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Sepsis remains a critical challenge due to its high mortality and complex prognosis. To address data limitations in studying MSSA sepsis, we extend existing transfer learning frameworks to accommodate transformation models for…

Applications · Statistics 2025-04-16 Nan Qiao , Haowei Jiang , Cunjie Lin

With sepsis remaining a leading cause of mortality, early identification of patients with sepsis and those at high risk of death is a challenge of high socioeconomic importance. Given the potential of hyperspectral imaging (HSI) to monitor…

Sepsis is a deadly condition affecting many patients in the hospital. Recent studies have shown that patients diagnosed with sepsis have significant mortality and morbidity, resulting from the body's dysfunctional host response to…

Machine Learning · Computer Science 2022-12-14 Ronald Moore , Rishikesan Kamaleswaran

Interest in an electronic health record-based computational model that can accurately predict a patient's risk of sepsis at a given point in time has grown rapidly in the last several years. Like other EHR vendors, the Epic Systems…

Deep learning techniques have emerged as a promising approach to highly accelerated MRI. However, recent reconstruction challenges have shown several drawbacks in current deep learning approaches, including the loss of fine image details…

Computer Vision and Pattern Recognition · Computer Science 2021-09-24 Ruiyang Zhao , Yuxin Zhang , Burhaneddin Yaman , Matthew P. Lungren , Michael S. Hansen

The disease trajectory for clinical sepsis, in terms of temporal cytokine and phenotypic dynamics, can be interpreted as a random dynamical system. The ability to make accurate predictions about patient state from clinical measurements has…

Quantitative Methods · Quantitative Biology 2020-07-30 Dale Larie , Gary An , Chase Cockrell

Machine learning has been widely used in healthcare applications to approximate complex models, for clinical diagnosis, prognosis, and treatment. As deep learning has the outstanding ability to extract information from time series, its true…

Machine Learning · Computer Science 2022-11-14 Ke Liao , Wei Wang , Armagan Elibol , Lingzhong Meng , Xu Zhao , Nak Young Chong

Sepsis is a leading cause of mortality in intensive care units and costs hospitals billions annually. Treating a septic patient is highly challenging, because individual patients respond very differently to medical interventions and there…

Artificial Intelligence · Computer Science 2017-11-28 Aniruddh Raghu , Matthieu Komorowski , Imran Ahmed , Leo Celi , Peter Szolovits , Marzyeh Ghassemi

Although timely sepsis diagnosis and prompt interventions in Intensive Care Unit (ICU) patients are associated with reduced mortality, early clinical recognition is frequently impeded by non-specific signs of infection and failure to detect…

Machine Learning · Computer Science 2018-06-28 Tony Wang , Tom Velez , Emilia Apostolova , Tim Tschampel , Thuy L. Ngo , Joy Hardison

Identifying epileptic seizures through analysis of the electroencephalography (EEG) signal becomes a standard method for the diagnosis of epilepsy. Manual seizure identification on EEG by trained neurologists is time-consuming,…

Machine Learning · Computer Science 2019-06-07 X. Yao , X. Li , Q. Ye , Y. Huang , Q. Cheng , G. -Q. Zhang

Objective: Sepsis is a life-threatening condition caused by severe infection leading to acute organ dysfunction. This study proposes a data-driven metric and a continuous reward function to optimize personalized heparin therapy in surgical…

Machine Learning · Computer Science 2025-12-15 Jiang Liu , Yujie Li , Chan Zhou , Yihao Xie , Qilong Sun , Xin Shu , Peiwei Li , Chunyong Yang , Yiziting Zhu , Jiaqi Zhu , Yuwen Chen , Bo An , Hao Wu , Bin Yi

Sepsis and septic shock are a critical medical condition affecting millions globally, with a substantial mortality rate. This paper uses state-of-the-art deep learning (DL) architectures to introduce a multi-step forecasting system to…

Machine Learning · Computer Science 2023-11-09 Anubhav Bhatti , Yuwei Liu , Chen Dan , Bingjie Shen , San Lee , Yonghwan Kim , Jang Yong Kim

Although recent studies have proposed seizure detection algorithms with good sensitivity performance, there is a remained challenge that they were hard to achieve significantly short detection latency in real-time scenarios. In this…

Signal Processing · Electrical Eng. & Systems 2023-06-29 Yankun Xu , Jie Yang , Wenjie Ming , Shuang Wang , Mohamad Sawan

The unpredictability of seizures continues to distress many people with drug-resistant epilepsy. On account of recent technological advances, considerable efforts have been made using different hardware technologies to realize smart devices…

Emerging Technologies · Computer Science 2022-02-21 Corey Lammie , Wei Xiang , Mostafa Rahimi Azghadi

Epilepsy is a chronic neurological disorder characterized by recurrent unprovoked seizures, affects over 50 million people worldwide, and poses significant risks, including sudden unexpected death in epilepsy (SUDEP). Conventional unimodal…

Neural and Evolutionary Computing · Computer Science 2026-01-12 Ijaz Ahmad , Faizan Ahmad , Sunday Timothy Aboyeji , Yongtao Zhang , Peng Yang , Javed Ali Khan , Rab Nawaz , Baiying Lei

In recent years, the availability of digitized Whole Slide Images (WSIs) has enabled the use of deep learning-based computer vision techniques for automated disease diagnosis. However, WSIs present unique computational and algorithmic…

Image and Video Processing · Electrical Eng. & Systems 2021-06-15 Yash Sharma , Aman Shrivastava , Lubaina Ehsan , Christopher A. Moskaluk , Sana Syed , Donald E. Brown

Sepsis is a life-threatening and serious global health issue. This study combines knowledge with available hospital data to investigate the potential causes of Sepsis that can be affected by policy decisions. We investigate the underlying…

Machine Learning · Computer Science 2025-02-19 Bruno Petrungaro , Neville K. Kitson , Anthony C. Constantinou

Sepsis is a major public health concern due to its high morbidity, mortality, and cost. Its clinical outcome can be substantially improved through early detection and timely intervention. By leveraging publicly available datasets, machine…

Machine Learning · Computer Science 2026-02-04 Yin Jin , Tucker R. Stewart , Deyi Zhou , Chhavi Gupta , Arjita Nema , Scott C. Brakenridge , Grant E. O'Keefe , Juhua Hu

In this study, we developed and tested machine learning models to predict epilepsy surgical outcome using noninvasive clinical and demographic data from patients. Methods: Seven dif-ferent categorization algorithms were used to analyze the…

Epilepsy is one of the most prevalent brain disorders that disrupts the lives of millions worldwide. For patients with drug-resistant seizures, there exist implantable devices capable of monitoring neural activity, promptly triggering…

Signal Processing · Electrical Eng. & Systems 2023-10-31 Arman Zarei , Bingzhao Zhu , Mahsa Shoaran