…

Computation and Language · Computer Science 2025-01-14 Saptarshi Sengupta , Harsh Vashistha , Kristal Curtis , Akshay Mallipeddi , Abhinav Mathur , Joseph Ross , Liang Gou

Large Language Models (LLMs) exhibit substantial promise in enhancing task-planning capabilities within embodied agents due to their advanced reasoning and comprehension. However, the systemic safety of these agents remains an underexplored…

Artificial Intelligence · Computer Science 2025-04-22 Yuting Huang , Leilei Ding , Zhipeng Tang , Tianfu Wang , Xinrui Lin , Wuyang Zhang , Mingxiao Ma , Yanyong Zhang

Large language model-powered chatbots have transformed how people seek information, especially in high-stakes contexts like mental health. Despite their support capabilities, safe detection and response to crises such as suicidal ideation…

Computation and Language · Computer Science 2026-04-09 Adrian Arnaiz-Rodriguez , Miguel Baidal , Erik Derner , Jenn Layton Annable , Mark Ball , Mark Ince , Elvira Perez Vallejos , Nuria Oliver

As Large Language Models (LLMs) evolve from static dialogue interfaces to autonomous general agents, effective memory is paramount to ensuring long-term consistency. However, existing benchmarks primarily focus on casual conversation or…

Computation and Language · Computer Science 2026-01-13 Haonan Bian , Zhiyuan Yao , Sen Hu , Zishan Xu , Shaolei Zhang , Yifu Guo , Ziliang Yang , Xueran Han , Huacan Wang , Ronghao Chen

Language Model Models (LLMs) have improved dramatically in the past few years, increasing their adoption and the scope of their capabilities over time. A significant amount of work is dedicated to ``model alignment'', i.e., preventing LLMs…

Computation and Language · Computer Science 2025-04-07 Abhishek Singhania , Christophe Dupuy , Shivam Mangale , Amani Namboori