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Shortest Vector Problem is believed to be hard both for classical and quantum computers. Two of the three NIST post-quantum cryptosystems standardised by NIST rely on its hardness. Research on theoretical and practical performance of…

Quantum Physics · Physics 2025-11-12 Miloš Prokop , Petros Wallden

In this work, we introduce a new iterative quantum algorithm, called Iterative Symphonic Tunneling for Satisfiability problems (IST-SAT), which solves quantum spin glass optimization problems using high-frequency oscillating transverse…

While variational quantum algorithms (VQAs) have demonstrated considerable success in unconstrained optimization, their application to constrained combinatorial problems face a trade-off. Penalty-based methods, despite their circuit…

Quantum Physics · Physics 2026-03-09 Hui-Min Li , Yuan-Liang Han , Zhi-Xi Wang , Shao-Ming Fei

In this study, we analyze various Iterative Stockholder Analysis (ISA) methods for molecular density partitioning, focusing on the numerical performance of the recently proposed Linear approximation of Iterative Stockholder Analysis model…

Chemical Physics · Physics 2025-02-13 YingXing Cheng , Eric Cancès , Virginie Ehrlacher , Alston J. Misquitta , Benjamin Stamm

Variational quantum algorithms are believed to be promising for solving computationally hard problems and are often comprised of repeated layers of quantum gates. An example thereof is the quantum approximate optimization algorithm (QAOA),…

Variational quantum algorithms are viewed as promising candidates for demonstrating quantum advantage on near-term devices. These approaches typically involve the training of parameterized quantum circuits through a classical optimization…

Noisy intermediate-scale quantum cryptanalysis focuses on the capability of near-term quantum devices to solve the mathematical problems underlying cryptography, and serves as a cornerstone for the design of post-quantum cryptographic…

Quantum Physics · Physics 2025-05-14 Xiaokai Hou , Guoqing Zhou , Shan Jin , Yang Li , Wei Huang , Ao Sun , Xiaoting Wang , Bingjie Xu

Assembling genomes from short-read sequencing data remains difficult in repetitive regions, where reference bias and combinatorial complexity limit existing methods. Pangenome-guided sequence assembly (PGSA) mitigates reference bias by…

Quantum Physics · Physics 2026-04-08 Josh Cudby , Sergii Strelchuk

In the noisy intermediate-scale quantum era, emerging classical-quantum hybrid optimization algorithms, such as variational quantum algorithms (VQAs), can leverage the unique characteristics of quantum devices to accelerate computations…

The quantum approximate optimization algorithm (QAOA) is known for its capability and universality in solving combinatorial optimization problems on near-term quantum devices. The results yielded by QAOA depend strongly on its initial…

Quantum Physics · Physics 2022-09-29 Xinwei Lee , Ningyi Xie , Yoshiyuki Saito , Dongsheng Cai , Nobuyoshi Asai

A comparison is made between Exhaustive Search (ES) and Iterative Local Search (ILS). Such comparison was made using the Quantum Approximation Optimization Algorithm (QAOA). QAOA has been extensively researched due to its this potential to…

Quantum Physics · Physics 2022-05-10 Brian García Sarmina

The indefinite least squares (ILS) problem is a generalization of the famous linear least squares problem. It minimizes an indefinite quadratic form with respect to a signature matrix. For this problem, we first propose an impressively…

Numerical Analysis · Mathematics 2022-03-30 Yanjun Zhang , Hanyu Li

Protein folding -- the problem of predicting the spatial structure of a protein given its sequence of amino-acids -- has attracted considerable research effort in biochemistry in recent decades. In this work, we explore the potential of…

Quantum Physics · Physics 2022-04-06 Sami Boulebnane , Xavier Lucas , Agnes Meyder , Stanislaw Adaszewski , Ashley Montanaro

Principal component analysis (PCA) is one of the most powerful tools in machine learning. The simplest method for PCA, the power iteration, requires $\mathcal O(1/\Delta)$ full-data passes to recover the principal component of a matrix with…

Optimization and Control · Mathematics 2017-07-11 Christopher De Sa , Bryan He , Ioannis Mitliagkas , Christopher Ré , Peng Xu

The Quantum Approximate Optimization Algorithm (QAOA) is a standard method for combinatorial optimization with a gate-based quantum computer. The QAOA consists of a particular ansatz for the quantum circuit architecture, together with a…

Quantum Physics · Physics 2020-04-28 Li Li , Minjie Fan , Marc Coram , Patrick Riley , Stefan Leichenauer

In this paper, a new method is proposed for sparse PCA based on the recursive divide-and-conquer methodology. The main idea is to separate the original sparse PCA problem into a series of much simpler sub-problems, each having a closed-form…

Computer Vision and Pattern Recognition · Computer Science 2012-12-03 Qian Zhao , Deyu Meng , Zongben Xu

To compute approximate solutions for combinatorial optimization problems, we describe variational methods based on the product state (PS) and matrix product state (MPS) ansatzes. We perform variational energy minimization with respect to a…

Quantum Physics · Physics 2025-12-24 Guillermo Preisser , Conor Mc Keever , Michael Lubasch

High-resolution images are prevalent in various applications, such as autonomous driving and computer-aided diagnosis. However, training neural networks on such images is computationally challenging and easily leads to out-of-memory errors…

Computer Vision and Pattern Recognition · Computer Science 2023-03-08 Benjamin Bergner , Christoph Lippert , Aravindh Mahendran

The Quantum Approximate Optimization Algorithm (QAOA) has emerged as a promising approach for solving NP hard combinatorial optimization problems on noisy intermediate-scale quantum (NISQ) hardware. However, its performance is critically…

Quantum Physics · Physics 2025-11-13 Rakesh Saini , Nora Mohamed , Saif Al-Kuwari , Ahmed Farouk

Grover's algorithm is a cornerstone of quantum search algorithm, offering quadratic speedup for unstructured problems. However, limited qubit counts and noise in today's noisy intermediate-scale quantum (NISQ) devices hinder large-scale…

Quantum Physics · Physics 2026-01-08 Mei Ian Sam , Tzu-Ling Kuo , Tai-Yue Li